Granulocyte-macrophage colony
stimulating factor (GM-CSF)

GMCSF
Colony-stimulating factor 2 (CSF2, CSF-2)

Gene: GMCSF maps on chromosome 5q33.1.
mRNA: size: kb.
Protein: a glycosylated homodimer with a molecular weight of 45 kDa.

Cell lines:

Tumors:

Wong G.G. et al. (1985) Human GM-CSF: molecular cloning of the complementary DNA and purification of the natural and recombinant proteins. Science 228, 810-815.
Cantrell M.A. et al. (1985) Cloning, sequence, and expression of a human granulocyte/macrophage colony-stimulating factor. Proc. Nat. Acad. Sci. USA 82, 6250-6254.
Pettenati M.J. et al. (1987) Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders. Proc. Nat. Acad. Sci. USA 84, 2970-2974.