Practice Quiz For Test 2

 

-In children Blood cells are formed predominantly in which of the following? D

A.  Sternum

B.  Ribs

C.  Flat bones of the head and Pelvis

D.  Shaft of the long bones

E.  End of the long bones

 

-Which of the following are precursor cells for platelets? A

A.  Megakaryocytes

B.  Rubriblasts                                                      reticulocytes

C.  Myeloblast                                                      granulocytes

D.  Progranulocytes

 

- Differentiation of cells is controlled by?  B

A.  Stem cells

B.  cytokines

C.  erythropoietin

D.  thrombopoietin

 

-Which of the following is a example of an congenital myeloaplastic disorder?  C

A.  HIV

B.  Hep A

C.  fanconi's syndrome

D.  non A hep

 

-Which of the following are examples of myelodysplastic anemia?  C

-Which of the following do you see increased complement in the serum? A

-Which of the following do you see splenomegaly?  B

-Which of the following do you see diminished hematopoiesis? A

-Which of the following do you see abnormal hematopoiesis? B

-Which of the following do you see a dry tap on the bone marrow biopsy?  B

-Which of the following do you see elevated WBC (>100,000)?  B

A.  Paroxysmal Nocturnal Hemoglobinuria

B.  Myelofibrosis

C.  Both

d.  neither

 

-No arterial hypoxia is present in polycythemia rubra vera?A

A.  true

B.  false

 

-Philadelphia choromosome can be present in which of the following? E

-Which of the following is usually seen in kids? A

-Auer rods are present in which of the following? A

-Agranular blasts are present in which of the following? B

-Which of the following is not a disorder of the stem cell?  D

-Which of the following is most common type of leukemia?  D

A.  ALL

B.  AML

C.  CML

D.  CLL

E.  Both A and C

F.  None of the above

 

-Which of the following have phagocytic activity? C

-Which of the following has quicker chemotaxis? A

A.  Neutrophils

B.  Monocytes

C.  All of the above

D.  none of the above

 

- What is the treatment for severe neutropenia? C

A.  Bone marrow transplant

B.  neutogen

C.  reverse isolation of pt.

D.  All of the above

E.  B and C only

 

-Allergic reactions would make the eosinophils increase on a CBC? A

A.  true

B.  False

 

-T cells are stored in which of the following? C

A.  Spleen                                              mainly B cells

B.  vasculature                                     

C.  thymus                                             T cells

D.  liver                 

E.  lymph nodes                                    lymphocytes

 

-Give the appropriate stage for the following non hodgkins lymphoma

lymph nodes regions on both sides of the diaphragm w/ spleen involvement and extralymphatic site,  w/ presence of constitutional symptoms (fever, night sweats, weight loss).  C

A.  IIA

B.  IIIB

C.  IIIesB

D.  IIIesA

E.  IVB

 

-which of the following does not follow anatomic progression? B

-which of the following usually presents w/ asymptomatic lymph node enlargement? A

-which of the following usually have mediastinal mass on chest x-ray?  A

-fever, night sweats, and weight loss can be present in which of the following?  C

-reed sternberg cells are often seen in which of the following?  B

A.  Non hodgkins lymphoma

B.  hodgkins lymphoma

C.  Both

D.  neither

 

-which of the following is malignant disorder of plasma cells? C

-which of the following is IgM malignancy?  B

-which of the following is IgG malignancy? A

-Bence jones proteins are seen in which of the following?  A

A.  multiple myeloma

B.  Waldenstrom's macroglobulinemia

C.  both

D.  neither

 

-Which of the following are lab findings in hemolytic anemia? D

A.  Increased serum LDH

B.  Increased serum HgB

C.  hemoglobinuria

D.  all of the above

 

-which of the following is due to defect in the RBC cytoskeleton?  C

-gall stones are a common finding in which of the following disorders?  C

A.  hereditary spherocytosis

B.  hereditary elliptocytosis

C.  both

D.  neither

 

-splenomegaly is usually NOT present in which of the following disorders?  A

-spike in the S component is present in the which of the following disorders?  C

A.  Sickle cell SS dz

B.  SC dz.

C.  both

D.  neither

 

-In which of the following are blacks more affected?  E

A.  Sickle cell SS dz

B. SC dz.

C.  G6PD deficiency

D.  thalassemias

E.  All of the above

 

-what is the most common cause of acquired hemolytic anemia?  B

A.  dysplastic anemia

B.  immune causes

C.  traumatic causes

D.  toxic causes

 

- In which of the following are Schistocytes seen? E

- Which one of the following do you expect to find a prolonged PT and aPTT? C (all the others have normal PT and aPTT)

A.  TTP

B.  HUS

C.  DIC

D.  Prosthetic valve problems

E.  All of the Above

F.  None of the Above

 

- Target Cells are seen in which of the following?  C

A.  Liver Failure

B.  Thalassemias

C.  All of the above

D.  none of the above

 

- Which of the following dzs. would you expect to have decreased MCV (microcytic anemia)?  D

A.  Chronic immune dz

B.  Vit B12 Deficiency

C.  Folate Deficiency

D.  Thalassemia

 

- Which of the following have findings of megaloblastosis in the bone marrow? C

A.  Folate deficiency

B.  Vit B12 deficiency

C.  All of the above

D.  None of the above

 

- What is the most common cause of Fe loss in adults? D (lack of dietary intake is usually in children)

A.  lack of dietary intake

B.  pregnancy

C.  alcohol abuse

D.  Blood loss 

E.  malabsorption

 

- What one test can tell you if blood loss is acute or chronic? C

A.  UA

B.  Chem 7

C.  reticulocyte count

D.  PT

E.  aPTT

 

- Which of the following cause sideroblastic anemia? E

A.  Delta aminolevulinic acid synthesis Dz.

B.  alcohol

C.  isoniazed

D.  lead

E.  all of the above

 

- In acute blood loss when do you give the pt. RBC transfusion? E

A.  go by the degree of pts. symptoms

B.  when pts HgB gets around 8 mg/dl

C.  if the pt is mildly anemic

D.  If the pt. is hypotensive

E.  Both B and D

 

- In selecting a donor for bone marrow transplant which one of the following would be the best donors? D

A.  siblings

B.  parents

C.  O negative bone marrow

D.  HLA identical twins

 

- In which of the following would bone marrow transplants be indicated?  E

A.  acute leukemia (ALL, AML)

B.  Lymphomas and Multiple myelomas

C.  severe aplastic anemia

D.  genetic dzs. (sickle cell SS, thalassemia, breast CA)

E.  all of the above

F.  none of the above 

 

- Which of the following gives us an indication on the function of the extrinsic pathway? D

A.  CBC

B.  peripheral smear

C.  bleeding time

D.  PT

E.  aPTT

- the bleeding time is prolonged in which of the following?  D

A.  thrombocytopenia

B.  qualitative platelet defects

C.  von Willebrand dz.

D.  All of the above

E.  none of the above

 

- All of the following can cause a decrease in platelet production except? B (heparin causes an increase in destruction)

A.  Chemo/Radiation therapy

B.  Heparin

C.  Vit B12 deficiency

D.  thiazide diuretics

E.  all of the above cause a decrease in platelet production

 

-  Which of the following is caused by problems w/ factor 8? C

-  bleeding time is prolonged in which of the following? A

-  aPTT will be prolonged in which of the following?  D

A.  von willebrand dz

B.  hemophilia A

C.  hemophilia B

D.  Both A and B

E.  All of the Above

 

- which of the following subtypes is most severe form of  von willebrand dz.?  C

A.  type 1

B.  type 2

C.  type 3

D.  type 4

 

-which of the following is involved in secondary hemostasis? C

- which of the following results in amplification of secondary hemostasis? A

- which of the following results in the initiation of secondary hemostasis? B

A.  Intrinsic Pathway

B.  Extrinsic Pathway

C.  both

D.  neither

 

- which factor is not involved in the intrinsic pathway? A

A.  factor 7

B.  factor 8

C.  factor 5

D.  factor 9

 

- which of the following is the major site for the synthesis of most coagulation proteins? C

A.  Spleen

B.  thymus

C.  liver

D.  bone marrow

E.  kidneys

 

- which of the following is not affected by liver Dz?  B

A.  factor 7

B.  factor 8

C.  factor 9

D.  factor 10

E.  factor 2

 

-which of the following results from factor 9 deficiency?  B

A.  Hemophilia A

B.  Hemophilia B

C.  von Willebrand dz.

 

-what lab finding is the hallmark for vit K deficiency? C

A.  prolonged bleeding time

B.  TCT

C.  Prolonged PT

D.  None of the above

 

-TPFI neutralizes which factor? C

A.  factor 2                            ATIII

B.  factor 5                             Pro C

C.  factor 7                             TPFI

D.  factor 8                             Pro C

E.  factor 9                             ATIII

 

-Which of the following would be used in acute situations?  A

-Which of the following block regeneration of vit K?  B

-Which of the following work on factors 2,9,10? C

-Which of the following would have a prolonged PT? B

-Which of the following would have a prolonged aPTT? A

-Which of the following work by activating plasminogen to plasmin?  D (TPA, Streptokinase)

A.  Heparin

B.  Warfarin

C.  Both

D.  neither

 

-What risk do you take when putting a pt. on TPA or streptokinase? B

A.  MI

B.  Stroke

C.  Kidney failure

D.  Hepatotoxic

 

- What is the most common cause of death in the US? C

A.  accidents

B.  Cancer

C.  cardiovascular dz.

D.  stress

 

- What is the most abundant enviornmental carcinogen? A

A.  Tobacco

B.  Asbestos

C.  coal

D.  Mold