The dosages that are effective in treating these cravings and dependences have varied in different articles and studies, some saying 500-800mg of ibogaine, some saying 15 to 20 mg/kg.
When patients do take the recommended dosage, the withdrawl symptoms of these drugs is said to diminish from within the time it is digested to 45 minutes after it is digested. Once the ibogaine is administered, the effects, which are supposedly dream-like and visualization of various things, last from 8 hours to 20 hours with sometimes two days of recovery after the effects (Lotsof and Wachtel).
After the first time of digestion, the patient will need to take ibogaine daily in various dosages, usually depending on the strenghth of the dependency of the original drug and what the doctor feels will work the best. These dosages are usually much less than the original dose.
Studies have shown that ibogaine has the normal effects on the CNS as many hallucinogens, as well as effecting dopamine releasing neurons. Ibogaine has shown that it effects this dopamine system by lowering the effects of psychotropic drugs upon this system (Carlini, 506).