Steroids chemistry
It is important while reading this to remember that my perspective on bodybuilding will undoubtedly effect the way I present this information. steroids chemistry Steroids and women. I do not in any way condone cheating to win a contest, or breaking state or federal laws to accomplish your goals. Instead, I am simply sharing knowledge with current, or potential, users with appropriate access to anabolic substances. The GH/IGF-1 AxisYour body's GH levels are tightly regulated by numerous chemical messengers including macronutrients, neurotransmitters, and hormones. steroids chemistry Anabolic discussion boards. The signal to increase your body's GH levels starts in the hypothalamus. There, two peptide hormones act in concert to increase or decrease GH output from the pituitary gland. These hormones are somatostatin (SS) and growth hormone- releasing hormone (GHRH). steroids chemistry Anabolic frolic. Somatostatin acts at the pituitary to decrease GH output. GHRH acts at the pituitary to increase GH output. Together these hormones regulate, in pulsatile fashion, the level of GH you have floating around in your body (see Fig. 1). Several factors can effect this delicate balance. First, GH is subject to negative feedback in response to its own release. GH, as well as IGF-1, circulate back to the hypothalamus and pituitary to increase SS release, thereby decreasing GH release. GH may also act in an autocrine and paracrine (i. e. Effecting the source cells and neighboring cells without having to enter the circulation) fashion within both the hypothalamus and pituitary. Neurotransmitters also effect GH levels at the hypothalamus. This neuroendocrine control is still being elucidated but some factors are already clearly involved (see table 1). Table 1. Neurotransmitter systemEffect on GHNeurotransmitter or drugAdrenergica2a1� IncreaseDecreaseDecrease ClonidineMethoxamineClenbuterolCholinergicIncreaseAcetylcholineOpioidsIncreaseMorphineDopamineIncreaseL-DopaGut-brain peptidesIncrease Nutrition and metabolic factors also modulate GH levels. A fall in blood glucose such as during exercise or during sleep causes an increase in GH secretion. High protein feedings increase acute GH secretion. Some amino acids such as L-arginine seem to increase GH by decreasing SS release from the hypothalamus. Even the vitamin Niacin has been shown to increase exercise induced GH release by 300- 600%(Murray, 1995).
Steroids chemistry
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