C.1997.082      Prevalence of Colonic Adenomas in          Lawitz                Kadakia, Shailesh   Department of          Ongoing                  4 Dec 00  1 Nov 01

                    Average Risk Asymptomatic Patients on                                                    Medicine,

                    Daily Aspirin                                                                                     Gastroenterology

                                                                                                                        Service

C.1998.071      Pilot Study to Determine if Proton Pump      Rensch               Morris, Parker,       Department of          Ongoing                   3 Oct 01  1 Sep 02

                    Inhibitor Therapy Improves Asthmatic                                                        Medicine,

                    Patients in Those with Exercise-Induced                                                    Gastroenterology

                     Asthma                                                                                          Service

  C.1998.074     Intron AR+Ribavirin for treatment of          Lawitz                Shaffer R,            Department of          Ongoing -                  11 Jul 01  1 Jun 02

                    patients with chronic hepatitis C not                                                         Medicine,                CTNPA

                    previously treated with Interferon                                                            Gastroenterology

                                                                                                                        Service

C.1998.101e     Use of Multistix Leukocyte Esterase         Butani                 Shaffer,              Department of          Ongoing                   8 Feb 01  1 Jan 02

                    Dipstick Testing for Ascitic Fluid                                                              Medicine,

                    Infection                                                                                          Gastroenterology

                                                                                                                        Service

  C.1999.039     A Multi-Center Randomized Trial              Lawitz                Kadakia S            Department of          Ongoing -                  11 Jul 01  1 Jun 02

                    Comparing Daily Induction Dose Intron-A                                                    Medicine,                CTNPA

                     Plus Ribavirin Followed by Daily                                                              Gastroenterology

                    Rebetron Vs Standard Rebetron in                                                           Service

                    Patients with Chronic Hepatitis C Who

                    Have Not Previously Been Treated with

                    Interferon

  C.1999.099     A Multicenter Study Evaluating the           Lawitz                Kadakia               Department of          Ongoing -                  8 Feb 01  1 Jan 02

                    Efficacy of Induction Interferon Plus                                                         Medicine,                CTNPA

                    Ribavirin Followed by Daily Interferon                                                        Gastroenterology

                    and Ribavirin for the Treatment of                                                            Service

                    Chronic Hepatitis C

C.2000.001      Study to Determine the Incidence of          Rensch               Fink, S                Department of          Ongoing                  1 Aug 01  1 Jul 02

                    Celiac Disease in Patients with Seizure                                                      Medicine,

                    Disorder                                                                                          Gastroenterology

                                                                                                                        Service

  C.2000.005     A Randomized Multicenter Trial               Lawitz                Kadakia               Department of          Ongoing                  1 Aug 01  1 Jul 02

                    comparing Induction PEG Intron-A plus                                                      Medicine,

                    Ribavirin versus PEG Intron-A plus                                                           Gastroenterology

                    Ribavirin in Patients Who have                                                                Service

                    Previously Not Responded or Have

                    Relapsed Following Intron-A Based

                    Therapy for Chronic Hepatitis C, with

                    Maintenance Therapy for Patients who

                    Continue to Remain Non-Responsive

  C.2000.021     A Comparison Study of the Effect on        Wolff                  Shaffer,              Department of          Ongoing                  5 Sep 01  1 Aug 02

                    Gastric Tissue Prostaglandin Levels                                                         Medicine,

                    and Gastroduodenal Injury in                                                                  Gastroenterology

                    Placebo-Controlled Trial of                                                                     Service

                    Cyclooxygenase 2 Inhibitors as

                    Compared with Traditional Non-steroidal

                     Anti-inflammatory drugs (Naproxen)

  C.2000.043     The Use of Celecoxib, a                        Sears                 Shaffer R, Levine   Department of          Ongoing                  11 Jan 01  1 Dec 01

                    Cyclooxygenase-2 Inhibitor, for the                                                          Medicine,

                    Treatment of Duodenal Adenomas in                                                         Gastroenterology

                    FAP Patients                                                                                     Service

  C.2000.135     Multicenter Randomized Open Label         Hepburn              MAJ Eric Lawitz,    Department of          Ongoing -                  2 May 01  1 Apr 02

                    Study of the Safety and Efficacy of                                                          Medicine                 CTNPA

                    Interferon Alpha-2b plus Ribavirin for the

                    Treatment of HCV Infection in

                    HIV-Infected Persons: Daily versus TIW

                    Interferon Dosing

  C.2000.139     Induction Intron-A + Ribavirin Followed      Lawitz                Kadakia S            Department of          Ongoing                   6 Jun 01  1 Jun 01

                    by Daily Rebetron +/- Amantadine in                                                         Medicine,

                    Patients Who Have Previously Not                                                            Gastroenterology

                    Responded or Have Relapsed Following                                                    Service

                    Intron-A Based Therapy for Chronic

                    Hepatitis C: A Randomized Multicenter

                    Trial

C.2000.175      Simvistatin in the Treatment of                Harrison              Kadakia, Koops,     Department of          Ongoing                  1 Aug 01  1 Jul 02

                    Nonalcoholic Steatohepatitis                                                                  Medicine,

                                                                                                                        Gastroenterology

                                                                                                                        Service

  C.2000.176     The Comparison of PEG Interferon           Lawitz                Kadakia S            Department of          Ongoing                  1 Aug 01  1 Jul 02

                    Alfa-2b and Two Different Doses of                                                         Medicine,

                    Ribivarin for Treatment of Chronic                                                            Gastroenterology

                    Hepatitis C in Previously Untreated Adult                                                    Service

                     Subjects

  C.2001.005     Endoscopic Consequences After            Hurley                LtCol Young,         Department of          Ongoing                  5 Sep 01  1 Aug 02

                    Transesophageal Echocardiography                                                        Medicine,

                                                                                                                        Gastroenterology

                                                                                                                        Service

C.2001.017      Vitamin E and Vitamin C in the                 Harrison                                      Department of          Ongoing                  1 Nov 01

                    Treatment of Nonalcoholic                                                                     Medicine,

                    Steatohepatitis (NASH)                                                                        Gastroenterology

                                                                                                                        Service

  C.2001.047     A Randomized Multicenter Trial of            Lawitz                                        Dept of Medicine,       Ongoing                  1 Dec 01

                    PEG-Interferon Alfa 2b plus Ribivarin +/-                                                    Gastroenterology

                    Amantadine In Patients With Chronic                                                         Service

                    Hepatitis C

  C.2001.064     A Randomized, Crossover Comparison      Jones                 COL S. Kadakia     Department of          Ongoing                   1 Jan 02

                    of Once Daily Pantoprazole versus                                                          Medicine,

                    Omeprazole b.I.d. in the Suppression of                                                     Gastroenterology

                    Gastric Acid in Patients with GERD                                                          Service

C.2001.168      A 12-Month Course of Body                   Lawitz                                        Department of          Needs CIRO                 1 Jul 02

                    Weight-based PEG-Intron Monotherapy                                                      Medicine,                Approval/Revie

                    or Combination with Lamivudine for                                                          Gastroenterology      w

                    Treatment of Chronic Hepatitis B                                                             Service

  C.2001.175     Orlistat (Xenical) in the Treatment of         Harrison              LtCol Paul             Department of          Needs CIRO               1 Aug 02

                    Nonalcoholic Steatohepatitis (NASH)                                                        Medicine,                Approval/Revie

                                                                                                                        Gastroenterology      w

                                                                                                                        Service

  c.2001.178     Interleukin-11 in Patients with chronic        Lawitz                                        Department of          Needs CIRO               1 Aug 02

                    Hepatitis C with Advanced Liver Disease                                                   Medicine,                Approval/Revie

                     Who Have Been Nonresponsive to                                                          Gastroenterology      w

                    Antiviral Therapy - A Pilot Study                                                              Service

C.2001.179      Comparison of Dry Versus Wet Injection    Dantzler                                      Department of          Needs CIRO               1 Aug 02

                    Technique for Subcutaneous                                                                 Medicine,                Approval/Revie

                    Administration of PEG-Interferon Alfa-2b                                                    Gastroenterology      w

                                                                                                                        Service

  C.2001.180     Use of Methylene Blue for Detection of      Vinson                                        Department of          Needs CIRO               1 Aug 02

                    Intestinal Metaplasia in Patients with                                                         Medicine,                Approval/Revie

                    Suspected Barrett's Esophagus                                                              Gastroenterology      w

                                                                                                                        Service

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