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Sarah MacKinnon
Employment
1998-1999 Pharmacy Technician, Medical College of Virginia Hospitals, Richmond, VA.
1999- 2000 Student Assistant, Department of Biochemistry and Molecular Biophysics, Medical College of Virginia of Virginia Commonwealth University, Richmond, VA. Dr. Robert K. Yu and Dr. Erhard Bieberich Projects: Regulation of ganglioside expression by post-translational modification and subcellular localization of glycosyltransferases. Drug treatment approaches to mucopolysaccharidosis IIID (sanfillippo disease).
Summer 2000 Student Assistant, Neurobiology, Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA. Dr. Robert K. Yu and Dr. Erhard Bieberich Projects: Regulation of ganglioside expression by post-translational modification and subcellular localization of glycosyltransferases. Induction of sphingolipid-mediated cell death in mitotic cells of the nervous system. Novel ceramide analogs as anti-cancer drugs inducing apoptosis in tumor cells.
2000-2001 Student Assistant, Department of Neurosurgery, Medical College of Virginia of Virginia Commonwealth University, Richmond, VA. Dr. William Broaddus and Dr. Helen Fillmore Project: Radiosensitization of malignant gliomas by viral transduction with wild-type p53.
Summer 2001 Student Assistant, Neurobiology, Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA. Dr. Robert K. Yu and Dr. Erhard Bieberich (also collaborative efforts with Drs. William Broaddus and Dr. Helen Fillmore) Projects: Regulation of ganglioside expression by post-translational modification and subcellular localization of glycosyltransferases. Induction of sphingolipid-mediated cell death in mitotic cells of the nervous system. Novel ceramide analogs as anti-cancer drugs inducing apoptosis in tumor cells.
2001- 2002 Student Assistant, Molecules For Health, Inc. Virginia Biotechnology Research Park, Richmond, VA. Dr. Howard Elford (and collaborative efforts with Dr. William Soine at the Department of Medicinal Chemistry at Medical College of Virginia of Virginia Commonwealth University, Richmond, VA) Projects: Synthesis of inhibitors of ribonucleotide reductase. Pharmacokinetics of ribonucleotide reductase inhibitors. Anti-tumor and anti-viral effects of ribonucleotide reductase inhibitors. |
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