Dr. R. P. Tripathi’s Home Page
The Group:
Ram Chandra Mishra (SRF)
Neetu Tewari (RS)
Diksha Katiyar (RS)
Shyam Sunder Verma (RS)
Namrata Dwivedi (JRF)
Vinod Kumar Tiwari (March 2000-Feb 2004, Joined Universiy of Jhanshi As Lecturer)
V.K.Maurya
(Technician)
BIODATA OF DR. R.P.TRIPATHI
Name : Dr. R.P.Tripathi
Date of Birth : 24.12.1956
Designation : Scientist EI1. Astt. Director
Postal Address : Medicinal Chemistry Division
Central Drug Research Institute,
Chattar Manzil Palace
Lucknow-226001
Phone No.(0522) 2212411-418 Extn. 4462
(0522) 2710421(Residence)
Educational Qualifications:
|
Degree |
University |
Year |
Division |
Field |
|
Ph.D. |
Delhi University |
1985 |
-- |
Organic Chemistry |
|
M. Phil |
Delhi University |
1982 |
A Grade |
Organic Chemistry |
|
M.Sc. |
Gorakhpur University |
1979 |
Ist |
Chemistry |
|
B.Sc. |
Gorakhpur University |
1977 |
Ist |
Biological Sciences |
Positions held:
JRF UGC New Delhi 1981-1983
SRF UGC New Delhi 1983-1985
Research Associate NIH project at CDRI, Lucknow 1985-1987
Scientist B CDRI, Lucknow 1987-1992
Scientist C CDRI, Lucknow 1992-1997
Scientist E1 CDRI, Lucknow 1997-2001
Scientist EII CDRI, Lucknow 2001 till
date
Membership of scientific bodies:
Life member Indian Chemical Society
Life member Indian medicinal chemists association
Life member UP association of advancement of science and technology
Life member Society of biological chemists of India
Member of Association of Carbohydrate Chemists & Technologists of India
Editorial Board member of Chemistry –An Indian Journal
6.Research and training Experience:
20 years reseach experience in different laboratories of Delhi University and Central
Drug Research Institute, Lucknow.
7. Research Specialisation:
Medicinal Chemistry, Bio-Organic Chemistry, Synthetic
Chemistry, Combinatorial Chemistry
8. List of Publications :
During Ph D
1. A convenient synthesis of propyl substituted benzofuro coumarins. V.K. Ahluwalia, R.P. Singh, R. P. Tripathi, Heterocycles (1984), 22(12), 2783.
2. A novel synthesis of 4-propyl –2H-1-benzopyran-2-ones. V.K. Ahluwalia, R.P. Singh, R.P. Tripathi, Montash fur chemie (1984), 115), 765.
3. An efficient synthesis of 4-propylpyranocoumarins. V.K. Ahluwalia, R.P. Singh, R.P. Tripathi, Gazzeta Chimica. Italiana (1984), 114, 505.
4. An elegant synthesis of 6-butyryl chromans and chromenes. V.K. Ahluwalia, R.P. Singh, R.P. Tripathi, Gazzeta Chimica. Italiana (1984), 114, 359.
5. A facile synthesis of 4-propyl psoralen and angellicine derivatives. V.K. Ahluwalia, R.P. Tripathi, J. I ndian Chem Soc. (1984), LXI, 1023.
Year 1987-1994:
6. Studies in nucleosides: PartXVII: Synthesdis of 4-amino-6-methoxy pyrazolo{3,4-d] pyrimidine and 4-amino-6-methylthio pyrazolo[3,4-d]pyrimidine ribosides and their antiviral activities. R.P. Tripathi, A.Hasan, Ram Pratap and D.S. Bhakuni, Indian J. Chem. (1987), 26B, 851.
7. Studies in nucleosides: PartXIX: Synthesdis of 4,6-disubstituted derivatives of 1-a-D-arabinofuranosylpyrazolo{3,4-d] pyrimidines and their antiviral activities. R.P. Tripathi, Ram Pratap and D.S. Bhakuni, Indian J. Chem. (`1987), 26B, 1054.
8. Studies in nucleosides: PartXX: Synthesis and antileishmanial activities of 4-oxo-(5H)- pyrazolo{3,4-d] pyrimidine-a & b-nucleosides. A Hasan, R.P. Tripathi, Ram Pratap and D.S. Bhakuni , Indian J. Chem. (`1989), 28B, 403.
9. Synthesis of 1/2-benzyl-4,6-disubstituted –1H/2H-pyrazolo(3,4-d)-pyrimidines and their antileishmanial activities. A. Mishra, L. M. Ojha, R. P. Tripathi, R. Pratap and D.S. Bhakuni. Indian J. Heterocyclic Chem. (1991), 1, 51.
10. 3-Cyano-4-methyl-5-vinyl pyridine: A potent synthetic hepatoprotective agent. P.K.S. Visen, Binduja Saraswat, G.K. Patnaik, R.C. Srimal, R.P. Tripathi and D.S. Bhakuni. Indian J. Pharmacol. (1993), 25, 149.
11. Glutathione-S-trasferase activity in S. cervi females and effect of new antifailarial compounds. A.K. Srivastava, R. P. Tripathi, A.R. Khan, A.P. Bhaduri, S. N.Singh and R.K. Chatterjee. Indian J. Parasitology (1994), 46, 169.
Year 1995:
12. Effect of 3-O- (aminoalkyl)- a-D-gluco (xylo) furanoses on glutathione metabolism of falarial parasites. A.K. Srivastava, R. P. T ripathi, A. R. Khan, A. P. Bhaduri, S.N.Singh and R.K. Chatterjee, Helminthologia (1995), 32, 25.
13. Synthesis and antiviral activities 3-O-(aminoalkyl)-1,2-O-isopropylidene-a-D-gluco-(xylo)furanoses, R.P.Tripathi, V. Singh, A.R. Khan , A.P. Bhaduri, G. Saxena and K. Chandra. Indian J Chem. (1995), 34B, 791.
14. Effect of glucofuranose ring in the asymmetric induction to the appended side chains. R. P. Tripathi, A.R.Khan, A.P. Bhaduri, S. Bhatnagar and A. K. Srivastava, “Trends in carbohydrate chemistry,” edited by P.L.Soni, Surya International Publication, Dehradune pp 1-4 (1995).
Year 1996:
15. Synthesis of 2,3-anhydronucleosides of pyrazolo(3,4-d) pyrimidine as antiviral agents. R.P.Tripathi, Anil Mishra, Ram Pratap and D.S.Bhakuni, Indian J. Chem. 35B, 441,(1996).
16. Asymmetric induction in the epoxidation of 3-and 5-O-allyl glycofuranoses with mCPBA. A.R.Khan, R. P. Tripathi and A.P. Bhaduri, Indian J. Chem. 35B, 405, (1996).
17. Synthesis and spermicidal activities of dithiocarbamates, R.P. Tripathi, A.R.Khan, B.S.Shetty and A.P. Bhaduri, Acta Pharmaceutica, 46, 169, (1996).
Year 1997-2000:
18. Hepatoprotection by 3-cyano-5-ethenyl-4-methyl pyidine (compound 89/62) against experimentally induced liver injury in rats. S. Srivastavs,S.C.Tripathi, A.K.Srivastava,D.S.Bhakuni, R. P. Tripathi and G.K.Patnaik, Acta Pharmaceutica, 47, 1997, 117.
19. Cabohydrates in biological recognition, A.R.Khan, R. P. Tripathi and A.P.Bhaduri, Biol. Memoirs. 23(2), (1997), 73.
20. a-Cyano ethyl propenoates: a new class of antileishmanial agents. S. Tewari, R. P. Tripathi, A.R.Khan, S.Gupta, J.C.Katiyar and A.P. Bhaduri, Arzen Forsch/ Drug Res. , 1999, 49(I), 144-148.
21. DNA Topoisomerases of filarial parasites:Effect of antifilarial compounds. U.Pandya, J.K.Saxena, S.M.Kaul, P.K.Murthy, R.K.Chatterjee, R .P. Tripathi, A. P. Bhaduri and O. P. Shukla, Medical Science Res., 1999, 27, 103-106.
22. Antifilarial activity of 2H-1-Benzopyran-2-ones (coumarins), R. P. Tripathi, R. Tripathi, S. N. Singh, A. P. Bhaduri, R. K. Chaterjee and Kalpana Murthy, Acta Tropica, 2000,76, 101-106.
Year 2001:
23. Synthesis and
antiviral activity of 3-O-(2'-hydroxy aminopropyl)- α
-D-glucofuranoses, N. S. Rana, P. Gupta,
24. Synthesis and immunomodulatory activities of 2'-hydroxy-3'-N, N-Disubstituted aminopropyl-α-D-glucofuranoses as immunomodulators: A. R. Khan, R. P. Tripathi, A. P. Bhaduri, R. Sahai, A.Puri, L. M. Tripathi and V. M .L Srivastava, Eur. J. Med. Chem, 2001, 36, 103-106.
25. Identification of inhibitors of DNA Topoisomerase-II from a synthetic library of glycoconjugates, R..P. Tripathi, S. K. Rastogi, B. Kundu, J. .K. Saxena, V. .J. M. Reddy, S. Srivastava, S. Chandra, and A.P. Bhaduri, Combi. Chem. & Highthroughput Screen., 2001, 4, 237-244
26. Study on the loading and reactions of naked sugars on solid phase R. C. Mishra and R. P. Tripathi, Medicinal Chemistry Research, 2001, 10, 548.
27. Glycosyl amino acid derivatives as inhibitors of yeast DNA topoisomerase-I Pooja Jain, Z.K. Khan, R.P.Tripathi and B.L.Tekwani, Abstract of the symposium CTTDDR published in Medicinal Chemistry Research, 2001, 10, 550.
Year 2002:
28. Synthesis of Glycosylated b-amino acids as new class of antitubercular agents R. P. Tripathi, R. Tripathi, V. K. Tiwari, Laxmi Bala, S. Sinha, A. Srivastava, R. Srivastava, B. S. Srivastava, Eur. J. Med. Chem , 2002, 37, 773-781.
29. Unexpected Isomerisation of Double bond with DBU: A Convenient Synthesis of Tetrasubstituted a-alkylidene tetrahydrofuranoses V. K. Tiwari and R. P. Tripathi, Indian J. Chem, 2002, 41B, 1681-1685.
30. Conjugate Addition of Amines to Sugar Derived Olefinic Ester: Synthesis of Glycosylated Amino Esters as DNA Topoisomerase –II Inhibitors, A.R.Khan, R.P. Tripathi, V.K.Tiwari, R.C. Mishra, V.J.M.Reddy and J.K.Saxena, J. Carbohydrate Chemistry, 2002, 21(6), 591-604.
31. DBU/ TBAB/4A0 Catalysed cyclatic amidation reactions: A highly efficient & convenient synthesis of C-Nucleosides. N. Tewari, R.C. Mishra, V.K.Tiwari, R.P.Tripathi, SYNLETT, 2002, No11, 1779-1782.
32. Depletion of intracellular glutathione of S.cervi by Buthionine sulphoximine, carmustine and their analogs, S. Gupta, R.P.Tripathi, A.K. Srivastava and J. Iqbal Proceedings of the 6th World Multiconference on Systemics, Cybernetics and Informatics Proceedings, Industrial Systems and Engineering III, 2002, XVII, 491-496.
Year 2003:
33. 7-O-(4-methyl piperazin-acetyl)-4-methyl-2H-1-benzopyran-2-ones: A novel lead compound for antifilarial activity, R. P. Tripathi, V. K. Tiwari, S. Bhattacharya, K. Srivastava, V. M. L. Srivastava and K. Murty, Acta Tropica, 2003, 87, 215-224.
34. DBU Assisted Cyclorelease Elimination: Combinatorial Synthesis and g-glutamyl cystein synthetase & glutathione-S- transeferase Modulatory Activity of C- nucleoside anlogs R.C. Mishra, Neetu Tewari, Kavita Arora, Rumana Ahmad, R. P. Tripathi, V.K.Tiwari, R. D. Walter and A.K. Srivatava, Combi Chem & Highthroughtput Screening, 2003, 6, 37-51.
35. Synthesis and Antifilarial Evaluation of N1, Nn- Diglycosylated Diaminoalkanes, V. K. Tiwari, Neetu Tewari, Diksha Katiyar, R.P. Tripathi, Kavita Arora, Sapna Gupta, A. K Srivastava, M. A. Khan and P. K. Murthy, Bio-Org. & Med. Chem., 2003, 11, 1789.
36. Synthesis and antifilarial evaluation of 7-O-acetamidyl-4-alkyl-2H-1-benzopyran-2-ones: D.katiyar, V.K.Tiwari, R.P.Tripathi, V.J.M.Reddy, S. Bhattacharya, J.K.Saxena Arzn. Forsch/Drug Research , 2003, 53(12), 857-863.
37. Synthesis and bioevaluation of glycosyl ureas as a-glucosidase inhibitors and their effect on Mycobacterium: Neetu Tewari, V.K. Tiwari, R.C. Mishra, R.P. Tripathi, A.K.Srivastava, R. Ahmad, R. Srivastava and B.S.Srivastava, Bioorg. Med. Chem., 2003, 11, 2911-2922.
38. Amberlite IR -120 Catalysed Efficient Synthesis of Glycosyl Enaminones and their Application, Neetu Tewari, Diksha Katiyar, Vinod Kumar Tiwari and Rama P. Tripathi Tetrahedron Lett., 2003, 44, 6639-6642.
39. Synthesis and Antimycobacterial Activity of 3,5-Disubstituted Thiadiazine thiones, D Katiyar, V. K. Tiwari, R. P. Tripathi, A. K. Srivastava, V. Chaturvedi, R. Srivastava and B. S. Srivastava , Bio. Med. Chem., 2003, 11, 4369-4375.
40. Synthesis of Glycosylated β-Amino Hydroxamates As New Class of Antimalarials, R.C.Mishra, Renu Tripathi, Diksha Katiyar, Neetu Tewari, Deepti Singh, and R.P.Tripathi Bio. Med. Chem., 2003, 11, 5363-5374.
Year 2004:
41. 4-Methyl-7- (tetradecanoyl)-2H-1-benzopyran-2-one: A novel DNA topoisomerase II inhibitor with adulticidal and embryo static activity against sub periodic Brugia malayi Shailja Misra-Bhattacharya, Diksha Katiyar, R.P. Tripathi and J.K. Saxena, Parasitalogy Research, 2004, 92(3), 177-184
42. A versatile synthesis of Dihydropyrimidinone C-nucleosides, Ram Chandra Mishra, Diksha Katiyar, Neetu Tewari and R.P. Tripathi, Nucleosides, Nucleotides and nucleic Acid , 2004, 23 (3), 531-544
43. Diastereoselective Synthesis of Galactopyranosyl Amino Esters and their Transformations into C-nucleosides, Diksha Katiyar, Ram Chandra Mishra and Rama Pati Tripathi, Journal of Carbohydrate Chemistry, 2004, 23 (1), 49-70.
44.
Search for new antitubercular agents: SPOS of
Glycoconjugates on Sieber Amide resin, R. P. Tripathi, R. C. Mishra, Diksha Katiyar,
K.K. Srivastava, R. Srivastava, B.S. Srivastava, Revised manuscript submitted
to Ind. J. Chem, 2004.
45. Synthesis of
Galactopyranosyl Amino Alcohols as a new class of Antitubercular and antifungal agents, Neetu Tewari, V.K.
Tiwari, R. P. Tripathi, A. Gaikwad, S. Sinha, P K
Shukla, R. Srivastava and B. S. Srivastava, Bio. Med. Chem.Lett., 2004, 12, 329-332.
46. An efficient
syntheses of a-mannosylated
phenolics as a-glycosidase
inhibitors, Khan A.R., Tiwari V.K. , Srivastava
A.K.Tripathi R.P., J. Enzyme Inhibition 2004, 19(2), 107-112.
47. Potential
Inhibitors of DNA topoisomerase-II: ruthenium (II) poly-pyridyl and pyridyl-azine complexes Manish Chandra, A.N.
Sahai, D.S.P andey, R.P. Tripathi, J.K. Saxena, V.J.M. Reddy, M. Carmen Peutra,
Pedro Valerga J. Organometallic Chemistry 2004, 689, 2256-2267.
48. 1,3 Dipolar Cycloaddition of Glycosyl Nitrile Oxides with Alkenes: Diastereoselective Synthesis of Glycosyl Isoxazoles, R.C. Mishra, Neetu Tewari, S. S. Verma and R.P. Tripathi , J. Carbohydr. Chem. 2004, ( In Press)
49. Phenylene bridged bis -glycosyl ureides as potential antileishmanial agents, Neetu Tewari, Ramesh, R. C. Mishra, Suman Gupta and R. P Tripathi, Bioorg. Med. Chem.Lett. 2004 (In press).
50. Fighting Tuberculosis: An old disease with new challenges, Neeetu Tewari, Namrata dwivedi, V. K. Tiwari, R. P. Tripathi, Medicinal Res. Review, 2004, ( In press).
51. Tetrabutyl Ammonium Hydrogen Sulphate Catalysed Efficient Synthesis of Glycosyl Dihydropyrimidinones. Namrata Dwivedi, Ram C. Mishra and Rama P.Tripathi. (Communicated, CDRI Communication No.6557)Tetrahedron Lett., 2004.
52.
Solid phase synthesis of cyclopropyl phenyl methanones,
Rajesh K. Grover, Ram C. Mishra,
B. Kundu, R.P.Tripathi and R. Roy. (Communicated, CDRI
Communication No. 6442)Tetrahedron Lett., 2004.
53.
Glutathione synthesis in filarial worms: an
attractive target for the design and synthesis of new antifilarials. Kavita
Arora, R.C. Mishra, R.P.
Tripathi, Arvind K.Srivastava, Rolf D. Walter. (Communicated, CDRI
Communication No. 6556) Med. Chem Res., 2004.
54. Phenylene
Bridged Bis -Glycosyl Ureides as Potential Antileishmanial Agents Neetu Tewari, Ramesh, Suman Gupta and R. P Tripathi Medicinal
Chem Res. (Abstract, 2004, In press)
55. Combinatorial
Synthesis of library of glycopeptide analogs: search for new antitubercular
activity R.C.Mishra, V.
K. Tiwari and R.P.Tripathi. Medicinal Chemistry Research, 2003, 12
(6/7), 336. In Second International Synposium on Current Trends in Drug
Discover Research, at Central Drug Research Institute, February 17-20, 2004.
56. Combinatorial and conventional synthesis of glycohybrid molecules as new class of antitubercular agents V. K. Tiwari, R. P Tripathi, V. Chaturvedi, A. Srivastava, S. Sinha, R. Srivastava, and B. S. Srivastava Medicinal Chem Res. (Abstract 2004, In press)
57. Stereoselective Synthesis of nitrogen bridged disaccharides S.S.Verma, R.C.Mishra, and R. P.Tripathi. Medicinal Chemistry Research, 2003, 12 (6/7), 359. In Second International Synposium on Current Trends in Drug Discover Research, at Central Drug Research Institute, February 17-20, 2004.
58. Diastereoselective Synthesis of galactopyranosyl amino alcohols: development of new antitubercular agents Diksha Katiyar and R.P. Tripathi Medicinal Chem Res (Abstract 2004, In press)
59. Search of new prototypes for chemotherapy of filariasis: Chemotherapeutic and biochemical approach. Shailja Misra-Bhattacharya, Preeti Bajpai, Shailendra Kumar Verma, Diksha Katiyar, R.C.Mishra, R. P. Tripathi, Iti Bansal and J. K. Saxena. Medicinal Chemistry Research, 2003, 12 (6/7), 332. In Second International Synposium on Current Trends in Drug Discover Research, at Central Drug Research Institute, February 17-20, 2004.
60. Glutathione synthesis in filarial worms: An attractive target for the design and synthesis of new antifilarials. Kavita Arora, R.C.Mishra, R. P.Tripathi, Arvind K. Srivastava, and Rolf D. Walter Medicinal Chemistry Research, 2003, 12 (6/7), 295. In Second International Synposium on Current Trends in Drug Discover Research, at Central Drug Research Institute, February 17-20, 2004.
List of Patents filed or in process:
1. A process for the synthesis of a & b- isomers of 6-amino-4-oxo-(5H)- pyrazolo{3,4-d] pyrimidine-a & b-nucleosides. Patent in India No. 173563
2. A novel combinatorial library of 3-substituted amino-3-glycosylated propanoates useful as antifungal and antibacterial agents. Rama Pati Tripathi, Praveen Kumar Shukla, Sudhir Sinha, Ranjana Srivastava, Kishor Kumar Srivastava, Vinita Chaturvedi, Anil Srivastava, Brahm Shankar Srivastava. (NF / 451 / 01)
3. A process for the preparation of novel combinatorial library of 3-substituted amino-3-glycosylated propanoatess useful as antifungal and antibacterial agents. Rama Pati Tripathi, Bijoy Kundu, Praveen Kumar Shukla, Sudhir Sinha, Ranjana Srivastava, Kishor Kumar Srivastava, Vinita Chaturvedi, Anil Srivastava, Brahm Shankar Srivastava. (NF / 315 / 01)
4. A process for the preparation of novel combinatorial library of 3-substituted amino-3-glycosylated propanamides useful as antifungal and antibacterial agents. Rama Pati Tripathi, Bijoy Kundu, Praveen Kumar Shukla, Sudhir Sinha, Ranjana Srivastava, Kishor Kumar Srivastava, Vinita Chaturvedi, Anil Srivastava, Brahm Shankar Srivastava. (NF / 151 / 01)
5. A novel combinatorial library of 3-substituted amino-3-glycosylated propanamides useful as antifungal and antibacterial agents. Rama Pati Tripathi, Praveen Kumar Shukla, Sudhir Sinha, Ranjana Srivastava, Kishor Kumar Srivastava, Vinita Chaturvedi, Anil Srivastava, Brahm Shankar Srivastava. (NF / 476 / 01)
6. A process for the preparation of novel N1, Nn-diglycosylated diamino alkanes useful as inhibitors of parasitic enzymes. Rama Pati Tripathi, Vinod Kumar Tiwari, Arvind Kumar Srivastava, Kavita Arora, Sapana Gupta, K.P. Murthy, R. D. Walter. (INF/PAT/05/2001)
7.
A process for
the preparation of novel 4-alkyl-7-O-(acetamid-2-yl)-2H-1-benzopyran-2-ones
useful as inhibitors of helminthic and protozoan DNA topoisomerases. Rama Pati Tripathi, Jitendra Kumar
Saxena, Onkar Prasad Shukla, Subhash Chandra, Puvada Kalpana Murthy, Shailija
Bhattacharya, Kamal Kamboj, Anil Kumar Dwivedi, Ranjeet Kumar Chatterjee,
Satyawan Singh, Vishwa Mohan Lal Srivastava, Anil Kumar Rastogi, Amiya Prasad
Bhaduri. (620/DEL/01)
8. N1, Nn-diglycosylated diamino alkanes useful as inhibitors of parasitic enzymes) Rama Pati Tripathi, Vinod Kumar Tiwari, Arvind Kumar Srivastava, Kavita Arora, Sapana Gupta, P. K. Murthy, R. D. Walter. (INF/PAT/06/2001)
9. A process for the preparation of novel combinatorial library of N1 – glycosylated and N3 - substituted ureas and thioureas useful as antitubercular agents, Rama Pati Tripathi, Vinod Kumar Tiwari, Ram Chandra Mishra, Ranjana Srivastava, Sudhir Sriwastava, Vinita Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava. (NF / 476 / 01)
10. Novel combinatorial library of N1 – glycosylated and N3 –substituted ures and thioureas Useful as antitubercular agents, Rama Pati Tripathi, Vinod Kumar Tiwari, Ram Chandra Mishra, Ranjana Srivastava, Sudhir Sriwastava, Vinita Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava. (NF / 474 / 01)
11. Diglycosylated diaminoalcohol as novel antitubercular agents, Rama Pati Tripathi, Vinod Kumar Tiwari, Neetu tewari, Ranjana Srivastava, Sudhir Srivastava, Vinita Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava. (NF/348/02)
12. A process for the preparation of diglycosylated diaminoalcohol as antitubercular agents Rama Pati Tripathi, Vinod Kumar Tiwari, Neetu tewari, Ranjana Srivastava, Sudhir Srivastava, Vinita Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava (NF/349/02)
13. Novel Galactopyranosylated aminoalcohols useful in chemotherapy of tubercular infections; Rama Pati Tripathi, Neetu Tewari, Ram Chandra Mishra, Ranjana Srivastava, Sudhir Sinha, Anil Srivastava, Vinita Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava (INF/PAT/09/02).
14. A process for the preparation of Galactopyranosylated aminoalcohols useful in chemotherapy of tubercular infections, Rama Pati Tripathi, Neetu tewari, Ram Chandra Mishra, Ranjana Srivastava, Sudhir Sinha, Anil Srivastava, Vinita Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava (INF/PAT/09/02)
15. Novel 1,3,5-thiazidine -2-thiones useful in chemotherapy of tubercular infections, Rama Pati Tripathi, Diksha Katiyar, Ranjana Srivastava, Anil Srivastava, Vinita Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava (NF/556/02)
16. A process for the preparation of 1,3,5-thiazidine -2-thiones useful in chemotherapy of tubercular infections, Rama Pati Tripathi, Diksha Katiyar, Ranjana Srivastava, Anil Srivastava, Vinita Chaturvedi, Kishor Kumar Srivastava, Brahm Shankar Srivastava, (NF/555/02)
17. A process for the synthesis of Novel Phenyl Cyclopropyl methanones useful as antitubercular agents, Rajesh Grover, R.C. Mishra, S.S. Verma, R.P. Tripathi, Raja Roy, A.K. Dwivedi, S.Singh, Ranjana Srivastava, Anil Srivastava, Vinita Chaturvedi, Manju Y. Krishnan , Brahm Shankar Srivastava 0375NF/2003
Chapters
in Book:
1. Synthesis and antifilarial evaluation of a few carbohydrate derivatives. R.P.Tripathi, V.Singh, A.R.Khan, A.P.Bhaduri, S.Bhatnagar and A.K. Srivastava. “Trends in Carbohydrate Chemistry,” edited by P.L.Soni, Surya International Publication, Dehradune pp 1-4 (1995).
2. Search of new drugs for tuberculosis: Glycosylated b-amino acids as new class of antitubercular agents, Trends in Carbohydrate Chemistry, Vol-8 (in press), and Published by Surya international publication, Dehradun. Authers: V.K.Tiwari, R. P. Tripathi, R. Tripathi, Laxmi Bala, S. Sinha, A. Srivastava, R. Srivastava, B.S. Srivastava.
Paper Presented in conference: (Last
three years)
1. Identification of inhibitors of DNA Topoisomerase II from a synthetic library of glycopeptides, R. P. Tripathi, S. K. Rastogi, B. Kundu, J.K. Saxena, S. Srivastava, V.J.M. Reddy, S. Chandra, A. P. Bhaduri, Fifth IUPAC International Symposium on Bio-Organic Chemistry, ISBOC-5, at National Chemical Laboratory- Pune, 3rd Jan - 4 th Feb 2001.
2. Unexpected Isomerisation reaction with DBU: An easy access to a-alkylidene tetrahydrofuranose, V. K. Tiwari and R. P. Tripathi, Current Trends in Drug Discovery Research, 11-15 Feb 2001 at CDRI Lucknow.
3. Antifilarial profile of a novel lead compound: 7-O- (4-methyl piperazin-acetyl)-4-methyl 2H-1- benzopyran-2-ones, R.P. Tripathi, V.K. Tiwari, S. Bhattacharya, K. Srivastava, V.M.L. Srivastava and K. Murty, Indian Conference of Parasitology, 1-3 Oct 2001 at Jodhpur.
4.
Synthesis of glycosylated amino esters as DNA
topoisomerase-II inhibitors A.R.Khan, R. P. Tripathi, V.K.Tiwari, R. C. Mishra, V. J. M.Reddy and J. K. Saxena, National Biorganic
Symposium 7, GNDU Amritsar 7-9 Nov 2001
5.
Depletion of intracellular Glutathione of Setaria cervi by
Dimethylmaleate, Phorone and Aminoalkane derivatives Sapana Gupta,V.K.Tiwari, R. P. Tripathi, A.
K. Sriwastava, Indian Conference of Parasitology, 1-3 Oct 2001 at Jodhpur.
6.
Glycosylated b-amino acids as new class of antitubercular agents V.K.Tiwari, R. P. Tripathi, R. Tripathi, Laxmi Bala, S.
Sinha, A. Srivastava, R. Srivastava, B. S. Srivastava, 16th
Carbohydrate Conference,6-7 December at Trivendrum.
7. Conjugate
Addition of Hydrazine and Hydroxyl Amines to Sugar derived Olefinic Esters:
Synthesis of glycosylated heterocycles R. C. Mishra, N. Tewari, R. P.
Tripathi, 22-24 Feb Alembic Ltd Vadodara.
8. Synthesis and bioevaluation of glycosyl ureas as a-glucosidase inhibitors and antituberculosis agents: V. K. Tiwari, Neetu Tewari, R.C. Mishra, R. P. Tripathi, A .K. Srivastava, R. Ahmad, R. Srivastava and B. S. Srivastava. International symposium on Drug Discovery and Process Research, Shivaji University Kolhapur, January 23-25, 2003.
9. A versatile synthesis of dihydropyrimidinone C-Nucleosides, R. C. Mishra, Diksha Katiyar, Neetu Tewari, R.P. Tripathi, International symposium on Drug Discovery and Process Research, Shivaji University Kolhapur, January 23-25, 2003.
10. a-glucosidase inhibitory potential of glycosyl ureas, Neetu Tewari, R.C. Mishra, R. Ahmad, A.K.Srivastava, and R.P. Tripathi, International conference on Role of Free Radical and antioxidants in Health and disease, King George Medical University Lucknow, February 10-12, 2003.
11. Glutathione modulatory potential of 4-alkyl-7-O-acetamidyl coumarins in malarial and filarial parasites, D. Katiyar, K. Arora, R. Ahmad, A. K. Srivastava, and R. P. Tripathi, International conference on Role of Free Radical and antioxidants in Health and disease, King George Medical University Lucknow, February 10-12, 2003.
Besides above more than 20 papers have also been presented in different national and international seminars and conferences
Invited Lectures:
1. Polysaccharides structure & function- its relevance to medicinal chemists-In Workshop at CSIR Science centre New Delhi 9th July 1991.
2. Carbohydrtes in Drug Design- In modern Trends in chemical research: From laboratory to Industry, March 5-7 1992, APS University Reewa, M.P.
3. Strategies in the design of antiviral agents: National Seminar organized by Purvanchal academy of Sciences March 1993, at Neoria Jaunpur.
4. Chemotherapy of filariasis-National Seminar organized by Purvanchal Academy of Sciences March 1993, at Purvanchal University Jaunpur 1994.
5. Development of drugs against Tuberculosis- Annual Convention Of Chemical Society of DBS college, Kanpur University, Kanpur December 2002
6. Carbohydrates in Drug Design: National Conference on Chemistry at Interfaces-Trends and Perspectives, December 19-20, 2003, Sant Longowal Institute of Technology, Longowal, Punjab
Besides above about 15 more research papers have been presented in national & international conferences.