Section 4: Types and Parts of Cells

      I.        Cells are the Simplest Unit of Life

    II.        The Plasma Membrane

   III.        The Cytoskeleton

  IV.        Prokaryotic Cells

   V.        Specialized Compartments of Eukaryotic Cells

 

I. Cells are the basic units of life

v  Every living organism consists of one to many billions of membrane-enclosed units called cells. 

o   Cells compose every organ of our bodies and determine how we look, move, and function as organisms.

o   In multicellular organisms, most cell types are specialists at something.

o   Much of what we know about cells came with the advent of the light microscope.

II. The plasma membrane is an outer boundary that separates the cell from its outside environment. 

v  Membranes are composed of phospholipids arranged in a bilayer with proteins embedded inside that allow the selective passage of materials in and out of the cell. 

o   Membranes are selectively permeable. 

v  According to the fluid-mosaic model, the proteins are free to move about sideways in the phospholipid bilayer. 

o   The type of proteins found in the cell’s membrane determines how the cell will function.

III. The cytoskeleton provides shape and movement for the cell.

v  The cytoskeleton acts as the internal support system for the cell, giving it structure.

v  The cytoskeleton also includes “cables” that act as tracks along which cell particles can move. 

v  The cytoskeleton is always changing, allowing some cells to change shape and move around on their own. 

v  Three main protein filaments compose the cytoskeleton: microtubules, intermediate filaments, microfilaments.

 

 

o   Microtubules: thickest of filaments

§  Made up of many monomers of tubulin

§  Can grow and shrink in length by adding/losing tubulin monomers at either end

§  Give cells their shape and support inner components

§  Act as “railroad tracks” for movement of materials through cell

o   Intermediate filaments: thinner than microtubules, thicker than microfilaments

§  Serve as structural reinforcements and hold organelles in place

§  Ex: skin cells; cell nucleus

o   Microfilaments: smallest in diameter

§  Most important of cell filaments for cell movement

§  Made up of monomers of actin (can change length rapidly)

§  Ex: fibroblasts

v  Cilia and flagella are part of the cytoskeleton

o   Both function due to the movement of the protein dynein “walking” up microtubule pairs, using energy derived from ATP

o   Cilia: hair-like projections

§  Can be used to move around in environment or to move objects nearby

§  Move like oars of a rowboat

o   Flagella: whip-like projections

§  Beat in a wave-like pattern in eukaryotic cells

IV. Prokaryotic cells

v  Prokaryotic cells lack internal compartments enclosed by membranes, and thus have little internal organization.

v  Most are spherical/rod-shaped, though circular, round, and corkscrew shapes exist. 

v  Most have a tough cell wall that forms outside the plasma membrane.

v  Most are much smaller than eukaryotic cells.

v  Inside the prokaryotic cell:

o   Cytosol

o   Nucleoid Region

o   Ribosomes

v  Prokaryotic flagella: most widespread method that bacteria use to propel themselves through their environment

o   Rotary “motor” rotates the flagellum like a propeller

o   The flagellum rotates in response to hydrogen ions that diffuse into the bacterium from the environment.

V. Eukaryotic cells have specialized membrane-bound compartments called organelles.

v  Inside the cell:

o   Cytoplasm: cytosol + organelles

§  Internal space inside organelles is the lumen.

v  Nucleus: double membrane

o   Directs activities of cell in response to signals received from other parts of the cell

o   Contains DNA

o   Surrounded by a nuclear envelope equipped with nuclear pores

v  Endoplasmic Reticulum: single membrane connected to outer membrane of nuclear envelope

o   Where cell’s chemical building blocks are manufactured

o   Extensive, complex network of interconnected tubes and flattened sacs stacked and connected to one another  

§  Sacs contain lipids and proteins that are destined for other cellular compartments.

o   ER can appear smooth or rough

§  Most ER is “Rough ER” that has ribosomes attached.  These ribosomes produce proteins that can go into the ER’s lumen, insert into a membrane, or be exported out of the cell.

§  Smooth ER marks sites where portions of the ER membrane actively bud off to produce vesicles. 

·         This is an effective means of transporting proteins that are embedded in ER or lipids and proteins that float free in ER lumen.

 

 

 

v  Golgi Apparatus: single membrane

o   Directs where proteins and lipids produced by ER should go

o   Chemical groups are also added to outbound molecules to direct them to other destinations in the cell.

§  Ex: carbohydrate molecules and phosphate groups

o   Appears like a series of flattened membranes stacked together and surrounded by small vesicles when viewed in the electron microscope

§  Vesicles transport proteins from ER to Golgi apparatus and between various sacs of the Golgi.

v  Lysosomes: single membrane

o   Contain enzymes used to break down macromolecules delivered to them in vesicles

§  Acidic pH in lumen (5)

o   Broken down products are transported into cytosol for use by the cell.

v  Vacuoles: single membrane

o   Related to lysosomes, but found in plants and fungi

o   Central vacuole: occupies 1/3 of plant cell’s total volume

§  Breaks down substances, and some can also store nutrients

§  Filled vacuoles often contribute to rigidity of plant

v  Mitochondria: double membrane

o   Breakdown sugar to synthesize energy-rich ATP to power the cell

o   Inner mitochondrial membrane has distinct folds called cristae.

§  Space between 2 membranes is intermembrane space.

§  Lumen inside the cristae is the mitochondrial matrix.

v  Chloroplasts: double membrane

o   Capture energy from sunlight and convert it to chemical energy

o   Contain additional organelles inside called chloroplasts (where photosynthesis takes place)

o   Beneath the double membrane lies a third, separate internal system of membranes arranged like stacked pancakes (stack=granum; each pancake=thylakoid).

 

 

PROKARYOTIC CELL: http://faculty.ircc.edu/faculty/tfischer/images/prokaryote%20overview.jpg

PLANT CELL:  http://waynesword.palomar.edu/images/plant3.gif                                                                          

 

 

 

ANIMAL CELL: http://waynesword.palomar.edu/lmexer1a.htm#animal

 

                                  

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