TrustWare's BufferZone
BufferZone prevents the intrusion of hostile code and eliminates signature/definition updating. All possible threats are neutralized in the virtual BufferZone in which unfamiliar programs can run without damage to systems; there is no possibility of data theft or replication by email, even by malware not yet recognized by conventional antivirus or antispyware software.
SpywareBlaster
SpywareBlaster alters your hosts list to prevent your computer from connecting to known websites that contain malware. SpywareBlaster does not update itself automatically and will not inform you when your definitions are out of date.