Effects of steroids
The East Germans believed that not only was it vital to avoid such pre-contest stressors, but they also believed they had to find ways to increase one's psychophysiological capacity so as to increase the ability to handle these pre-contest stressors (not to mention to handle the stress at contest time itself). effects of steroids Bodybuilding supplements. Now keep in mind that the matter of this research is not just applicable to athletes, but also to any one with decreased psychophysiological capacity (i. e. elderly), or who have to handle large amounts of stress (i. effects of steroids Steroid board. e. college exam studiers). The East German's discovered that appropriate administration of androgenic hormones had a marked effect on the psychophysiological capacity. effects of steroids Medicine and anabolic steroids. Substances that they are known to have studied and used for this purpose include mestanolone (methyl DHT), Oral-Turinabol (dehydrochloromethyltestosterone), testosterone, and androstenedione. Of particular significance are the compounds mestanolone and androstenedione. These two substances are known to have minimal anabolic properties on muscle mass, yet their ability to activate the stress handling capabilities of the CNS are equal to or greater than that of testosterone or other androgenic / anabolic steroids. One example in the literature describes the oral administration daily of 10mg mestanolone to 54 individuals who had been undergoing long term stress. An alpha wave increase of up to 4 Hertz was observed, and this was associated with a great increase in performance on tasks requiring high physical output, mental concentration and physical coordination. Although effective, oral administration of androgens was not the preferred technique of the East Germans. Instead they preferred the intra-nasal route. Due to the proximity of the nasal passages to the base of the brain, the East Germans believed that absorption here maximized the passage of steroids through the blood brain barrier and into the cerebrospinal fluid where they are available to stimulate genomic and non-genomic CNS androgenic activity. The intranasal route was also fast acting, which made it ideal for pre-contest usage. According to the East German data, after intra-nasal administration, levels of steroids in the blood maximize at 15 minutes and decline to baseline by 90 minutes. Levels in the CNS are probably elevated even sooner (seconds to minutes). Furthermore, with the usage of intranasal testosterone and androstenedione, the East Germans discovered that the ratio of urinary testosterone / epitestosterone were normalized within 24 hours, allowing them to pass post competition drug testing. PROHORMONES FOR CNS ACTIVATIONSo what significance does all this have to the average reader here? It has quite a bit of relevance because legal, over the counter, androgenic prohormones are actually "custom made" for harnessing the CNS powers of androgens. As was previously mentioned with the enzymes 5 alpha-reductase and aromatase, the enzymes that convert prohormones to active androgens (17 beta hydroxysteroid dehydrogenase and 3alpha(beta) dehydrogenase) are also heavily localized in the many of the same CNS centers. Therefore, administration of these prohormones, while not always substantially raising systemic (blood) levels of active androgens, can cause large increases in androgen activity in the key CNS centers. As a result, these prohormones can be considered "CNS targeted" versions of testosterone.
Effects of steroids
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