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		Gene (123 items)
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	Respiratory/Thoracic Cancers Other than Lung

	Lung Cancer
Lung Cancer >...>
	Specific Types of Lung Cancer
Lung Cancer >...>
	Small Cell Lung Cancer
Lung Cancer >...>
	Non-small Cell Lung Cancer
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ORIGINAL CONTRIBUTIONS:
Yang Mao, Saiyi Pan, Shi Wu Wen, and Kenneth C. Johnson
Physical Activity and the Risk of Lung Cancer in Canada

Am. J. Epidemiol., Sep 2003; 158: 564 - 575.


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... A population-based case-control study of 2,128 cases with histologically confirmed incident lung cancer and 3,106 population controls aged 20–76 years was conducted to assess the impact of ...

... recreational physical activity on lung cancer risk in Canada in 1994–1997. ...


	Confidence Intervals		Body Mass Index
	Case-Control Studies		Exercise
	Tobacco and Smoking		Epidemiology
	Lungs		Epidemiology, Causes, and Risks of Lung Cancer
	Environmental/Lifestyle Causes of Lung Cancer		Tobacco Use
	Incidence and Mortality of Lung Cancer		Lung Cancer

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MECHANISMS OF SIGNAL TRANSDUCTION:
Yi-He Ling, Leonard Liebes, Yiyu Zou, and Roman Perez-Soler
Reactive Oxygen Species Generation and Mitochondrial Dysfunction in the Apoptotic Response to Bortezomib, a Novel Proteasome Inhibitor, in Human H460 Non-small Cell Lung Cancer Cells

J. Biol. Chem., Sep 2003; 278: 33714 - 33723.


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... With human H460 lung cancer cells, bortezomib exposure at 0.1 {mu} m showed induction of apoptotic cell death starting ...

... targeting of its pathway has recently emerged as a promising approach for the development of anti-cancer agents. ...


	Mitochondrial Electron Transport Chain		Mitochondrial Apoptosis
	Mitochondrial Membrane		Mitochondrial Dysfunction
	Proteasome Inhibition		Mitochondrial Electron Transport
	Cytochrome C		Mitochondrial Translocation
	P53		C-Type Cytochrome
	Cyclosporine		Electron Transport Chain
	Antimycin A		Membrane Potential
	Mitochondrial Permeability		Cytochromes involved in Oxidative Phosphorylation

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FJ EXPRESS:
Brian Gardner, Li X. Zhu, Sherven Sharma, Donald P. Tashkin, and Steven M. Dubinett
Methanandamide increases COX-2 expression and tumor growth in murine lung cancer

FASEB J, Sep 2003; 10.1096/fj.03-0254fje.


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... Increased COX-2 expression and elevated PGE 2 have been associated with a poor prognosis in lung cancer. ...

... the impact of methanandamide on COX-2 expression, PGE 2 production, and tumor growth in murine lung cancer. ...

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Tamar Paz-Elizur, Meir Krupsky, Sara Blumenstein, Dalia Elinger, Edna Schechtman, and Zvi Livneh
DNA Repair Activity for Oxidative Damage and Risk of Lung Cancer

J Natl Cancer Inst, Sep 2003; 95: 1312 - 1319.


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... Background: Although smoking is a major cause of lung cancer, only a proportion of smokers develop lung cancer, suggesting a genetic predisposition in some ...

... 8-oxoguanine DNA N -glycosylase (OGG), which repairs the oxidative DNA lesion 8-oxoguanine, is associated with lung cancer. ...


	Genetic Predisposition to Disease		Hereditary Causes of Lung Cancer
	Genetics		Lungs
	Tobacco Use Cessation		Tobacco and Smoking
	Smoking Cessation		DNA Damage Response
	Epidemiology		Genetic Testing
	Prevention of Lung Cancer		Confidence Intervals
	Incidence and Mortality of Lung Cancer		Oxidative Damage
	Environmental/Lifestyle Causes of Lung Cancer		Genetic Causes of Cancer

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MEDICAL SCIENCES:
Tatsuo Ohira, Robert M. Gemmill, Kevin Ferguson, Sophie Kusy, Joëlle Roche, Elisabeth Brambilla, Chan Zeng, Anna Baron, Lynne Bemis, Paul Erickson, Elizabeth Wilder, Anil Rustgi, Jan Kitajewski, Edward Gabrielson, Roy Bremnes, Wilbur Franklin, and Harry A. Drabkin
WNT7a induces E-cadherin in lung cancer cells

PNAS, Sep 2003; 100: 10429 - 10434.


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... E-cadherin loss in cancer is associated with de-differentiation, invasion, and metastasis. ...

... We previously reported that expression of WNT7a, encoded on 3p25, was frequently downregulated in lung cancer, and that loss of E-cadherin or {beta}-catenin was a poor prognostic feature. ...


	Glycogen Synthase Kinase-3 Family		Catenins
	Catenin Signal Transduction		Fruit Fly
	RNA Interference		Lungs
	Catenin Signaling		Biology of Lung Cancer
	Glycogen Synthase Kinase-3		Metastasis
	Histone		Lung Cancer

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MOLECULAR EPIDEMIOLOGY AND CANCER PREVENTION:
Shi Qiuling, Zheng Yuxin, Zheng Suhua, Xiao Cheng, Leng Shuguang, and He Fengsheng
Cyclin D1 gene polymorphism and susceptibility to lung cancer in a Chinese population

Carcinogenesis, Sep 2003; 24: 1499 - 1503.


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... objective was to study the relationship between cyclin D1 gene ( CCND1 ) polymorphism and lung cancer in the Chinese population. ...

... genotype was associated with a significantly increased risk (OR = 1.87, 95% CI 1.01–3.45) for lung cancer. ...


	Polymorphism		Lungs
	Epidemiology		Tobacco and Smoking
	Genotype		Case-Control Studies
	Genetics		Cyclin D1
	Squamous Cell Lung Cancer		Cell Cycle Regulators
	Incidence and Mortality of Lung Cancer		Cyclin D
	Environmental/Lifestyle Causes of Lung Cancer		Genetic Polymorphism
	Hereditary Causes of Lung Cancer		Exons

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REVIEW SERIES:
C Parker and E Neville
Lung cancer • 8: Management of malignant mesothelioma

Thorax, Sep 2003; 58: 809 - 813.


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... The presence of asbestos fibres in the lungs of the general population suggests that exposure may occur unknowingly and there appears to be ...

... a substantial variation in fibre accumulation within areas of the lung. ...


	Brachial Plexi		Treatment Options for Lung Cancer
	Palliative Care		Incidence and Mortality of Lung Cancer
	Emotions		Environmental/Lifestyle Causes of Lung Cancer
	Environment and Public Health		Pleura
	Chest Pain		Lungs
	Asbestos Exposure		Nerves
	Dyspnea		Malignant Mesothelioma
	Policy and Patient Care Issues for Lung Cancer		Incidence

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REVIEWS:
M Siegel and M Skeer
Exposure to secondhand smoke and excess lung cancer mortality risk among workers in the "5 B’s": bars, bowling alleys, billiard halls, betting establishments, and bingo parlours

Tob. Control, Sep 2003; 12: 333 - 338.


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... "5 B's") as assessed by ambient nicotine air concentration measurements and to estimate the excess lung cancer mortality risk associated with this exposure. ...

... We then estimated the working lifetime excess lung cancer mortality risk associated with this exposure, as well as with exposure at the upper ...


	Incidence and Mortality of Lung Cancer		Medline
	Environmental/Lifestyle Causes of Lung Cancer		Epidemiology, Causes, and Risks of Lung Cancer
	Tobacco and Smoking		Epidemiology
	Mortality and Morbidity		Lung Cancer
	Lungs

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LUNG CANCER:
R L Manser, L B Irving, G Byrnes, M J Abramson, C A Stone, and D A Campbell
Screening for lung cancer: a systematic review and meta-analysis of controlled trials

Thorax, Sep 2003; 58: 784 - 789.


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	Lungs		Epidemiology
	Incidence and Mortality of Lung Cancer		Clinical Trials
	Detection/Screening and Prognosis of Lung Cancer		Radiography
	Helical CT		Tomography
	CT Scans		Lung Cancer
	Mortality and Morbidity		Public Health
	Screening		Diagnostic Imaging Techniques
	Surviving Cancer		Early Detection/Screening

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REGULAR ARTICLES:
Akira Masuda, Ken Maeno, Taku Nakagawa, Hiroko Saito, and Takashi Takahashi
Association between Mitotic Spindle Checkpoint Impairment and Susceptibility to the Induction of Apoptosis by Anti-Microtubule Agents in Human Lung Cancers

Am. J. Pathol., Sep 2003; 163: 1109 - 1116.


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... Anti-microtubule agents such as vinorelbine and paclitaxel, which are extensively used in the treatment of lung cancers, activate mitotic spindle checkpoint. ...

... role in the genesis of chromosome instability, we previously reported its frequent impairment in human lung cancer cell lines. ...


	Chromosomal Instability		Paclitaxel / Taxol
	Spindle Assembly		Vinorelbine
	Mitotic Inhibition		Humans
	Apoptotic Inducers		Spindle Activities
	Spindles		Mitotic Spindle Apparatus
	Lungs		Apoptosis
	Treatment Options for Lung Cancer

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