Name:                                                                                .                 2003 11 27

 

Read questions carefully. Attempt all questions as no marks will be deducted for incorrect responses.

The value of each question is one mark unless otherwise specified.     TOTAL   10K

 

1.  Which of the following is NOT an absolute requirement for DNA replication to take place?

 

A. single-stranded DNA          B.DNA polymerase

C. RNA primer                        D. Ribosomes

 

2. Semi-conservative DNA replication means:

            A.   The parent DNA molecule is completely broken down

            B.   The parent DNA remains completely intact

            C.   Each new DNA molecule contains one parental strand

            D.   Only half of the DNA is replicated

 

3. The two polynucleotide strands in a DNA molecule are like the east-west lanes of       the 401 highway because they show

 

A. cloverleaf structures                                  C. a helical structure

B. they are constantly under repair              D. anti-parallel orientation

 

4. Which of the following statements regarding DNA replication is incorrect?

 

A. DNA polymerase can start only at the 3’  end of an existing nucleotide.

B. DNA polymerase requires an RNA primer.

C. DNA replication is always in the 5’ to 3’ direction.

D. DNA replication is always in the 3’ to 5’ direction.

5. The building blocks of nucleic acid molecules are called _____.

A. polysaccharides            B.   amino acids          C.    fatty acids

D.  nucleotides                  E.DNA and RNA

 

6. DNA contains adenine (A), cytosine (C), guanine (G), and thymine (T). Chargaff formulated the following rule about the amounts of the bases        

            A.  A = T and C = G                 C.  A = C and T = G    

            B. C = T and A = G                  D.  A = U and C=G

7. A DNA nucleotide may contain

A.         deoxyribose, cytosine, lipid

B.         deoxyribose, thymine, phosphate

C.         deoxyribose, uracil, phosphate

D.         deoxyribose, thymine, phosphorus

8. What is the primer that is required to initiate the synthesis of a new DNA strand?

 

A. DNA nucleotides                 C. RNA nucleotides

B. protein                                D. DNA polymerase

9. Which enzyme – function is mismatched?

A. DNA polymerase – DNA replication

B. RNA polymerase – RNA transcription

C. helicase – keeps the strands open

D. primase – lays down primer

 

10. The flow of information in a cell proceeds _____.

A.  from RNA to DNA to protein

B.   from protein to RNA to DNA

C.   from DNA to protein to RNA

D.   from RNA to protein to DNA

E.   from DNA to RNA to protein (central dogma of genetics)

 

BONUS (1) What the %&$* is an Okazaki fragment?

 

Segment of newly replicated DNA produced during discontinuous DNA replication

 (OR stretches of DNA between RNA primers on the lagging strand

OR something to that effect)