N.J. Knowles - Refereed publications

- Harris, T.J.R., Underwood, B.O., Knowles, N.J., Crowther, J.R. and Brown, F.
(1979). Molecular approach to the epidemiology of swine vesicular disease: correlation of
variation in the virus structural polypeptides with serological properties. Infection
and Immunity 24: 593-599.
- Knowles, N.J., Buckley, L.S. and Pereira, H.G. (1979). Classification of porcine
enteroviruses by antigenic analysis and cytopathic effects in tissue culture: description
of 3 new serotypes. Archives of Virology 62: 201-208.
- Knowles, N.J. and Buckley, L.S. (1980). Differentiation of porcine enterovirus
serotypes by complement fixation. Research in Veterinary Science 29: 113-115.
- Knowles, N.J. (1983). Isolation and identification of porcine enteroviruses in
Great Britain, 1979 to 1980. British Veterinary Journal 139: 19-22.
- Donaldson, A.I., Ferris, N.P., Knowles, N.J. and Barnett, I.T.R. (1983).
Comparative studies of United Kingdom isolates of swine vesicular disease virus. Research
in Veterinary Science 35: 295-300.
- Espinoza, A.M. and Knowles, N.J. (1983). A serological and biochemical study of
new field isolates of foot-and-mouth disease virus type A in Peru, 1975 to 1981. Veterinary
Microbiology 8: 555-562.
- Knowles, N.J. and Barnett, I.T.R. (1985). A serological classification of bovine
enteroviruses. Archives of Virology 83: 141-155.
- Hamblin, C., Knowles, N.J. and Hedger, R.S. (1985). Isolation and identification
of bovid enteroviruses from free-living wild animals in Botswana. Veterinary Record
116: 238-239.
- Knowles, N.J. and Hedger, R.S. (1985). A study of antigenic variants of
foot-and-mouth disease virus by polyacrylamide gel electrophoresis of their structural
polypeptides. Veterinary Microbiology 10: 347-357.
- Caracappa, S., Vesco, G., Iannizzotto, G., Guercio, V. and Knowles, N.J. (1985).
Isolation and identification of porcine enteroviruses in Sicily. (Isolamento ed
identificazione di enterovirus suini in Sicilia). Archivio Veterinario Italiano
36: 167-170.
- Sharma, A.K., Knowles, N.J., Prasad, S. and Shrivastava, R.N. (1986). Preliminary
studies on a sheep enteroviruses. Indian Journal of Virology 2: 86-88.
- Shin, T.K., Lee, C.S., Kwon, H.J. and Knowles, N.J. (1987). Serological
classification of porcine enteroviruses isolated in Korea. Korean Journal of
Veterinary Research 27: 223-226.
- Gershon, P.D. and Knowles, N.J. (1988). FRAGMAP - a program for restriction site
map comparison. Nucleic Acids Research 16: 1779-1787.
- Knowles, N.J. (1988). The association of group III porcine enteroviruses with
epithelial tissue. Veterinary Record 122: 441-442.
- Samuel, A.R. and Knowles, N.J. (1988). Serological and biochemical study of an
isolate of foot-and-mouth disease virus type A from Bavaria in 1984. Revue
scientifique et technique de l'Office International des Epizooties 7: 365-373.
- Samuel, A.R., Knowles, N.J. and Kitching, R.P. (1988). Serological and
biochemical analysis of some recent type A foot-and-mouth disease virus isolates from the
Middle East. Epidemiology and Infection 101: 577-590.
- Craig, J.C., Parkinson, D. and Knowles, N. (1989). The suitability of different
microtitre plates for detection of antibody to virus antigens by indirect ELISA. Journal
of Biological Standardization 17: 125-135.
- Kitching, R.P., Knowles, N.J., Samuel, A.R. and Donaldson, A.I. (1989).
Development of foot-and-mouth disease virus strain characterisation - a review. Tropical
Animal Health and Production 21: 153-166.
- Craig, J.C., Parkinson, D., Goatley, L. and Knowles, N. (1989). Assay sensitivity
and differentiation of monoclonal antibody specificity in ELISA with different coating
buffers. Journal of Biological Standardization 17: 281-289.
- Knowles, N.J. and Sharma, G.K. (1990). A study of antigenic variants of
foot-and-mouth disease virus type A in India between 1977 and 1985. Revue scientifique
et technique de l'Office International des Epizooties 9: 1157-1168.
- Ryan, M.D., Jenkins, O., Hughes, P.J., Brown, A., Knowles, N.J., Booth, D.,
Minor, P.D. and Almond, J.W. (1990). The complete nucleotide sequence of enterovirus type
70: relationships with other members of the Picornaviridae. Journal of
General Virology 71: 2291-2299.
- Samuel, A.R., Ouldridge, E.J., Arrowsmith, A.E.M., Kitching, R.P. and Knowles, N.J.
(1990). Antigenic analysis of serotype O foot-and-mouth disease virus isolates from the
Middle East, 1981 to 1988. Vaccine 8: 390-396.
- Seechurn, P., Knowles, N.J. and McCauley, J.W. (1990). The complete nucleotide
sequence of a pathogenic swine vesicular disease virus. Virus Research 16:
255-274.
- Mart�nez, M.A., Hern�ndez, J., Piccone, M.E., Palma, E.L., Domingo, E., Knowles,
N.J. and Mateu, M.G. (1991). Two mechanisms of antigenic diversification of
foot-and-mouth disease virus. Virology 184: 695-706.
- McCauley, J. and Knowles, N. (Eds) (1991). Viral sequence data: a listing of
viral and phage sequence references and accession numbers, complete up to February 1991. Virus
Research 19: 241-499.
- Samuel, A.R., Knowles, N.J., Samuel, G.D. and Crowther, J.R. (1991). Evaluation
of a trapping ELISA for the differentiation of foot-and-mouth disease virus strains using
monoclonal antibodies. Biologicals 19: 299-310.
- Kitching, R.P., Samuel, A.R. and Knowles, N.J. (1992). The epidemiology of
foot-and-mouth disease based on nucleotide sequences of FMD virus. Animal
Biotechnology Bulletin 2: 5-7.
- Mart�nez, M.A., Dopazo, J., Hern�ndez, J., Mateu, M.G., Sobrino, F., Domingo, E. and Knowles,
N.J. (1992). Evolution of the capsid protein genes of foot-and-mouth disease virus.
Antigenic variation without accumulation of amino acid substitutions over six decades. Journal
of Virology 66: 3557-3565.
- Vosloo, W., Knowles, N.J. and Thomson, G.R. (1992). Genetic relationships between
southern African SAT-2 isolates of foot-and-mouth disease virus. Epidemiology and
Infection 109: 547-558.
- Zhang, G., Wilsden, G., Knowles, N.J. and McCauley J.W. (1993). Complete
nucleotide sequence of a coxsackie B5 virus and its relationship to swine vesicular
disease virus. Journal of General Virology 74: 845-853.
- Samuel, A.R., Ansell, D.M., Rendle, R.T., Armstrong, R.M., Davidson, F.L., Knowles,
N.J. and Kitching, R.P. (1993). Field and laboratory analysis of an outbreak of
foot-and-mouth disease in Bulgaria in 1991. Revue scientifique et technique de
l'Office International des Epizooties 12: 839-848.
- Chamberlain, R.W., Wamwayi, H.M., Hockley, E., Shaila, M.S., Goatley, L., Knowles,
N.J. and Barrett, T. (1993). Evidence for different lineages of rinderpest virus
reflecting their geographic isolation. Journal of General Virology 74: 2775-2780.
- Ansell, D.M., Samuel, A.R., Carpenter, W.C. and Knowles, N.J. (1994). Genetic
relationships between foot-and-mouth disease type Asia 1 viruses. Epidemiology and
Infection 112: 213-224.
- Woodbury, E.L., Samuel, A.R., Knowles, N.J., Hafez, S.M. and Kitching, R.P.
(1994). Analysis of mixed foot-and-mouth disease virus infections in Saudi Arabia:
prolonged circulation of an exotic serotype. Epidemiology and Infection 112:
201-211.
- Dawe, P.S., Sorensen, K.J., Ferris, N.P., Barnett, I.T.R., Armstrong, R.M. and Knowles,
N.J. (1994). Experimental transmission of foot-and-mouth disease virus from carrier
African buffalo (Syncerus caffer) to cattle in Zimbabwe. Veterinary Record
134: 211-215.
- Dawe, P.S., Flanagan, F.O, Madekurozwa, R.L., Sorensen, K.J., Anderson, E.C., Foggin,
C.M., Ferris, N.P. and Knowles, N.J. (1994). Natural transmission of foot-and-mouth
disease virus from African buffalo (Syncerus caffer) to cattle in a wildlife area
of Zimbabwe. Veterinary Record 134: 230-232.
- Armstrong, R.M., Samuel, A.R., Carpenter, W.C., Rama Kant and Knowles, N.J.
(1994). A comparative study of serological and biochemical methods for strain
differentiation of foot-and-mouth disease type A viruses. Veterinary Microbiology
39: 285-298.
- Woodbury, E.L., Samuel, A.R. and Knowles, N.J. (1995). Serial passage in tissue
culture of mixed foot-and-mouth disease virus serotypes. Archives of Virology
140: 783-787.
- Minor, P.D., Brown, F., Domingo, E., Hoey, E., King, A., Knowles, N., Lemon, S.,
Palmenberg, A., Rueckert, R., Stanway, G. Wimmer, E. and Yin-Murphy, M. (1995). Picornaviridae.
In: Virus Taxonomy. Classification and Nomenclature of Viruses. Sixth Report of the
International Committee on Taxonomy of Viruses. Murphy, F.A., Fauquet, C.M., Bishop,
D.H.L., Ghabrial, S.A. and Jarvis, A.W. Vienna: Springer-Verlag Archives of Virology
(Suppt. 10) 329-336.
- Davidson, F.L, Crowther, J.R., Nqindi, J., Knowles, N.J., Thevasagayam, S.J. and
Van Vuuren, C.J. (1995). Antigenic analysis of SAT 2 serotype foot-and-mouth disease virus
isolates from Zimbabwe using monoclonal antibodies. Epidemiology and Infection 115:
193-205.
- Sharma, A., Prasad, S., Shrivastava, R.N. and Knowles, N.J. (1996). Isolation and
characterization of enteroviruses from sheep. International Journal of Animal Sciences
11: 95-98.
- Hyypi�, T., Hovi, T., Knowles, N.J. and Stanway, G. (1997). Classification of
enteroviruses based on molecular and biological properties. Journal of General
Virology 78: 1-11.
- Brocchi, E., Zhang, G., Knowles, N.J., Wilsden, G., McCauley, J.W., Marquardt,
O., Ohlinger, V.F. and De Simone, F. (1997). Molecular epidemiology of recent outbreaks of
swine vesicular disease: two genetically and antigenically distinct variants in Europe,
1987-1994. Epidemiology and Infection 118: 51-61.
- Lin, F., Mackay, D.K.J. and Knowles, N.J. (1997). Detection of swine vesicular
disease virus RNA by reverse transcription-polymerase chain reaction. Journal of
Virological Methods 65: 111-121.
- Koenen, F., Vanderhallen, H., Papadopoulos, O., Billinis, C., Paschaleri-Papadopoulou,
E., Brocchi, E., De Simone, F., Carra, E. and Knowles, N.J. (1997). Comparison of
the pathogenic, antigenic and molecular characteristics of two encephalomyocarditis virus
(EMCV) isolates from Belgium and Greece. Research in Veterinary Science 62:
239-244.
- Samuel, A.R., Knowles, N.J., Kitching, R.P. and Hafez, S.M. (1997). Molecular
analysis of type O foot-and-mouth disease viruses isolated in Saudi Arabia between 1983
and 1995. Epidemiology and Infection 119: 381-389.
- Haydon, D.T., Lea, S., Fry, L., Knowles, N., Samuel, A.R., Stuart, D. and
Woolhouse, M.E.J. (1998). Characterizing sequence variation in the VP1 capsid proteins of
foot-and-mouth disease virus (serotype O) with respect to virion structure. Journal of
Molecular Evolution 46: 465-475.
- Haydon, D., Knowles, N. and McCauley, J. (1998). Methods for the detection of
non-random base substitution in virus genes: models of synonymous nucleotide substitution
in picornavirus genes. Virus Genes 16: 253-266.
- Lin, F., Mackay, D.K.J. and Knowles, N.J. (1998). The persistence of swine
vesicular disease virus infection in pigs. Epidemiology and Infection 121:
459-472.
- Martin, L.-A., Meyer, A.J., O'Hara, R.S., Fu, H., Mellor, P.S., Knowles, N.J. and
Mertens P.P.C. (1988). Phylogenetic analysis of African horse sickness virus segment 10:
sequence variation, virulence characteristics and cell exit. Archives of Virology
[Supplement] 14: 281-293.
- Pattnaik, B., Venkataramanan, R., Tosh, C., Sanyal, A., Hemadri, D., Samuel, A.R., Knowles,
N.J. and Kitching, R.P. (1998). Genetic heterogeneity of Indian field isolates of
foot-and-mouth disease virus serotype O as revealed by partial sequencing of 1D gene. Virus
Research 55: 115-127.
- Knowles, N.J., Dickinson, N.D., Wilsden, G., Carra, E., Brocchi, E. and De
Simone, F. (1998). Molecular analysis of encephalomyocarditis viruses isolated from pigs
and rodents in Italy. Virus Research 57: 53-62.
- Samuel, A.R., Knowles, N.J. and Mackay, D.K.J. (1999). Genetic analysis of type O
viruses responsible for epidemics of foot-and-mouth disease in North Africa. Epidemiology
and Infection, in press.
- Nijhar, S.K., Mackay, D.K.J., Brocchi, E., Ferris, N.P., Kitching, R.P. and Knowles,
N.J. (1999). Identification of neutralizing epitopes on a European strain of swine
vesicular disease virus. Journal of General Virology 80: 000-000, in press.
- Marvil, P., Knowles, N.J., Mockett, A.M.A., Britton, P., Brown, T.D.K. and
Cavanagh, D. (1999). Avian encephalomyelitis virus is a picornavirus and is most closely
related to hepatitis A virus. Journal of General Virology, in press.
- Koenen, F., Vanderhallen, H., Dickinson, N.D. and Knowles, N.J. (1999).
Phylogenetic analysis of European encephalomyocarditis viruses: comparison of two genomic
regions. Archives of Virology, in press.
- Zhang, G., Haydon, D.T., Knowles, N.J., McCauley, J.W. (1999). Molecular
evolution of swine vesicular disease virus. Journal of General Virology,in press.
- Peng, J.H., McCauley, J.W., Kitching, R.P. and Knowles, N.J. (1999). Nucleotide
sequence of porcine enterovirus type 9. Journal of General Virology, in press.

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