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19th-Century Medicine In the 19th century great advances occurred in diagnosis and treatment of disease and in surgical methods. European researchers established the sciences of embryology and histology and the central concept of the cell as the seat of disease. British scientist Charles Darwin advanced his theory of evolution. Austrian biologist Gregor Johann Mendel laid out the basis of classical genetics. Studies of fermentation by French chemist and microbiologist Louis Pasteur revived interest in the contagion theory of disease. Pasteur and German physician and bacteriologist Robert Koch founded the field of bacteriology, considered the greatest single advance in the history of medicine; many bacterial diseases became preventable or controllable. Bacteriology allowed important discoveries, including the role of white blood cells in destroying microbes, the way in which bacteria are carried, and the necessity of sterilization to prevent wound infection (see Antiseptics). Other advances during this time took place in physiology (including understanding of various glands and the nervous system), organic chemistry and metabolism, optics and ophthalmology, and psychology. The X ray was discovered by German physicist Wilhelm Conrad Roentgen; French physicists Pierre and Marie Curie discovered radium. American physicians developed the field of gynecology and identified mosquitoes as carriers of yellow fever. |
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20th-Century Medicine The most important medical finding of the 20th century was the discovery by American biologist James Dewey Watson and English physicist Francis Harry Compton Crick of the structure of the genetic material, deoxyribonucleic acid, or DNA (see Nucleic Acids). By 1970 the first gene had been synthesized; by the mid-1980s genetic techniques were being used medically, and genetic engineering was producing large quantities of pure human substances such as hormones and interferon. Surgery advanced with the development of operating microscopes and other techniques that allow delicate procedures such as reattachment of severed limbs. Medical milestones were reached with the successful transplantation of organs and the development of the artificial heart and kidney. Plastic replacements for joints relieved some patients from crippling arthritis, and lasers were developed for medical use, especially in eye surgery. Many infectious diseases have been conquered in the 20th century by improved sanitation, antibiotics, and vaccines. Especially important were the developments of the sulfonamide antibiotics and penicillin, which immediately saved many lives in World War II (1939-1945). Streptomycin, another drug, was used to defeat tuberculosis. Vaccines are widely used against viral diseases, including poliomyelitis, diphtheria, tetanus, yellow fever, measles, mumps, rubella (German measles), hepatitis B, influenza, herpes simplex, and chicken pox. Vaccine production was aided by new techniques such as tissue culture production and genetic engineering. In the latter part of the 20th century many microorganisms became resistant to antibiotics, and new diseases emerged, such as Legionnaires' disease and acquired immune deficiency syndrome (AIDS). In the 20th century the brain was carefully explored. Using chemical dyes and sophisticated imaging devices, scientists discovered the specific parts of the brain that control hearing, speech, and movement of the limbs; they showed that the right and left halves of the brain were functionally different. The discovery of the chemical/electrical method of nerve impulse transmission was an important finding, as were the complex way in which the brain regulates body function by hormones and the complex connection between emotions and biochemistry. Treatments became available for neurological diseases such as epilepsy and Parkinson's disease. Scientific insight into the workings of the immune system and the structure of antibody molecules has allowed better treatment of immune disorders, even temporary disabling of the immune system to prevent rejection of transplanted organs (see Transplantation, Medical). One form of antibody molecule proved to be associated with allergy, now viewed as an immune system disorder. The typing of blood by immune specificity has made transfusion safe and widely applicable (see Blood Type; Blood Transfusion). In recent years, new and better methods of seeing inside the human body have revolutionized medical diagnosis. The computerized axial tomography (CAT) scanner is a computer-assisted X-ray device (see X Ray; Radiology). Nuclear magnetic resonance imaging employs radio waves to identify molecular structure. Ultrasound produces images from sound waves, and positron emission tomography scans the body with antimatter. The treatment of mental illnesss first became scientific and successful in the 20th century. Austrian physician and neurologist Sigmund Freud pioneered the methods of psychoanalysis |
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