It is the heart of the Indus Valley Civilization dating back to 3rd millennium B.C. Thousands of tourists from all over the world are attracted every year to visit the ruins of Moenjodaro near Larkana. An elaborate canal system taken from Sukkur Barrage at Sukkur, Upper Sindh Barrage north of Sukkur at Guddu, and Lower Sindh Barrage (Ghulam Muhammad Barrage) at Hyderabad, irrigate together in this area over 10 million acres and account for about 40 per cent of Pakistan's irrigated land. The fertile area yields abundant crops of rice, wheat and cotton and contains the bulk of the population and most of the major commercial and industrial centres of Sindh such as Hyderabad, Sukkur, Larkana, Nawabshah , Shikarpur and Dadu.
However, its southern part is one of the worst areas of Pakistan for waterlogging and salinity. There are many lakes in Sindh, which attract thousands of migratory birds during the winter season from Central Asia. Manchhar lake with its highly pulsating expanse of about 200 sq.miles of area is the largest lake. With its foliage of towering grasses, its meadows of floating lotus, its inhabitants in their floating habitations, the lake presents an attractive look. Further south, stretches the Indus Delta, which is a savage waste.