| NANOCANCER |
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| UPDATED DECEMBER 10, 2005 |
| QDs/Cancer/Targeting Cancer Cells/Quantum dots simultaneously target and image cancer cells in live mice/ ACS.org URL |
| pSi/Porous Silicon/pSivida/Cancer/Isotopes/EP1,175,233 - DERIVATIZED POROUS SILICON=WO0066190 pSivida March 15 Press Release |
| Ralph Weissleder, Mukesh Harisinghani - Massachusetts General Hospital in Boston Breakthrough in 'nano' tracking of cancer hailed Link to article Link to RB message Link to medical journal PloS Medicine |
| University of Melbourne, Frank Caruso Exploding Microcapsules Target Tumors The bombs are tiny drug-enclosing polymer capsules covered with gold nanoparticles and attached to tumor-seeking antibodies. The plan is for the nanoparticles to collect inside tumors. Once there, a pulse from a near-infrared laser could be used to melt the gold�which strongly absorbs light at this wavelength �and rupture the capsules to release drugs within. Link to article |
| Alex Khromykh, University of Queensland Replikun Biotech company to commercialise the new technology, baptised KUNrep Australians say virus could point way to vaccine for HIV, cancer A virus found in northern Australian mosquitoes could provide the basis for vaccines to prevent AIDS and cure cancer, researchers said on Thursday. The research team based in Queensland state said proteins taken from the mosquito-borne Kunjin virus had the potential to provide either gene therapy treatment or preventive vaccines for a range of deadly diseases. Link |
| Nanomaterials Used in Possible Cancer Cure/Cal Tech/Children's Hospital LA "Medical researchers at CalTech and the Children's Hospital in Los Angeles have successfully inhibited cancer growth in mice by wrapping engineered RNA in nanomaterials and introducing them into the bloodstream. Two polymers and a special coating allow the therapeutic RNA to enter the cancer cell and release the therapeutic RNA payload. The new technique has slowed or prevented the development of secondary tumors in lab mice with Ewing's sarcoma. Further testing is planned on humans, and with other cancers. Link 1 Link 2 Link 3 Insert Therapeutics - ARROWHEAD RESEARCH CORPORATION - ARWR Describes In Vivo Performance and Versatility of Lead Anticancer Compound 04/20/05 -- Insert Therapeutics, Inc. Chief Scientific Officer, Thomas Schluep, Sc.D., presented data today demonstrating the improved biodistribution and preclinical efficacy in vivo of its lead anticancer compound, IT-101. Insert Therapeutics, a majority-owned subsidiary of Arrowhead Research Corporation (Nasdaq:ARWR), is progressing towards a broad-based Phase I clinical trial for IT-101, a combination of Insert's patented polymer technology, Cyclosert(TM), and the anti-cancer compound camptothecin. Subject to the filing by Insert of an Investigational New Drug application with the US Food and Drug Administration, and upon clearance of regulatory requirements, Phase I/II human safety and efficacy trials are scheduled to begin at The City of Hope (COH) Medical Center in late 2005. Link1 Link 2 Link 3 - The Fool |
| Stanford, Hongjie Dai Nanotube-Laser Combo Selectively Targets Cancer Cells, Study Shows CNTs when paired with a modified laser beam can act as tiny heaters to selectively destroy tumor cells. Link |
| UCLA, Chen, AIDS Virus, Destroy cancer cells US scientists hope to be able to use a harmless form of the Aids virus to seek and destroy cancer cells. A University of California team found an "impotent" version of HIV, with the disease-causing parts of it removed, tracked down cancer cells in mice. Link 1 Link 2 |
| UCSB, Safinya, Wilson, Smart Bio Nanotube The nanotubes are "smart" because they can open or close at the ends, depending on how the researchers manipulate the electric charge on the two components. So in principle, a nanotube could encapsulate a drug or a gene, and then open on command to deliver the cargo where it would have the best effect. Link to article Link to PNAS |
| MIT, Sasisekharan, Nano-Sized Bomb Targets Tumors Engineered as a bubble within a bubble, the molecule's outer shell is designed to look like a fat cell, helping it to evade the body's immune system, which might otherwise recognize it as a foreign object and attack it. Link |