24. Yi-Kun Chiang, Ching-Chuan Kuo, Chiung-Tong Chen, Mohane S. Coumar, Hsing-Pang Hsieh, Chi-Yen Chang, Huan-Yi Jseng, Ming-Hsine Wu, Jian-Sung Wu, Jiun-Shyang Leou, Jen-Shin Song, Jang-Yang Chang, Ping-Chiang Lyu, Yu-Sheng Chao and Su-Ying Wu. Generation of Ligand-Based Pharmacophore Model and Virtual Screening for Identification of Novel Tubulin Inhibitors with Potent Anticancer Activity - J Med Chem (Under major revision: Feb 2009).
23. Chia-Hui-Lin, Yi-Hui Peng, Mohane Selvaraj Coumar, Santhosh Kumar Chittimalla, Chin-Chieh Huang, Tzu-wen Lien, Wen-Hsin Lin, John T.-A. Hsu, Uan-Kang Tan, Jai-Hong Cheng, Xin Chen, Chun-Chen Liao, Ping-Chiang Lyn, Yu-Sheng Chao, Su-Ying Wu, and Hsing-Pang Hsieh. �Design and structural analysis of novel pharmacophores for potent and selective PPARg agonists� J Med Chem (Accepted: Feb 2009).
22. Chun Hei Antonio Cheung, Mohane Selvaraj Coumar, Jang-Yang Chang, Hsing-Pang Hsieh. �Aurora Kinase Inhibitors in Preclinical and Clinical Testing� Expert opinion on Investigational Drugs � Accepted (Feb 2009).
21. Mohane Selvaraj Coumar, Chun Hei Antonio Cheung, Jang-Yang Chang, Hsing-Pang Hsieh. �Advances in Aurora Kinase Inhibitors and their Patents� Expert opinion on Therapeutic Patents � Accepted (Nov 2008).
20. Mohane Selvaraj Coumar, Jiun-Shyang Leou, Paritosh Shukla, Jian-Sung Wu, Ajay Kumar Dixit, Wen-Hsing Lin, Chun-Yu Chang, Tzu-Wen Lien, Uan-Kang Tan, Chun-Hwa Chen, John T.-A. Hsu, Yu-Sheng Chao, Su-Ying Wu and Hsing-Pang Hsieh. �Discovery of novel pyrazoles as Aurora kinase A inhibitors by virtual screening and structural biology studies� J Med Chem. 2009, 52(4),1050�1062.
19. 5. Gadarla Randheer Reddy, Ching-Chuan Kuo, Uan-Kang Tan, Mohane Selvaraj Coumar, Chi-Yen Chang, Chiang Yi-Kun, Su-Ying Wu, Jang-Yang Chang, Jing-Ping Liou and Hsing-Pang Hsieh. �Synthesis and Structure-Activity Relationships of 2-Amino and 2-Hydroxy-1-Aroylnaphthalenes as Potent Antitubulin Agents� J Med Chem. 2008, 51, 8163-8167.
18 Mohane S. Coumar*, Dharam P. Jindal, Giancarlo Bruni, Paola Massarelli, Randhir Singh, Amit K. Sharma, K. Nandakumar and Subhash L. Bodhankar. �Synthesis, ?-adrenergic receptor binding and antihypertensive potential of vanillin-derived phenoxypropanolamines� Ind J Chem(B), 2008, 47, 903-909.
17. Mohane Selvaraj Coumar, Jian-Sung Wu, Jiun-Shyang Leou, Uan-Kang Tan, Chung-Yu Chang, Teng-Yuan Chang, Wen-Hsing Lin, John T.-A. Hsu, Yu-Sheng Chao, Su-Ying Wu and Hsing-Pang Hsieh. �Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold� Bioorg. Med. Chem. Lett., 2008, 18, 1623-1327.
16. Mohane Selvaraj Coumar, Chung-Nien Chang, Chiung-Tong Chen, Xin Chen, Chia-Hui Chien, Ting-Yueh Tsai, Jai-Hong Cheng, Hsin-Yi Wu, Chia-Hung Han, Ssu-Hui Wu, Yu-Wen Huang, Tsu Hsu, Yu-Sheng Chao, Hsing-Pang Hsieh and Weir-Torn Jiaang. �3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes� Bioorg. Med. Chem. Lett., 2007, 17, 1274-1279.
15. Ting-Yueh Tsai, Mohane S. Coumar, Tsu Hsu, Hsing-Pang Hsieh, Chia-Hui Chien, Chiung-Tong Chen, Chung-Nien Chang, Yu-Kang Lo, Ssu-Hui Wu, Chung-Yu Huang, Yu-Wen Huang, Min-Hsien Wang, Hsin-Yi Wu, Hong-Jen Lee, Xin Chen, Yu-Sheng Chao and Weir-Torn Jiaang. �Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors� Bioorg. Med. Chem. Lett., 2006, 16, 3268-3272.
14. Hsu Tsu, Xin Chen, Chiung-Tong Chen, Shiow-Ju Lee, Chung-Nien Chang, Kuo-His Kao, Mohane S. Coumar, Yen-Ting Yeh, Chia-Hui Chien, Hsin-Sheng Wang, Ke-Ta Lin, Ying-Ying Chang, Ssu-Hui Wu, Yuan-Shou Chen, I-Lin Lu, Su-Ying Wu, Ting-Yueh Tsai, Wei-Cheng Chen, Hsing-Pang Hsieh, Yu-Sheng Chao, Weir-Torn Jiaang. �2-[3-[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A Potent, Selective, and Orally Bioavailable Dipeptide-Derived Inhibitor of Dipeptidyl Peptidase IV� J. Med. Chem. 2006, 49, 373-380.
13. Dharam Paul Jindal, Babita Singh, Mohane S. Coumar*, Giancarlo Bruni and Paola Massarelli. �Synthesis of 4-(1-oxo-isoindoline) and 4-(5,6-dimethoxy-1-oxo-isoindoline)-substituted phenoxypropanolamines and their beta1-, beta2-adrenergic receptor binding studies� Bioorg. Chem. 2005, 33, 310-324.
12. Dharam Paul Jindal, Babita Singh, Mohane S. Coumar*, Giancarlo Bruni and Paola Massarelli. "Synthesis of 4-(phthalimide) and 4-(benzamide)-substituted phenoxypropanolamines and their b1, b2-adrenergic receptor binding studies� Indian J. Chem. 2005, 44B, 1441-1445.
11. Nandakumar K, Bansal SK, Singh R, Bodhankar SL, Jindal DP, Coumar MS, Balaraman R, Bhardwaj SH. �Selective beta(1)-adrenoreceptor blocking activity of newly synthesized acyl amino-substituted aryloxypropanolamine derivatives, DPJ 955 and DPJ 890, in rats� J Pharm Pharmacol. 2005, 57, 515-519.
10. K. Nandakumar, S.K. Bansal, Randhir Singh, A.J. Mohite, S.L. Bodhankar, D.P. Jindal, Mohane S. Coumar, R. Balaraman, S.H. Bhardwaj. �Study of b adrenoreceptor antagonistic activity of DPJ 904 in rats� Pharmacology, 2005, 74, 1-5.
9. Nandakumar K, Bansal S, Bhatt LK, Bodhankar SL, Ghole VS, Coumar MS, Jindal DP. �Cardioprotective effect of newly synthesized acyl amino substituted propanolamine derivatives, DPJ 955 and DPJ 890 against isoprenaline induced myocardial necrosis� Toxicology International, 2005, 12(2), 61-66.
8. Nandakumar K, Singh R, Bansal SK, Bodhankar SL, Jindal DP, Coumar MS, Bhardwaj SH �Antihyertensive effect of newly synthetized acylamino propranolamine derivatives, DPJ 890 and DPJ 955 in hypertensive rats� Indian J. Pharmcol. 2004, 36(6), 381-382.
7. Sunil Bajad, Mohane S. Coumar, Ravi K. Khajuria, Om P. Suri, Kasturi L. Bedi. "Characterization and synthesis of a new urinary metabolite 5-[3,4-methelenedioxyphenyl]-2E,4E-penadienoic acid-N-(3-yl-propionic acid)]-amide of piperine, an omnipresent food component, by LC/NMR/MS" Eur. J. Pharm. Sci. 2003, 19, 413�421.
6. Dharam Paul Jindal, Mohane S. Coumar, Nandakumar K, Subhash Laxmanrao Bodhankar, Prasad Gopal Purohit, Kakasaheb Ramoo Mahadik, Giancarlo Bruni, Elga Collavoli and Paola Massarelli. "Synthesis, b-adrenergic blocking activity and b-receptor binding affinities of 1-substituted-3-(2-isopropyl-5-methyl-phenoxy)-propan-2-ol oxalates" Il Farmaco, 2003, 58(8), 557-562.
5. Dharam Paul Jindal, Mohane S. Coumar, Babita Singh, Mohammed Muhiyiden M.I., Girish Nilkanth Zambare and Subhash Laxmanrao Bodhankar. "Synthesis and local anaesthetic activity of 2-substituted-N-(2-diethylaminoethyl)-acetamides" Arzneimittel Forschung/Drug Research, 2003, 53(1), 34-39.
4. Dharam Paul Jindal, Babita Singh, Mohane S. Coumar*, Giancarlo Bruni and Paola Massarelli. "Synthesis of 4-(1-oxo-isoindoline)-, 4-(5,6-dimethoxy-1-oxo-isoindoline)-and 4-acetamido-substituted phenoxy-3-amino-propanederivatives and their b1-, b2-adrenergic receptor binding studies" Indian J. Chem. 2003, 42B(11), 2808.
3. Dharam Paul Jindal, Mohane S. Coumar, Giancarlo Bruni and Paola Massarelli. "Synthesis and b1-, b2-adrenergic receptor binding studies of 4-acylamino substituted phenoxypropanolamine and 5-acylamino substituted naphthyloxypropanolamine derivatives" Arzneimittel Forschung/Drug Research, 2002, 52(9), 654-663.
2. G. Vasuki, V. Parthasarathi, K. Ramamurthi, S. Mohane Coumar, and D.P.Jindal. �2-(1H-Indol-3-ylmethylene)indane-1-one� Acta Cryst. 2002, E58, o1222�o1223.
1. G. Vasuki, S. Thamotharan, V. Parthasarathi, K. Ramamurthi, S. Mohane Coumar, and D.P.Jindal. "N-(tert-Butyl)-N-[2-hydroxy-3-(2-isoprpyl-5-methylphenoxy)propyl]ammonium hydrogen oxalate" Acta Cryst. 2002, E58, o93-o94.
Publications
Publications
28th Feb 2009