Detective Conan file 595 starts new development in Detective Conan manga. Because of Conan foolishness and FBI Laziness, they let that clumsy boy, Hondo Eisuke wandering around in the hospitals, till he finally reached the hospital where Mizunashi Rena (Kir) is. FBI was hoping that he will not find Mizunashi Rena, because little in the hospital knows about her, and she was under their eyes all the time. But they never thought that the black organization had already been in the hospital, and the clumsy boy, Eisuke found one member of them sending an email to their boss. Conan discovers that Eisuke has disappeared when it has become too late! What're you going to do, Conan-kun?