Misni Misran

COLLOIDS AND SURFACES

 

 

 

 

 

 

1.      Name:             Dr Misni  Misran (Associate Professor)

                                        Department of Chemistry, Faculty of Science, University of Malaya,

                          50603 Kuala Lumpur, Malaysia.

4.      Field of Specialisation: Colloid Chemistry

5.      Date of Birth: 15th November 1967

6.      Academic/Professional and Other Qualifications Obtained:

Academic Degree	Date	University/Institution	Specialisation
Ph.D	July 1999	University of East Anglia, England	Colloid Chemistry
B.Sc / B.Sc.Honours	June 1991,1992	The Flinders University, South Australia	Chemistry
Matriculation	1986 - 1987	South Australian Matriculation, College of Preparatory Studies, UiTM	Sciences
Malaysian (Secondary) Education Certificate	1985	Sekolah Menengah Sri Mahkota, Melaka.	Sciences
Malaysian (Secondary) Lower Education Certificate	1983	Sekolah Menengah Sri Mahkota, Melaka.	Commerce
Primary Education	1974 - 1980	Sekolah Rendah Kebangsaan Paya Dalam, Melaka.	-

RESEARCH ACTIVITIES

The main interest in surfactant science stems from their amphiphilic nature. Amphiphilic molecules are composed of two parts, one of which is the polar and water soluble, while the other is non-polar and oil soluble. Owing to this dual-character these molecules possess excellent surface activity and emulsifying properties, thereby find a wide spectrum of practical applications ranging from detergent to food to cosmeceutical industries to nano-material synthesis to fabrication of photonic and phosphor materials.

Surfactants in general and glycolipids in particular have been of our interest for a number of reasons. These include low HLB value, which means they possess excellent emulsifying properties that can help produce stable emulsions, creams and foams. They are highly biocompatible and cause no or minimum adverse effect on human if applied both externally and internally. Not to mention it gives a value added to the local palm oil industries.

Among on-going research activities conducted in this laboratory are,

1. Effect of molecular rigidity on oleic and stearic-stearate monolayer.

2. Texture Study Of Polymer Blend Emulsion Stabilized By Glycolipids For Cosmetic Application.

3. Rheological study of nanoliposome in cream emulsion.

4. Formation and Equilibrium Study of Perfluoroalkylated Fatty Acid mixed with glycolipids Vesicle in Aqueous Solution.

5. Dynamics of Fatty Acid Vesicle Formation in Emulsion System.

6. Dynamics equilibrium fatty acid interfacial tension at water-oil emulsion.

7. Dynamics Of Mixed Fatty Acids/Co-surfactant Vesicles Formation For Drug Encapsulation And Slow Release Study.

8. Encapsulation And Slow Release Study of Water Soluble Drugs By Polymerics Brush-Like Chitosan Vesicles.

9. Designing nanoliposome from unsaturated long chain fatty acid—stealth lipid mixture

10. Study of Set Cement Expansion-Shrinkage Under Surface and Oil Wells Down Hole Conditions.

 

FASCILITIES

The laboratory is well-equipped with Atomic Force Microscope from Digital Instruments, Bohlin VOR and C-VOR GEMINI Rheometers, Langmuir Blodgett Film Balance KSV 5000 system 3, KRUSS Tensiometer, KRUSS Spinning-Dropped Tensiometer, Dropped Volume Tensiometer, LAUDA viscometer, Lipex extruder for nanoliposome, membrane dialyser, Leica Polarising Microscope DMRSP with Leica Qwin500 Standard software, UV-visible Spectrophotometer CARY 50 with SFA-20 Stopped-Flow, Anton Paar DMA 4500 Density Meter, Rank Brothers Capillary Electrophoresis and other general equipments.  

PUBLICATIONS

        Chapter or Part of Books/Academic Books/Encyclopedia

        Misran M., Bucak S., and Robinson B.H., Chapter 19, “Thermodynamics And Kinetics Of Spontaneous Formation and          Breakdown of Vesicles in Aqueous Media”, Comprehensive Chemical Kinetics, 1999, 37, 683 –703, / Editors: Compton R.G. and   Hancock G., Elsevier Science,  Amsterdam.

                 Refereed Academic/Professional Journals

1. Misran M., Matthews D. B, Valente P., and Hope A., “Photochemical Electron Transfer Between Methylene Blue And Quinones”, Aust. J. Chem., 1994,47, 209-216.

2. Farquhar K., Misran M., Morini P., Robinson B. H., Stytler D.C., Garret P.R., and Holtwaltz J.F., “The Kinetics And Mechanism of Micelle-Vesicle Transition In Aqueous Solution”, J. Phys. Condensed Matter, 1997, 8(47), 9397-8984.

3. Kenichi Morigaki, Peter Walde , Misni Misran and Brian H. Robinson,“Thermodynamic and kinetic stability. Properties of micelles and vesicles formed by the decanoic acid/decanoate system”., Colloids and Surfaces A: Physicochemical And Engineering Aspects.  Vol. 213, Issue 1, 4 February 2003, page 37 – 44.

4. Esam A. Elhefian, Misni Misran and Abdul Hamid Yahaya, “Study of Surface Tension of Chitosan Solutions”, Malaysian Journal of Science, Vol. 22, No. 1: June 2003, page 121-125.

5. Misran M., Chun T.K., Niraula B.B., and Kurupiah N., “Interfacial properties of paraffin oil-alcohol mixture in the presence of glycolipids: Comparison of interfacial properties of glycolipids with the interfacial properties of Brij 35P and SDS”, Malaysian Journal of Science, Vol. 22, No. 2: December 2003, page 91 – 95.

6. Misran M., King T.C., and Niraula B.B., “Rheology properties of dodecyl-  B- D-maltoside stabilized mineral oil-in-water emulsion”, Colloids and Surfaces, A: Physiochem. and Eng. Asp. 2003, Volume 231, Issues 1 – 3, 31 December 2003, page 159 – 172.

7. Misni Misran, Tan Cok King, Boris Bhola Niraula, Noraini Ahmad, “Rheological behaviour of water soluble glycolipids: A comparison of octyl-B-D-glucopyranoside and dodecyl-B-D-maltoside emulsion system”, Malaysian Journal of Science, Vol. 22, No. 2: December 2003, page 113 -126.

8. Boris B Niraula, Tham K Chun, Misni Misran, “Interfacial properties of oil-water interface in the presence of dodecyl-ß-D-glucopyranoside: comparison of interfacial and emulsifying properties of dodecyl glucopyranoside, Brij 35P and SDS”, Malaysian Journal of Science, Vol. 22, No. 2, December 2003,  page 145 – 152.

9. Boris Bhola Niraula, Tiong Ngiik Seng, Misni Misran, “Vesicles In Fatty Acid Salt- Fatty Acid Stabilized o/w Emulsion - Emulision Structure and Rheology”, Colloids And Surfaces A, Vol. 236 (2004), Page 7 – 22.

10. Boris Niraula, Tan Cok King and Misni Misran, “Evaluation of rheology property of dodecyl maltoside, sucrose dodecanoate, Brij 35p and SDS stabilized O/W emulsion: Effect of head group structure on rheology properties and the use of rheology in accessing emulsion stability”, Colloids and Surfaces A: Physiochem. and Eng. Asp., Vol. 251 (2004), Page 59 – 74.

11. B. Niraula, Tan C King, T.K. Chun and M. Misran, “Rheology properties of glycopyranoside stabilized oil-water emulsions: Effect of length of the alkyl tail bulk and concentration of the surfactant”, Colloids And Surfaces A: Physiochem. and Eng. Asp. , Vol. 251 (2004), Page 117 – 132.

12. Boris B. Niraula, T.K. Chun, Hafizrahimi Othman, M. Misran, “Dynamic Interfacial Properties of Dodecyl-ß-D-Maltoside and Dodecyl –ß-D-Fructofuranosyl-α-D-Glucopyranoside at Dodecane/Water Interface”, Colloids And Surfaces A: Physiochem. and Eng. Asp., Vol. 248 (2004), Page 157-166.

13. Suhaila Abu Bakar, Yusoff Mohd. Amin and Misni Misran, “Thermoluminescence characteristics of boron and Er³⁺ doped SiO₂”, Malaysian Jurnal of Physics, Vol. 25, No. 3&4, 2004, Page 1 – 4.

14. Boris B. Niraula, Tiong Ngiik Seng and Misni Misran “Rheology Study of Fatty Acid Vesicle in Oil-Water Emulsion” The Malaysia Journal Of Analytical Sciences,Vol. 9, No. 1&2, 2005, Page 34-50.

15. M.Laws, A.Riyami H.Soek, J.Edwards, Y.Elmarsafawi, S.Abdenour, D.Valstar, M.Misran and A.Hassan.“Special Cement System and Cementing Techniques Improve Zonal Isolatioon in South Oman Fields” , The 2006 SPE Annual Technical Conference and Exhibition, 24-27 September 2006 San Antonio, Texas.

16. El-Marsafawi, Y., Al-Yami, A., Nasr-El-Din, H.A., Al-Jeffri, A., Misran, M., Hasan, A., Jain, B. 2006. A new cementing approach to improve and provide long-term zonal isolation , Proceedings - SPE Asia Pacific Oil and Gas Conference and Exhibition 2006: Thriving on Volatility 1, vol 1, pp. 52-65.

17. Esam A El-Hefian, Misni Misran, Abdul Hamid Yahaya, Effect of Temperature and Storage Time on The Viscosity of Chitosan Solution”, University Buleletin, Seventh April University, 2004, Vol 6. 110-115

18. M R Reisi, M Misran and C H Chuah, “Organotin Componds and Environment”, Caspian J. Env. Sci. 2006, Vol. 4 (2), 148-152.

19. Jean Ne Cheong, Chin Ping Tan, Yaakob B. Che Man, Misni Misran, α-Tocopherol nanodispersions: Preparation, characterization and stand stability evaluation, Journal of Food Engineering, Volume 89, Issue 2, November 2008, Pages 204-209.

20. P.F.Leea , W.A.T.Wan Abdullaha and Misni Misran , Surface Charge Comparison of Liposome and TiO2 , Indian Journal :Biochemistry, In the process of publishing Accepted in 6 January 2008.

21.  

22. 

23.  

 

Public Speaker/Lecture

· Misni Misran, “Nanomedical Technology”, National Symposium on Science & Technology 2003 : Strategic Research and Innovation Towards Economic Development, 28 – 30 July 2003, Palace of Golden Horses Hotel, Seri Kembangan, Selangor.  Invited Speaker.

· Misni Misran, Muhamad Rasat Muhamad, “Achieving Excellence in Condensed Matter Research in Malaysia”, Special Forum with Nobel Laureate Prof. Gerardus T’Hooft (Nobel Prize Physics, 1999) in conjunction with “The Nobel Prize Centennial Exhibition”, 6 March 2004, Universiti Sains Malaysia, Penang.  Invited Speaker.

· Misni Misran, “Nanotechnology In Science & Engineering” in Young Engineer’s Symposium 2004, 18 July 2004, Kuliyyah of Engineering, International Islamic University Malaysia (IIUM).  Invited Speaker.

· Misni Misran, “Dynamics of Vesicle Formation”, Seminar Biomaterials, Biotechnology and Nanotechnology”, organized by SIG-Biotherapeutic and Healthcare Products (BIOHCP) and UiTM Shah Alam, 27 September 2004, Hotel Grand Blue Wave, Shah Alam, Selangor.  Invited speaker.

· Misni Misran, “Nanotechnology in Medicine: Vesicles for drug targeting vehicles”, Regional Conference on Molecular Medicine 2005, 10 September 2005, Palace of Golden Horses, Kuala Lumpur.  Invited Speaker.

· Misni Misran, “Thin Film & Surface”, Seminar & Workshop: Technique for characterization of liquid and solid interface, 13 September 2005, The Summit Hotel, UEP Subang Jaya, Selangor.  Invited Speaker.

· Misni Misran, “Nanobiotechnology – Liposomes as Drug Transport Vehicles”, Biotechnology Talk – An Awareness Programme, 24 January 2006, Crown Princess Hotel, Jalan Tun Razak, Kuala Lumpur.  Invited Speaker.

· Misni Misran, “Nanoliposomes :From Palm oil to Drug delivery Vehicles”, Faculty of Science and Technology, UKM, March 2007.

 

 

 

 

                                 R=0.12                          R=0.18                         R=0.24

                               Fig. TEM of  CaSiO3-MgSiO3:Eu2+ after  calcined at  800C

 

                       LECTURE NOTES

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Academic Awards

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

             PATENTS

(i)                          Title     : Particle Entrapment By Fatty Acid Liposome

                  Ref       : PI 20062574

                  Filing date: 5^th June 2006.

(ii)            Title     : An oil-in-water cream emulsion composition

                  Patent Application Number: PI20054885

                  Filing date: 18^th October 2005.

(iii)           Title     : Emulsion Composition with Improved Stability

             Patent Application Number: PI20044060

             Filing Date : 14^th  December 2004            

 

                                                                                            NEW PAGE

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Contact:

 Email: [email protected]

Tel/fax: 006 03 79674079

Last Updated: 15th  MARCH -2007