Stephen Paddock has several indicators of Multiple Chemical Sensitivity including various biomarkers reported by the Stanford brain autopsy. Since I wrote this report, the prevalance rate has been updated to 25.9% of the U.S. population affected according to the study below.
[NEW!] Chemical Sensitivity linked to Fibromyalgia... Classes 1 and 2 reflect the current concepts and major patient profile for FM. The identification of Classes 3 and 4, with a greater variety of symptoms and body regions affected, expands the concept of FM as a disease continuum rather than a set of symptoms that can be discretely evaluated and emphasizes the need for an individualized approach to diagnosis and treatment.
Class 3 is associated with more advanced comorbidities, with further increases in pain relative to Classes 1 and 2. Class 3 patients are also characterized by a clear prevalence of sleep disturbance and potential chemical sensitivity that is manifested by a latex allergy as previously reported.
In contrast to Classes 1–3, Class 4 has the highest prevalence and severity of widespread pain and symptoms. Class 4 appears to represent FM that is secondary to other diseases such as multiple sclerosis and lupus, which have a high prevalence in this class.
By confirming the presence of genes which are activated by chemicals, this study puts the theory of limbic kindling on a stronger foundation. Certain genes cause harm to the host when exposed to certain chemicals. Two genes work in tandem. One does the work and the other turns it on. In the Zebrafish, those that had both genes when exposed to the test chemicals grew twisted facial features.
Among the population, 12.8% report medically diagnosed MCS and 25.9% report chemical sensitivity. Here is a link to Anne Steinemann's website
This is a landmark study by Rossi and Pitidis. A systematic bibliography analysis of about the last 17 years on multiple Chemical sensitivity (MCS) was carried out in order to detect new diagnostic and epidemiological evidence. They divided formally the progressive stages.
We would like to report on the considerable difficulty in establishing the causal relationship between exposures to small amounts of chemical substances in the environment compared to large amounts.
The nature of contested illness is such that it has not yet fully entered the official diagnostic code and hegemonic thinking of mainstream medical care. Hence patients are not uniformly seen as having legitimate physical illness and they face disbelief and psychological attributions from others while the mainstream medical system debates the validity of the condition. Here is a link to Dr. Gibson's MCS research unit at James Madison University.
This 1992 report is the original source of all the MCS controversy. It comes from a workshop conducted at the request of the Environmental Protection Agency. This volume contains the papers prepared and presented by individual workshop participants: the papers have not undergone peer review. This was the opening salvo in a war which has lasted since 1992 between environmentalists and big chemical. The chemically sensitive population has been caught in the crossfire ever since.
A key reaction in the limbic system of the brain which acts as an "amplifier" to turn small doses of toxins into a full scale reaction involves reactive oxygen species (ROS). Free radicals promote redox reactions, altering biomolecules and damaging cell components. ROS can react directly with lipids, proteins, enzymes and DNA, altering them.