BIOL1551 section 01, Principles of Biology I

Midterm Oct 21st, 2002

 

Student Number ____________________

 

Student Last Name __________________

 

Student First Name __________________

 

Before exam

·        You need #2 pencils (sharpened) and an eraser.  Notify the instructor if you did not bring pencils.

·        Seat in alternative rows (as directed by the instructor).

·        Do not open the question book until you are told.

·        On the computer answer sheet, write down your name (Last name, First name) and your student number.  Write down the course and section number (155101).

·        Write down your name and student number on the front page of the question book.

 

During exam

·        Circle answers on the question book and then transfer your answer to the computer sheet.  (Both the question book and the computer sheet will be collected.)

·        For each question, make sure the circle is completely filled.

·        Erase mistake cleanly.

·        Do not make any other marks on the computer sheet.  You may use the question book to sketch out things.

·        Notify the instructor if you ruin your answer sheet.  You will need to reenter a new answer sheet.

·        Make sure to answer all questions.  No penalty for wrong answers.

·        Do not leave the classroom until you are finished.

·        The exam should finish at 11:20 am.

 

After exam

·        Hand in both the question book and the computer answer sheet.

 

List ambiguous questions here _________________________________________.
MULTIPLE CHOICES.  Choose the one alternative that best completes the statement or answers the question.

 

1)      If an insecticide kills 95 % of an insect population, you would expect the subsequent generations of the insects __________.  (Chapter 1, web activity)

A) to die out due to the drastic decrease in population size.

B) to proliferate faster than the original generation.

C) to have the same proportion of insecticide-resistant insects as the original generation.

D) to have a higher percentage of insecticide-resistant insects than the original generation.

E) to have a lower percentage of insecticide-resistant insects than the original generation.

Answer: D

 

2)      Multicellular eukaryotic organisms that lack cell walls are ______. (Chapter 1 and 4)

A) Domain Bacteria

B) Domain Archaea

C) Kingdom Animalia

D) Kingdom Plantae

E) Kingdom Fungi

Answer: C

 

3)      Which element is the least abundant in living organisms? (Chapter 2)

A) hydrogen (H)          

B) oxygen (O)

C) sodium (Na)           

D) nitrogen (N)

E) carbon (C)

Answer: C

 

4)      The hydrogen atoms of a water molecule are bonded to the oxygen atom by __________ bonds, whereas neighboring water molecules are held together by __________ bonds.  (Chapter 2)

A) ionic......................covalent

B) hydrogen...............polar covalent

C) polar covalent.......ionic

D) polar covalent.......hydrogen

E) hydrogen...............ionic

Answer: D

0.5 point is given to those who answered C


 

5)      You now know that the old cliché "oil and water don't mix" is true. Why? (Chapter 2 and 3)

A) Water is hydrophobic. 

B) Water exhibits polarity and oil does not.

C) Oil exhibits polarity and water does not.

D) Oil is hydrophilic.

E) None of the above.

Answer: B

 

6)      Figure 1 (see the last page) is the general structure of _________, which contain the two functional groups __________ and ___________. (Chapter 3)

            A) amino acid ............. amino group...............carboxyl group

            B) amino acid ..............amino group ..............hydroxyl group

            C) glucose ....................carbonyl group...........hydroxyl group

            D) glucose.....................amino group...............carboxyl group

            E) nucleic acid ..............carbonyl group..........hydroxyl group

Answer: A

 

7)      Which of the following carbohydrates is disaccharide? (Chapter 3)

A) glucose        B) fructose       C) sucrose        D) cellulose      E) ribose

Answer: C

 

8)      The storage form of carbohydrates in animals is __________ and in plants is __________.  (Chapter 3)

A) starch . . . glycogen

B) sucrose . . . glycogen

C) glycogen . . . cellulose

D) glycogen . . .  starch

E) cellulose . . . glycogen

Answer: D

0.5 point is given to those who answered C.

 

9)      A diet high in animal products may increase the risk for heart disease. This is because ____________. (Chapter 3)

A) most animal fats are unsaturated.

B) most animal fats are hydrogenated oils.

C) most animal products contain high levels of phospholipids.

D) most animal fats are saturated.

E) most animal products contain high levels of anabolic steroids.

Answer: D


 

10)  Amino acids can be distinguished from one another by __________. (Chapter 3)

A) the chemical properties of their R groups.

B) the type of bond between the R group and the rest of the amino acid molecule.

C) the chemical properties of their amino and carboxyl groups.

D) the number of R groups found on the amino acid molecules.

E) All of the choices are correct.

Answer: A

 

11)  The tertiary structure of a polypeptide refers to ____________. (Chapter 3)

A) its size.

B) its amino acid sequence.

C) the presence of pleated sheets.

D) the overall three-dimensional structure.

E) the number of R groups it contains.

Answer: D

 

12)  If one strand of DNA has the sequence TATACTGC, what is the nucleotide sequence of the complementary strand? (Chapter 3)

A) TATACTGC

B) UAUACUGC        

C) AUAUGACG

D) CGCGTCAT

E) ATATGACG

Answer: E

 

13)  Which one of the following is the proper matching of a polymer and the monomer it is made from? (Chapter 3)

A) nucleic acid ...............sugar

B) triglyceride ................steroid

C) protein .......................amino acid

D) polysaccharide ..........starch

E) wax ............................fat

Answer: C

 

14)  Epithelial cells in small intestine prevent contents of intestine from leaking into the surrounding tissues.  The cell junctions that would facilitate this are ________. (Chapter 4)

A) tight junctions

B) anchoring junctions

C) communicating junctions

D) plasmodesmata

E) extracellular matrix

Answer: A

 

15)  Which one of the following is NOT a component of the endomembrane system? (Chapter 4)

A) chloroplast               B) Golgi apparatus        C) nuclear envelope     

D) lysosomes                E) smooth ER

Answer: A

 

16)  The cell shown in Figure 2 (see the last page) is ___________ because it contains a nucleus and does not have _________. (Chapter 4)

A) a bacterial cell..............mitochondria

B) an animal cell...............lysosomes

C) an animal cell...............chloroplasts

D) a plant cell....................mitochondria

E) a plant cell.....................central vacuoles

Answer: C

0.5 point is given to those who answered B or E.

 

17)  Identify the structure shown in Figure 3 (see the last page). (Chapter 4)

A) nucleus                    B) rough ER                 C) smooth ER             

D) mitochondrion          E) Golgi apparatus

Answer: E

 

18)  The two main functions of the rough endoplasmic reticulum (rough ER) are the production of ________. (Chapter 4)

A) mitochondria and proteins that are to be secreted by the cell.

B) chromatin and mitochondria.

C) more membrane and proteins to be secreted by the cell.

D) hydrogen peroxide and lipids secreted by the cell.

E) ribosomes and steroid hormones.

Answer: C

 

19)  Which of the following choices best describes the route of a secretary protein from its production to its exit from the cell? (Chapter 4)

A) rough ER, mitochondria, transport vesicles, cell membrane

B) nucleous, transport vesicles, Golgi apparatus, central vacuoles, cell membrane

C) rough ER, transport vesicles, smooth ER, ribosomes, cell membrane

D) rough ER, transport vesicles, Golgi apparatus, transport vesicles, cell membrane

E) smooth ER, lysosomes, transport vesicles, cell membrane

Answer: D


 

20)  Which of the following statements does NOT describe similarities between chloroplasts and mitochondria?  Choose E if all of the statements are correct.  (Chapter 4)

A) They are surrounded by double membranes.

B) They contain electron transport chains.

C) They contain DNA.

D) They share similarities to prokaryotic cells.

E) All of the above statements are correct.

Answer: E

This question was rejected as a ‘bad question’ from a statistical analysis.  Instead of eliminating the question, I decided to keep it as a “bonus” question.  This way, those who answered correctly get rewarded while those who didn’t don’t lose any point.  By the way, 40 % of you answered correctly in this question.

 

21)  The cells which produce lipids contain a lot of _________. (Chapter 4)

A) nuclei

B) lysosomes

C) peroxisomes

D) smooth ERs

E) ribosomes

Answer: D

 

22)  Heating inactivates enzymes by ________. (Chapter 3 and 5)

A) causing enzyme molecules to stick together.

B) breaking the covalent bonds that hold the molecule together.

C) removing phosphate groups from the enzyme.

D) changing the enzyme's three-dimensional shape.

E) None of the choices are correct.

Answer: D

 

23)  What is the most likely optimal temperature for human enzymes? (Chapter 5)

A)    7 oC

B)     17 oC

C)    27 oC

D)    37 oC

E)     47 oC

Answer: D

 

24)  Phospholipid molecules in a membrane are arranged with their __________ on the exterior and _________ on their interior. (Chapter 5)

A) hydrophilic tail ................ hydrophobic head

B) hydrophilic head............... hydrophobic tail

C) nonpolar tail ..................... polar head

D) hydrophobic tail................ hydrophilic head

E) hydrophobic head.............. hydrophilic tail

Answer: B

25)  Which of the followings most accurately describe enzymes?

A)  Enzymes are mainly made of carbohydrates.

B)  Since an enzyme binds to its substrate at the enzyme’s active site, the shape of the enzyme is altered irreversibly after each reaction.

C)  Most enzymes facilitate chemical reactions by coupling them with the hydrolysis of ATP

D) The shapes of enzymes can be altered any ways without affecting their catalytic activities

E)  Enzymes facilitate chemical reactions by lowering the energy of the activation (EA)

Answer: E

 

26)  ATP can be used as cell’s energy currency because __________. (Chapter 5)

A)  the formation of ATP is an exergonic (energy generating) reaction

B) exergonic (energy generating) reaction can be fueled by coupling them with the synthesis of ATP from ADP

C) endergonic (energy requiring) reactions can be fueled by coupling them with the synthesis of ATP from ADP.

D) endergonic (energy requiring) reactions can be fueled by coupling them with the hydrolysis of ATP.

E) ATP lowers the energy of activation (EA), thereby facilitating chemical reactions.

Answer: D

 

27)  If the volume of an animal cell increases when it is placed in an aqueous solution, that solution is said to be __________ to the cell.  Plant cells may be __________ in this solution. (Chapter 5)

A) hypotonic  ...............turgid

B) hypertonic ...............turgid

C) isotonic ...................flaccid

D) hypotonic ............... lysing

E) hypertonic............... lysing

Answer: A

0.5 point is given to those who answered B or D.

 

28)  People with hypercholesterolemia carry fewer LDL receptors on the cell surface than healthy individuals.  Cholesterol containing particles accumulate in their blood vessels because __________. (Chapter 5)

A)    they cannot produce enough HDL.

B)     they do not exercise enough.

C)    they require diet rich in saturated fat.

D)    they cannot breakdown saturated fat in their body.

E)     the intake of LDL particles to the cell is much slower.

Answer: E

 

29)  The act of a white blood cell engulfing a bacterium is _________. (Chapter 5)

A) diffusion.                  B) pinocytosis. C) phagocytosis.          

D) osmosis.                  E) receptor-mediated endocytosis.

Answer: C

30)  The concentration of calcium in a cell is 0.3%. The concentration of calcium in the surrounding fluid is 0.1%. How could the cell obtain more calcium? (Chapter 5)

A) passive transport      B) active transport        C) diffusion      

D) exocytosis               E) osmosis

Answer: B

 

31)  Which of the followings is a proper matching of a cellular process and its location? (Chapters 4, 6 and 7)

A)    the Calvin cycle ............................... matrix of mitochondria

B)     electron transport chains................... cristae of mitochondria

C)    protein synthesis .............................. lysosome

D)    the Krebs cycle................................. grana of chloroplasts

E)     light reactions .................................. cytoplasmic fluid

Answer: B

32)  In cellular respiration, chemical energy in glucose is released by _________ reactions.  This energy is used for __________ reactions of generating ATP.  During this process, about __________ % of chemical energy in glucose is converted into ATP (Hint: Estimate the chemical energy output assuming that the chemical energy of ATP is about 1 % of that of glucose.) (Chapter 6)

A)    endergonic ............exergonic ...............5

B)     endergonic........... exergonic ..............40

C)    endergonic ............exergonic .......... 100

D)    exergonic ..............endergonic  ....... ..40

E)     exergonic ............. endergonic..............5

Answer: D

0.5 point is given to those who answered B or E

33)  During the reaction 6CO2 + 6H2O ® C6H12O6 + 6O2, carbon dioxide is __________ to make glucose and water is ___________ to give out oxygen.  This process occurs in ___________. (Chapter 4, 6 and 7)

A)    reduced ...........oxidized............chloroplasts

B)     reduced ...........oxidized............mitochondria

C)    oxidized ..........reduced ............chloroplasts

D)    oxidized ..........reduced ............mitochondria

E)     oxidized ..........reduced ............cytoplasmic fluid

Answer: A

0.5 point is given to those who answered B or C.


 

34)  In cellular respiration, oxygen (O2) is consumed during _____. In photosynthesis, oxygen is produced during ______. (Chapters 6 and 7)

A)    glycolysis...........................the light reaction

B)     the Krebs cycle ..................the Calvin cycle

C)    electron transfer chains......the light reaction

D)    electron transfer chains......the Calvin cycle

E)     the Krebs cycle .................the light reaction

Answer: C

0.5 point is given to those who answered A, D or E.

35)  A glucose molecule is completely broken down in glycolysis and the Krebs cycle, but these two processes yield only a few ATPs. Where is the rest of the chemical energy that the cell obtains from the glucose molecule? (Chapter 6)

A)    in pyruvic acid

B)     in NADH and FADH2

C)    in ADP

D)    in the carbon dioxide molecules released by the processes

E)     in the oxygen used in the electron transport chains

Answer: B

36)  Which of the following processes produces the most NADHs? (Chapter 6)

            A) alcoholic fermentation

            B) lactic acid fermentation

            C) glycolysis

            D) the Krebs cycle

            E) electron transport chains and chemiosmosis

Answer: D

 

37)  Which of the following processes produce the most ATPs? (Chapter 6)

A) alcoholic fermentation

            B) lactic acid fermentation

            C) glycolysis

            D) the Krebs cycle

            E) electron transport chains and chemiosmosis

Answer: E


 

38)  When muscle tissues were functioning anaerobically (without oxygen), they accumulate ___________. (Chapter 6)

A)    ATP

B)     glucose

C)    lactic acid

D)    ethanol

E)     carbon dioxide

Answer: C

 

39)  During chemiosmosis in cellular respiration, ATP synthase generates ATP from ADP. The energy needed for this reaction comes from _____.  (Chapter 6)

A)    concentration gradient of sodium ions (Na+)

B)     energy released during glycolysis

C)    the fermentation of pyruvic acid to form lactic acid

D)    the movement of hydrogen ions (H+) from the intermembrane space to the mitochondrial matrix

E)     energy released during the Krebs cycle

Answer: D

 

40)  The process of breaking down glucose to pyruvic acid is called ____________.  In this process, ATP is generated via _____________. (Chapter 6)

A)    fermentation...........chemiosmosis

B)     glycolysis...............chemiosmosis

C)    glycolysis ..............substrate-level phosphorylation

D)    the Krebs cycle......substrate-level phosphorylation

E)     fermentation...........substrate-level phosphorylation

Answer: C

0.5 point is given to those who answered B, D or E.

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