Review Questions Dec 02

 

1. Embryonic stem (ES) cells have greater potential for use in the treatment of disease than adult stem cells because________?

A. they are larger and thus easier to work with than other cells.

B. they are the most highly differentiated of all cell types.

C. they have potential to differentiate a many more different types of cells.

D. they are arrested at the G1 phase of the cell cycle.

E. they retain nutritional reservoirs from mother.

 

2. Embryonic stem cells are obtained from __________.

A. early embryos (blastocyst)

B. fetus after 20 weeks of pregnancy

C. new born baby

D. bone marrow cells in adult

E. unfertilized egg

 

3. It is much easier to clone plants than animals because _________.

A. plants may be regenerated from a single somatic cell

B. mature plants retain ability to dedifferentiate

C. most mature animal cells do not divide

D. plants can reproduce asexually

E. all of the above

 

4. Which one of the following best describes cancer cells?

A. Proto-oncogenes control their cell division.

B. They will divide 20 to 50 times and then stop.

C. They are more highly differentiated than normal cells.

D. Normal controls over cell division have been altered.

E. Tumor-suppressor genes control their cell division.

 

5. A proto-oncogene may turn into an oncogene when _________.  An oncogene ________.

A. crossing over occurs ......................................slows down cell division

B. an activator binds to the oncogene ................ stimulates cell division

C. a mutation(s) occurs to the proto-oncogene... stimulates cell division

D. an inhibitor binds to the proto-oncogene........ slows down cell division

E. a tumor-suppressor gene fails to function....... stimulate cell division

 

6. The protein called p53 is a transcription factor which stimulates the expression of genes that inhibit cell division.  When a mutation in the p53 gene results in the loss of the p53 protein, __________.  The p53 gene is an example of __________.

A. cell division is arrested .............. oncogene

B. cell division is stimulated............ tumor-suppressor gene

C. cell division slows down ............ proto-oncogene

D. cell division is stimulated ..........  proto-oncogene

E. cell division slows down.............. tumor-suppressor gene

 

7. Most human cancers are __________.

A. caused by the accumulation of mutations

B. caused by viruses

C. inherited from one parent, like an autosomal dominant

D. inherited from both parents, like an autosomal recessive

E. caused by radiation

 

8. The leading cause of cancer in North America is __________.

A. UV radiation

B. tobacco

C. viruses

D. dietary fat

E. X-ray radiation

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