MCQs Answers
1. Influenza A virus:
a. T
b. F: large part of replication takes place in nucleus.
c. T
d. F: re-infection is common.
e. T
2. All enveloped negative sense RNA viruses:
a. F
b. T
c. F
d. T
e. F
3. Laboratory diagnosis of congenital infection is achieved by demonstrating specific antibody:
a. F
b. F
c. F
d. T
e. F
4. Respiratory syncytial virus is:
a. F
b. F
c. T
d. T
e. F
5. Adenovirus infections are the usual causes of:
a. T
b. F
c. T
d. F
e. F
6. Herpes simplex virus:
a. F
b. T
c. T
d. T
e. F
7. Varicella-Zoster:
a.
b. F
c. T
d. T
e. F: only in EBV.
8. Vaccination against measles:
a. T
b. F
c. F
d. T: due to the measles vaccine.
e. F: not given to pregnant women.
9. Rabies exposure:
a. T
b. F
c. T
d. F: the virus has a long incubation of between 2 to 16 weeks.
e. T
10. Viruses particularly associated with haemorrhagic fever:
a. T
b. T
c. F
d. F
e. T
11. Virus morphology under EM is diagnostic of:
a. F
b. F
c. T
d. F
e. T
12. HIV-1 gp120:
a. F
b. F: binds to CD4 receptor.
c. F
d. T
e. F
13. Effective against CMV retinitis:
a. F
b. F
c. F
d. F
e. T
14. Enterovirus:
a. T
b. T
c. F
d. F
e. T
15. Lab findings on CSF consistent with viral meningitis:
a. F
b. T
c. F
d. T
e. T
16. Disease attributed to prions which resist chemical & physical treatments that are capable of destroying nucleic acids:
a. F: Human polymavirus JC.
b. T
c. T
d. F: measles & rubella.
e. T
17. Clinical manifestations of HIV seroconversion:
a. F
b. F
c. T
d. T
e. T
18. Possible means of diagnosis of congenital HIV infection in neonate born to an infected mother is:
a. F
b. T
c. F
d. T
e. F
19. Of Rotaviruses:
a. F
b. T
c. F
20. The following hepatitis viruses are RNA viruses:
a. T
b. F
c. T
d. T
e. F
21. True for anti-oncogenes:
a. F
b. T
c. T
d. T
e. F
22. Direct and non-direct transforming RNA tumor viruses differ in:
a. T
b. T
c. F
d. T
e. T
23. The majority of hepatitis B infections:
a. T
b. T
c. F
d. F
e. T
24. Dengue virus:
a. T
b. F: they share antigens.
c. T
d. T
e. T
25. The clinical criteria for diagnosis of dengue haemorrhagic fever include the following:
a. T
b. T
c. T
d. T
e. F
26. The triple vaccine for the prevention of virus infections includes protection against:
a. F
b. F
c. F
d. T
e. T
27. Rotavirus infections:
a. F: less common than in children, but outbreaks of infection are not rare in adults.
b. F: virus cannot be cultured. Diagnosis by EM.
c. T: diarrhea is self-limiting.
d. F
e. T
28. The following have oncogenic properties in humans:
a. T
b. F
c. F
d. F
e. F
29. In a suspected case of poliomyelitis, the most important specimens to be taken for the isolation of the
virus are:
a. T
b. T: but less often than faeces.
c. F
d. F
e. F
30. The following are at high risk of HIV infection:
a. F
b. T
c. T
d. F
e. T
31. Atypical lymphocytosis may be a feature of:
a. T
b. F
c. T
d. T
e. T
32. The following may cause latent infections:
a. T
b. F
c. T
d. F
e. T
33. Immunization against hepatitis B infection will also protect against infection by the following viruses:
a. F
b. F
c. T
d. F
e. F
34. Hepatitis C virus:
a. T
b. T
c. T
d. T
e. F
35. Hepatitis A virus infection:
a. F: 5 to 14 days.
b. F
c. F
d. T
e. T
36. A raised titre of anti-HBs in the blood:
a. T
b. T
c. T
d. F
e. F
37. Reliable diagnosis of the following virus infections may be made in the laboratory within 24 hours of receiving the appropriate specimen:
a. T: by direct immunofluorescence.
b. T: EM.
c. T: direct immunofluorescence.
d. F
e. T: detection of presence of inclusion bodies.
38. The herpes group of viruses include:
a. T
b. F
c. F
d. T
e. T
39. Zoonoses of viral aetiology include:
a. T
b. F
c. F
d. T
e. T
40. Viruses associated with the production of vesicular lesions:
a. F
b. T
c. T
d. F
e. F
41. Genial herpes infection:
a. T
b. F
c. F: often asymptomatic.
d. F: infection usually occurs perinatally.
e. F
42. The following are examples of DNA viruses:
a. T
b. T
c. F
d. F
e. T
43. The following virus infections are transmitted by the faeco-oral route:
a. T
b. F
c. F
d. F
e. T
44. The following are true of immunization:
a. F
b. T
c. T
d. F
e. T
45. Poliomyelitis:
a. T
b. T: mainstay of laboratory diagnosis is viral isolation from throat swab or stool sample.
c. T
d. T
e. F: used in pregnancy or immunocompromised.
46. The following are examples of 'prion' diseases:
a. F
b. T
c. F
d. T
e. F
47. Viruses that can cause sexually transmitted diseases include:
a. F
b. T
c. F
d. F
e. T
48. Complications of measles include:
a. T
b. T
c. F
d. F
e. F
49. In influenza:
a. T
b. F
c. T
d. F: only for influenza A.
e. T
50. Bovine spongiform encephalopathy:
a. F
b. F
c. F
d. T
e. F
51. Rabies:
a. F
b. T
c. T: but rarely.
d. F: human diploid cell culture.
e. T
52. Acute gastroenteritis commonly accompanies infection with the following:
a. F
b. F
c. F
d. T
e. F
53. The common cold syndrome may be caused by:
a. F
b. T
c. T
d. F
e. T
54. In hepatitis A infections:
a. F
b. F
c. T
d. F
e. T
55. Viral hepatitis may be caused by:
a. F
b. T
c. T
d. F
e. F
56. Mumps:
a. T
b. T
c. T
d. T
e. F
57. Children with the following conditions should not be given the MMR vaccine:
a. F
b. T: history of anaphylaxis after eating eggs.
c. F
d. F
e. F
58. Hepatitis B:
a. T
b. T
c. F
d. T
e. F: vaccine consists of surface antigen absorbed onto aluminum hydroxide.
59. Viruses causing vesicular rashes are:
a. T
b. F
c. F
d. T
e. F
60. Herpes simplex virus is associated with:
a. T
b. T
c. T
d. T
e. F: usually as a result of disseminated infections.
61. Enveloped DNA viruses include:
a. T
b. F
c. T
d. T
e. F
62. Non-enveloped DNA viruses include:
a. T: envelope is present.
b. T
c. T
d. F
e. F
63. RNA viruses include:
a. F
b. T
c. T
d. T
e. T
64. Agents that interfere with viral multiplication include:
a. F
b. T
c. F
d. T
e. T
65. Varicella zoster virus:
a. T
b. F: diagnosis is established by serology.
c. T: rare but well recognized cases.
d. F
e. T
66. The following can be used for skin disinfection:
a. F: only weak antiseptic activities.
b. F
c. F
d. T
e. T
67. Respiratory syncytial virus:
a. F
b. T
c. T
d. T
e. T
68. Treatment with acyclovir:
a. T
b. F
c. F: may be used with caution in pregnancy.
d. T
e. F: rare.
69. In HIV infections:
a. T
b. F
c. T
d. F
e. F: there is polyclonal activation of B cells in response to infection with HIV and associated opportunistic pathogens.
70. HIV is reliably inactivated by:
a. T
b. T
c. F: chlorhexidine is effective but does not guarantee complete elimination of HIV.
d. T
e. T
71. Gamma irradiation can be used to sterilize:
a. T
b. F
c. T
d. T
e. F
72. Factors affecting the performance of a disinfectant are:
a. T
b. T
c. T
d. T
e. T
73. Plantar warts:
a. T
b. F
c. F: immune response is ineffective.
d. F
e. F
74. Viruses associated with conjunctivitis include:
a. T
b. T
c. T: ophthalmic zoster.
d. F: chorioretinitis, not conjunctivitis.
e. F