POXVIRUSES

 

1.            Virology

 

a.         They are double-strand DNA viruses.

 

b.         They are large particles with two morphological types:

 

i.          large, brick-shaped (vaccinia, molluscum contagiosum)

 

ii.          large, oval with criss-cross surface bonding (orf, paravaccinia).

 

 

2.         List of Poxviruses

 

 

Poxvirus

Natural host

Disease

Smallpox

Humans

Febrile disease with widespread vesicular lesions.

Molluscum contagiosum

Humans

Low-grade infection characterized by reddish, waxy papules on skin.

Orf

Sheep, goats

Chronic granulomatous lesions

Monkeypox

Monkeys, squirrels

Mild smallpox

Tanapox

Monkeys

Scanty vesicular lesions on skin which do not progress to pustules.

 

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