Warts
1.
Warts are benign tumors of the skin, with virus-induced proliferation of
keratinized and non-keratinized squamous epithelium – i.e. both skin and
mucous membranes.
2.
Human papillomaviruses and the poxvirus molluscum contagiosum are the
viruses responsible for genital warts.
3.
Clinical Features:
a.
Common warts: most common on hands and feet, they also affect the
genitalia and anus, where they may be large and are known as condylomata
acuminata.
b.
Condylomata acuminata:
i.
a sexually-transmitted disease, in which the warts are occasionally
large.
ii.
rarely, and only in the immunocompromised, they become malignant, with
change to invasive squamous epitheliomata.
c.
Laryngeal papilloma: the juvenile form is acquired during birth
from maternal condylomata acuminata, there is a tendency to recur after
treatment.
4.
Human warts and Papillomaviruses
|
Wart |
Papillomavirus
type |
|
Plantar |
1,
4 |
|
Hand |
2 |
|
Flat;
juvenile |
3,
10 |
|
Condylomata
acuminata |
6,
11 |
|
Carcinoma
of cervix |
16,
18, 31 |
|
Laryngeal |
6,
11 |