Warts

1.         Warts are benign tumors of the skin, with virus-induced proliferation of keratinized and non-keratinized squamous epithelium – i.e. both skin and mucous membranes.

 

2.         Human papillomaviruses and the poxvirus molluscum contagiosum are the viruses responsible for genital warts.

 

 

3.            Clinical Features:

 

a.            Common warts: most common on hands and feet, they also affect the genitalia and anus, where they may be large and are known as condylomata acuminata.

 

b.            Condylomata acuminata:

 

i.          a sexually-transmitted disease, in which the warts are occasionally large.

 

ii.          rarely, and only in the immunocompromised, they become malignant, with change to invasive squamous epitheliomata.

 

c.            Laryngeal papilloma: the juvenile form is acquired during birth from maternal condylomata acuminata, there is a tendency to recur after treatment.

 

 

 

4.         Human warts and Papillomaviruses

 

Wart

Papillomavirus type

Plantar

1, 4

Hand

2

Flat; juvenile

3, 10

Condylomata acuminata

6, 11

Carcinoma of cervix

16, 18, 31

Laryngeal

6, 11

 

 

 

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