SMALL ROUNDED STRUCTURED VIRUSES (SRSVs)

Structure & Property	Transmission	Pathogenesis	Clinical findings	Laboratory diagnosis	Treatment	
Family: calicivirus

Genome: single-strand RNA, positive polarity

	Fecal-oral

Virus is excreted in feces for only up to 72h		Incubation period: 24-48hr

Abdominal cramps

Vomiting

	Detected by EM of stools.

PCR is now used to detect SRSV RNA in stools.

Do not grow in cell culture.	No antiviral therapy or vaccine available.