- "The Lone Gunmen Opening Theme"
Written by: Mark Snow
Performed by: session musicians
- "Cross the Line"
Performed By: Cuba
Episode: 1.01. Pilot
- "Switchblade"
Performed By: Link Wray
Episode: 1.02. Bond, Jimmy Bond
- "Ca Plane Pour Moi"
Performed by: Plastic Bertrand
Episode: 1.03. Eine Kleine Frohike
- "Bad to the Bone"
Performed by: George Thorogood
Episode: 1.03. Eine Kleine Frohike
- "455 Rocket"
Performed by: Kathy Mattea
Episode: 1.04. Like Water For Octane
- "Soulville"
Performed by: on-camera band
Episode: 1.05. Three Men and a Smoking Diaper
- "Oh Happy Day"
Performed by: on-camera band
Episode: 1.05. Three Men and a Smoking Diaper
- "Say a Little Prayer"
Performed by: on-camera band
Episode: 1.05. Three Men and a Smoking Diaper
- "Natural Woman"
Performed by: Aretha Franklin
Episode: 1.05. Three Men and a Smoking Diaper
- "Blame the Condition"
Performed by: King Pleasure
Episode: 1.06. Madam I'm Adam
- "Monkey Man"
Performed by: Toots and the Maytals
Episode: 1.07. Planet of the Frohikes
- "Jailhouse Rock"
Performed by: Elvis Presley
Episode: 1.08. Maximum Byers
- "Hound Dog"
Performed by: Stephen Snedden (Jimmy)
Episode: 1.08. Maximum Byers
- "Frenzy"
Performed by: Misas Touch
Episode: 1.09. Diagnosis: Jimmy
- "Gypsy Tango"
Performed by: session musicians
Episode: 1.10. Tango De Los Pistolesros
- "Tango de la Pasion"
Performed by: session musicians
Episode: 1.10. Tango De Los Pistolesros
- "Tango Boca"
Performed by: session musicians
Episode: 1.10. Tango De Los Pistolesros
- "Tango Romantico"
Performed by: session musicians
Episode: 1.10. Tango De Los Pistolesros
- "Argentina"
Performed by: session musicians
Episode: 1.10. Tango De Los Pistolesros
- "Mystery Tango"
Performed by: session musicians
Episode: 1.10. Tango De Los Pistolesros
- "Tango Nervioso"
Performed by: session musicians
Episode: 1.10. Tango De Los Pistolesros
- "El Machista"
Performed by: session musicians
Episode: 1.10. Tango De Los Pistolesros
- "Neuvo Tango"
Performed by: session musicians
Episode: 1.10. Tango De Los Pistolesros
- "Tango a la Tuna"
Performed by: session musicians
Episode: 1.10. Tango De Los Pistolesros
- "Passionate Tango"
Performed by: session musicians
Episode: 1.10. Tango De Los Pistolesros
- "Rum and Coca Cola"
Performed by: The Andrew Sisters
Episode: 1.11. The Lying Game
- "Forever Young"
Performed by: The Band
Episode: 1.12. Cap 'n Toby
- "Weapon of Choice"
Performed by: Fatboy Slim
Episode: 1.13. The Truth About Yves