"I'm trying not to get to excited, but I’m convinced this is the best antioxidant I have seen yet," said Leslie Bouman, associate professor of dermatology at the University of Miami in the 2004 issue of allure magazine.
Virginia Beach, Va. - Describing idebenone as the "most potent" antioxidant he's researched to date, David H. McDaniel, M.D., believes the synthetic analog of ubiquinone (coenzyme Q10) represents the first of a new class of cosmeceuticals.
"I think we're at the dawning of pharmaceuticalization of skin care products," said Dr. McDaniel, pharmaceutical standards and testing to develop products that truly work.
He said clinical trials of idebenone prove it a powerful antioxidant that affects the appearance of skin in ways superior to products formulated with AHAs, vitamins C and E, and other antioxidants.
"Clinical studies thus far have shown that idebenone ... quenches inflammatory reactions and ... is a powerful antioxidant that destroys free radicals," he said. "The ideal anti-photo aging treatment is one that turns the right cellular reactions on and off in the collagen synthesis, and degradation and inflammatory pathways."
Why so much excitement about this powerful new antioxidant? Studies show idebenone not only shields skin from environmental damage, improves the appearance of fine lines and wrinkles, but reduces dryness and smoothes skin texture. Tests also prove this to be the most powerful and effective antioxidant known.
Based on
peptide technology MATRIXYL 3000 utilizes the two matrikines™ for their
synergistic effect in the neosynthesis of extracellular matrix molecules.
Clinical studies show that Matrixyl 3000 lifts and firms the skin, significantly
reducing the appearance of wrinkles. After only 2 months, the surface area of
the skin occupied by deep wrinkles was reduced by 45% on average.

Cucurbita pepo (Pumpkin), Aqua (Water), Glycolic Acid, Propylene Glycol, Salicylic Acid, Vaccinium myrtillus (Bilberry) Fruit extract, Saccharum officinarum (Sugar Cane) Extract, Acer saccharinum (Sugar Maple) Extract, Citrus aurantium dulcis (Orange) Fruit Extract, Citrus medica limonum (Lemon) Extract, Kosher Vegetable Glycerin, Matricaria chamomilla (Chamomile) Essential Oil, Cinnamomum cassia (Cinnamon) Bark, Zingiber officinale (Ginger) Root Powder, Pimenta officinalis (Allspice) Essential Oil, Myristica fragrans (Nutmeg) Powder, Pimenta officinalis (Allspice) Powder, Methyl/Propyl Parabens, EDTA
CAUTION: Should not be used by sensitive skin types. Discontinue use if irritation occurs. Apply vegetable oil to irritated area and consult a physician.