All India and AIIMS pre PG papers : Solved
Institute of Advance Medical Studies

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••••IMPORTANT•••• • DNA Replication is - RNA mediated • Starts with enzyme - Primase • Okazaki fragment is consist of 100 DNA and 10 RNA molecules. • Okazaki pieces are united by- DNA Ligase • Any Gap is filled by - DNA polymerase • Nicks are resealed by - DNA Topoisomerase (winding of DNA) • Un-winding of DNA Helix - DNA topoisomerase • Cleavage of DNA - Restriction Endonucleage • Cloning of large DNA Molecule - Cosmid Enzyme • Steriod are synthesized at - Smooth ER • PRotein - Rough ER • Nonsense codons are - UAG, UGA, UAA • Begins with - AUG (AUG codes for - methionine)

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CDSolved paper with references & explanatory answers
All India 2002 + AIIMS May 2002 + All India 2001 + AIIMS Nov 2001 + AIIMS May 2001 + Rajasthan2001
CDDescription of syndromes commonly asked in All India, AIIMS and other Pre-PG exams.
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CONTRAVERSY?
put up by Rohit Bhatnagar, Kolkata
Que. Which of the following is not a recognised causes of macrocytosis in the peripheral blood with normoblastic erythropoiesis in the bone marrow:
A. Cryptogenic cirrhosis
B. The administration of phenytoin
C. Chronic alcohol abuse
D. Hypothyroidism
Ans. B
A number of drugs antagonize folate by mechanisms which are poorly understood but are thought to involve an effect on absorption of the vitamin by the intestine. In this category are the anticonvulsants phenytoin (Dilantin) and primidone (Mysoline) and phenobarbital (Luminal). Megaloblastic anemia induced by these agents is mild.

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