Statistics on steroids
Then your body probably has less than 300 nanomoles of ARs, grand total, let's say. statistics on steroids Diabetes and steroids. Well, one 2. 5 mg tab of oxandrolone supplies about 8000 nanomoles of AAS. Clearly, that's far more molecules than your body has receptors. statistics on steroids Back muscles. A little math shows that all those receptors combined could bind only a small percentage of the molecules of AAS in one little 2. 5 mg tab. So binding to ARs cannot appreciably reduce the concentration of AAS in the blood. statistics on steroids Female muscle worship. Therefore, the ideas that ARs will bind most of whatever dose some author recommends, or that "spill-over" will occur beyond that, are entirely wrong. There just aren't that many receptors. Typical doses of AAS are high enough that a high percentage of the ARs are bound to AAS, whether the dose is say 400 mg/week or 1000 mg/week. If similar percentages of ARs are active - close to 100% in each case -- then why do higher doses give more results? It's a fact that they do, but there is not any large percentage of unoccupied receptors at the moderate dose. Thus, there is little room for improvement there. So at least part of the cause must be something other than simply occupying a higher percentage of receptors. And why did I pick those doses, rather than comparing normal levels with say 400 mg/ week?The fact that the ARs must form dimers to be active has an interesting consequence. The mathematics are such that if two ARs must join together to form an activated dimer, and both must bind a molecule of AAS, then the square must be taken of the percentage. This means that if say 71% of receptors are binding steroid, only 50% of the dimers will be activated. Thus, at low levels, there is more room for improvement than one would think. But if say 95% are occupied, then even after squaring that, there would still only be 10% room for improvement. But actual improvement - increase in effect - seems to be much more than 10%. Anabolism increases even as the dose becomes more than sufficient to ensure virtually complete binding. Why?One popular explanation is that high doses of AAS block cortisol receptors and are thus anti-catabolic. But if this were an adequate explanation, then one could use anti-cortisol drugs together with low doses of AAS and get the same results as with high doses of AAS. This isn't the case. In fact, if cortisol is suppressed, this simply results in painful joint problems. And if the cortisol-blocking theory were true, we also would expect that persons with abnormally low cortisol ought to be quite muscular.
Statistics on steroids
Info || Steroids-from-mexico || Anabolic diet results || Anabolic-androgenic-steroids