in Egyptian schizophrenic patients.
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| Regional cerebral blood flow in Egyptian schizophrenic patients. |
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| Thesis for MD Degree | |||||||||||||||||||||||||||
| Supervising Professors | |||||||||||||||||||||||||||
| Prof. Adel Sadek, MD, FRCPsych | |||||||||||||||||||||||||||
| Professor and Chairman of the Institute of Psychiatry -Faculty of Medicine ? AinShamsUniversity | |||||||||||||||||||||||||||
| Prof. MoustafaKamel , MD, FRCPsych | |||||||||||||||||||||||||||
| Professor of Psychiatry -Faculty of Medicine ? AinShamsUniversity | |||||||||||||||||||||||||||
| Prof. Ahmed Saad. MD | |||||||||||||||||||||||||||
| Ass. Professor of Psychiatry -Faculty of Medicine ? AinShamsUniversity | |||||||||||||||||||||||||||
| A.Prof. Abdel Nasser Omar MD, FAPA | |||||||||||||||||||||||||||
| Ass. Professor of Psychiatry -Faculty of Medicine ? AinShamsUniversity | |||||||||||||||||||||||||||
| Prof. Laila Faris Matta MD | |||||||||||||||||||||||||||
| Professor of Radiotherapy -Faculty of Medicine ? AinShamsUniversity | |||||||||||||||||||||||||||
| The purpose of the study was to compare regional cerebral blood flow (CBF) in drug-naive schizophrenic patients before and after atypical antipsychotic treatment. 20 schizophrenic patients (who were either drug naive and or drug free for at least 3 months) and 13 healthy volunteers were included in the study. Regional cerebral perfusion was studied with the use of a head-dedicated, high-resolution single photon emission computed tomography (SPECT) system. Cerebral SPECT scans were performed with technetium-99m-hexamethyl-propyleneamine oxime as a tracer. Regional CBF was measured as a ratio of regional tracer uptake to either cerebellar or whole brain tracer uptake before and after therapy and the results were compared. | |||||||||||||||||||||||||||
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