Understanding the Miracle
An Introduction to the Science of
Noni
The fruit of the Morinda Citrifolia plant, or "noni," has been known for thousands of years by tropical cultures and has recently been introduced to the general public as a dietary health supplement.  The claims that have been made about this fruit have been astounding, but little is known about these positive effects.  This booklet will attempt to explain what is in noni that is responsible for these positive effects and also how noni works to produce these effects.  We will also discuss some of the implications of this discovery.
Let us first sum up what happens to the noni juice as you drink it.  The primary important ingredient in noni is a large molecule called proxeronine.  When you drink a glass of Noni juice, the proxeronine goes through your digestive tract into the large intestine where it is then sent through the hepatic vein into the liver.  The liver is the main storehouse for many of the body's essential nutrients.  Every two hours the liver releases a certain amount of this proxeronine into the bloodstream, and then on to various tissues of the body.
After this release takes place we need to go down to the molecular level to understand what is happening.  If we look closely enough, we will see that proxeronine is a vary large molecule with a molecular weight of 17,000 atomic units.  (To understand exactly how big this is, a water molecule has a molecular weight of only 18).  It is a long chain with two club-like ends.  In order for the proxeronine to be made into xeronine it requires the help of a certain enzyme which is abundant in the body which has been named proxeroninase.  The process that changes proxeronine into xeronine is very complex, but to explain it simply, proxeronine wraps itself around proxeroninase and proxeroninase joins the two club-like ends of the proxeronine together and then cuts off the useless chain.  The remaining conjoined club-like parts combine with seratonin to make xeronine.
Once the xeronine is formed from proxeronine it now combines with proteins in your body in order to allow them to function.  In order to explain this part of the process more fully we need to understand a little bit more about proteins.
Proteins are perhaps the most important biochemical agents in your body.  Their name comes from the Greek proteios which means "prime'" or "chief" giving us a clue into their importance.  They are made up of long chains of amino acids. There are 20 amino acids that your body needs to make up your various proteins.  These amino acids combine together in specific sequences that are determined by your RNA.  It is the different sequence of amino acids in the protein that determines the protein's structure.  The chain winds around itself and clumps together to form a very large cluster of amino acids, or a protein.
Proteins have a variety of very important functions in the body.  First, they give structure to your hair, skin, and bones.  Proteins provide most of the structure of your body even down to the cell itself.  Second, they allow the transport of chemicals within and without the cell.  Proteins are interspersed throughout the cell membrane and they attract important nutrients and allow them passage through the membrane.  Third, proteins also act as hormones in the body.  Acting in this capacity, they are able to coordinate all body processes at the molecular level.  Fourth, they act as antibodies in their support of the immune system.  The antibodies attach to foreign bodily invaders (such as viruses) and incapacitate them so they can be disposed of.  Finally,  proteins act as enzymes in that they facilitate all chemical production in the body.  Your body is constantly breaking down and building chemical compounds and it is protein that allows this to happen.
Now that we have established the importance of proteins, we must understand that many of these proteins are not able to perform any of their duties without xeronine.  There is a specific site on certain proteins that allow them to combine with xeronine.  Not all proteins require xeronine to function, but many vital proteins acting as hormones, antibodies, and enzymes need xeronine.  The xeronine, now that it is joined to the protein, enables the protein to carry out its responsibility by translating energy that is derived from the water around it into useful chemical and electrical work.  This process deserves further explanation.
There is a tremendous amount of energy in water.  The water molecule is made of an Oxygen atom that is strongly joined to two Hydrogen atoms.  When several water molecules are put together (such as in a glass of water) the Oxygen from some water molecules will be attracted to the hydrogen atoms of the other water molecules.  This is what is known as Hydrogen bonding.  This Hydrogen bond (H-bond) is not quite as strong as the bond between the original Oxygen and Hydrogen in the molecule itself, but when you add up all of the Hydrogen bonds in a cup of water, it makes for a structure that is stronger than steel.  The truth is that not all of the Hydrogen and Oxygen atoms are H-bonded together.  It has been experimentally estimated that somewhere between 15-25% of the H-bonds are broken at any given time.  However, water has always been a mystery to scientists because the facts just don't add up.  On the one hand, if you just analyze water chemically, you will see that, with 20% of its H-bonds broken, it should have a stronger-than-steel structure.  But just looking at and observing water it is obvious that its structure is not as strong as steel, but is actually rather weak.  Here is the explanation:  if the H-bonds are broken at random throughout the liquid then its structure will remain strong, but if they are broken in line then it is possible for water to behave as a liquid.  If these H-bonds are constantly unzipping in line throughout the whole liquid then it will display aqueous properties and thus we will be able to reconcile the strength of the bonds within water to its visible properties.
We are now in a position to understand more about how xeronine gets the power to allow the protein to work.  Because of this constant unzipping of H-bonds, what we have is very strong "blocks" of water that are sliding past each other and pushing and pulling everything in its path.  Theoretically, it we could somehow direct this unzipping of H-bonds, we could direct where these water blocks are breaking apart.  This is exactly what xeronine does.  Its unique chemical structure allows it to send out a signal that will direct the breaking of the H-bonds in water.  By directing where these bonds are broken very rapidly, the xeronine is able to direct the movement of these powerful blocks of water.  As the blocks of water slide past each other they push and pull the protein that is sitting in the middle in a specific way.  This is a very powerful process that gives a tremendous amount of energy to the protein so it is able to do useful work.
This same process is happening in all forms of life.  Both plants and animals are manufacturing xeronine from proxeronine and using xeronine to enable their proteins in the same way that has been described that we as humans do it.  This means that all healthy tissues of plants and animals contain proxeronine.  We get our proxeronine supply through the food we eat.  If we already get proxeronine from the food we eat, you may ask, why do we need something like Noni juice to supplement the proxeronine that we are already getting in our food?  It is the answer to this question that will be addressed now.
It is true that you are getting a proxeronine supply through the food you eat.  Whether this is an adequate supply is a different story.  Along with all of the benefits of modern civilization, some unique problems have also been created.  With the dramatic increase in population in the 20th century, agriculture has changed drastically to meet the increasing demand.  With this increase in agricultural production, there has inevitably been an undue strain on the soil of many of these lands used for cultivation of food.  The chemical fertilizers that we have used to counteract this depletion of soil have been inadequate in supplying the food with micronutrients that are needed to ensure the health of the plant.  This depletion of soil and inadequate chemical fertilization that creates unhealthy crops naturally translates into the loss of many nutrients that are essential to us, including proxeronine.
In addition to soil depletion, a poor diet will also create a need for a supplement of proxeronine.  The fast-paced lifestyle of modern society has created a diet that is deficient in many important nutrients.  The average person today is not getting a well-balanced enough diet to supply him with all to the proxeronine he needs to function properly, thus creating a demand for a proxeronine supplement.  While it is best to get proxeronine from the food you eat, this is not always possible, so a proxeronine supplement becomes necessary.
Several other factors will also create an increased need for proxeronine in your diet.  Both sickness and a highly active lifestyle will place an increased demand on the proteins of your body.  In order for the proteins to work harder to keep up with these demands they will need an increased supply of xeronine.  To increase the supply of xeronine in the body,  more proxeronine will need to be supplied through your diet.  Also, in old age our bodies become less efficient and require more nutrients to sustain health. Among these nutrients is proxeronine.
All of the situations listed above will create a need in the body for more proxeronine than you are getting normally.   If this need is not satisfied, the proteins in your body are not able to cope with the demand that is placed on them; when this occurs, sickness and fatigue result, and eventually even death.  It is entirely possible that many of our modern diseases are caused by a lack of xeronine in the body.  If this is the case, then increasing proxeronine intake will counteract and "cure" these diseases.  This is what is responsible for the many testimonials of Noni juice.  When someone has a low level of xeronine in his body, he will feel the negative effects of the inability of his proteins to function.  When he then increases his intake of proxeronine by drinking Noni juice and restores the xeronine in his body to a healthy level,  he will overcome the effects of this illness and experience seemingly "miraculous" results.  The reason so many  people acclaim the "miracle" of Noni juice, and report so many amazing results from taking it is due to the fact that Noni juice is supplying a vital nutrient?proxeronine?that is, in some cases, drastically missing from their diet.
This is why Noni juice is such a uniquely good health product.  Rather than supplying the body with an active chemical like so many drugs and pharmaceuticals do, Noni juice supplies the body with the precursor to the active chemical, thereby allowing the body to take control of itself.  Noni juice supplies the body with proxeronine, and the body regulates this supply and uses what it needs to maintain a healthy level of xeronine.  What is not used is simply discarded.  Therefore, it is not possible to overdose on the proxeronine in Noni juice.
Now that we understand the vital role that xeronine plays in the body, let us explore a couple of scientific mysteries that are explained with our newly acquired knowledge of xeronine.
As mentioned before, both plants and animals use xeronine.  An interesting difference, however, between plants and animals is in the way in which they dispose of xeronine when it is no longer needed.  Once xeronine has executed its duty, it becomes necessary for the organism to rid itself of the used-up xeronine so that it does not continue to act where it is not needed.  If we had an excess of xeronine, causing our proteins to do more work than we wanted them to do, it would create problems.  The solution to this is already built in to nature.  Xeronine is a very unstable chemical compound. When left on its own it will break down and become useless.  Most forms of life will allow the xeronine to just naturally break down.
However, with many plants it is a different story.  While most forms of life (ourselves included) merely allow xeronine to break down after its job has been performed, many plants desire to keep the xeronine so that it can be stored for the precious nitrogen that it contains.  In order to keep it for storage, but also to inactivate it, the plant will add strings and clumps of "molecular garbage" to it so that it will not break down, but also will not combine with protein anymore.  Once the molecular garbage has been added to the xeronine it becomes a very well-known chemical compound called an alkaloid.
Alkaloids were one of the first biochemical compounds that were discovered.  There are now over 10,000 known alkaloids that have been found in various plants.  Some of these alkaloids include nicotine, cocaine, heroin, and morphine.  Until now science has not been able to adequately explain why plants contain alkaloids and what they do in the plant.  With an understanding of xeronine, however, we now see that these alkaloids are nothing but "junk" forms of xeronine, designed to stabilize the xeronine so it can be kept for its nitrogen supply.
This is fine for the plant in which these alkaloids are manufactured, but interesting problems are encountered when we introduce these alkaloids into our bodies.  These alkaloids are completely inactive in the plant, but, because they are unfamiliar to us and resemble xeronine in structure, they are treated and accepted as xeronine by our proteins.  For example, when you smoke a cigarette, you release a great supply of free nicotine into the body.  Though the nicotine is inactive in the tobacco plant, it resembles the structure of xeronine enough that it fools the proteins in  your body into accepting it rather than the xeronine that it naturally wants.  Once the nicotine is accepted into xeronine's rightful place on the protein, albeit awkwardly, it activates the protein in the same way that xeronine would, only in a less-effective way.  Because it still has the same basic structure as xeronine it is still able to activate the protein, but it doesn't do as well because of the molecular junk that serves to inhibit it.
If you continue to smoke cigarettes and take nicotine into your body, eventually your body will adapt to the nicotine by slightly changing the shape of the protein so it will fit with nicotine rather than xeronine.  This is the molecular basis for addiction.  You crave cigarette after cigarette because many proteins in your body literally need the nicotine molecules to function, just like the protein once needed the xeronine molecule.  The more you smoke the more proteins will be converted to nicotine-proteins from xeronine-proteins and it will become increasingly difficult to quit.  When you decide to quit smoking, it is very difficult and painful because many proteins in your body are now made unable to function because of the lack of nicotine.  This is why you feel withdrawal pains.  Eventually, however, if you keep the nicotine out of your system, your proteins will again adapt to the xeronine that is already present in the body and you will return to normal, no longer physically craving  nicotine.
This same process applies to all foreign alkaloids that we take into our bodies including caffeine, cocaine, heroin, morphine, and so forth.  When we take in these foreign alkaloids our proteins adapt to them and we change from our natural need of xeronine to an unnatural need of foreign alkaloids.
The reason we get a "high" from taking in these alkaloids is simple.  Because they resemble xeronine just enough to fool us, these foreign alkaloids still allow proteins to perform work.  If we flood our bodies with these foreign alkaloids (by taking a drug) they will cause our proteins to act more than normal thus creating a feeling of euphoria.  Different drugs will behave differently because of the different pieces of molecular junk that are added to them.  Cocaine will act differently in the body than morphine because of the slight difference in structure between the two that will limit or enhance certain aspects of xeronine's natural function.  The key is that they are all simply mimicking xeronine's natural function.  Many alkaloids are commonly used as drugs in the pharmaceutical industry, but underlying all of the pharmacological activity of these foreign alkaloids is the natural function of xeronine.
Once we understand the true nature of these alkaloids and the process in which we become addicted to them, we can more fully help people overcome their drug addictions.  You may ask the question, why is it so easy to become addicted to something, and yet so hard to break the addiction?  The answer is simple once we understand the true nature of addiction.  When you first take a drug like heroin, for example, you are literally flooding the body with this foreign alkaloid.  This great supply of heroin in the bloodstream overcomes the smaller supply of natural xeronine and converts many proteins quickly.
To overcome this difficulty and literally "cure" your addiction, all you need to do is flood your body with xeronine, just like you originally flooded your body with the foreign alkaloid.  By doing this you "re-addict" yourself to xeronine and you can avoid all to the problems of withdrawal.  According to this theory, it would be possible to overcome a drug addiction just as quickly as the addiction was created (possibly even 1-3 days) without any problems of withdrawal?if treated correctly.  To treat for addictions in this way with proxeronine, you need to somehow get the proxeronine into the bloodstream rather than through the digestive tract.  In order to accomplish this, one possibility is to place a few drops of a proxeronine supply (Noni juice) under the tongue with an eyedropper every hour.  Doing this will release the proxeronine straight into the bloodstream from the soft tissue under the tongue rather than through the digestive system where its release is strictly regulated by the liver.
As well as acting as a cure for addiction, our knowledge of xeronine's role in the body will also lead us to many other applications.  One of these applications for Noni juice is its potential in cosmetic products.  As explained before, the liver is the main place of storage for proxeronine.  The second major storage place for proxeronine is the skin.  Proxeronine is converted to xeronine all over the body, and the skin is no exception.  In order to keep your skin healthy and smooth, it will need to contain an ample amount of proxeronine.  Lack of proxeronine in the skin may be responsible for unhealthy skin and many other skin conditions.  Proxeronine is also needed to maintain healthy hair and scalp.  Addition of proxeronine to the scalp and hair will leave a marked improvement if those areas are lacking.
Another very exciting application for xeronine is as a pain-reliever and an anaesthetic.  Currently the most powerful pain-relieving drugs are foreign alkaloids like morphine and codeine.  We learned earlier that foreign alkaloids are nothing but counterfeits of xeronine made for storage by plants.  Therefore, anything that these foreign alkaloids can do, xeronine can do better and more naturally.  Xeronine acts as the body's supreme painkiller because it works with endorphins in the body to numb pain and produce feelings of euphoria.
Endorphins are the hormones that are responsible for producing good feelings in the body.  They bind to certain proteins just like the xeronine does.  When xeronine and an endorphin are bound to a protein, the xeronine channels the energy from water into the endorphin and the endorphin creates a good feeling within you.  Science is still working on how the endorphin creates these good feelings, but we know that they are somehow responsible.  However, without the xeronine, the endorphin is useless.
As well as its pain-relieving properties, xeronine also works to stimulate the body.  Xeronine's simulative activities are mirrored through the activity of its counterfeit foreign alkaloid cousin, caffeine.  When you drink a cup of coffee in the morning, caffeine floods your body.  These caffeine molecules add to the proteins in your body, taking the place of xeronine, and enable them to work.  Because you are adding many caffeine molecules from one cup of coffee, your proteins are able to work much harder than usual.
The effects you would feel from a significant quantity of pure xeronine introduced into the body would be very similar to the effects you feel from caffeine.  This stimulating effect of xeronine could have amazing potential.  It could significantly improve athletic performance as well as increasing your ability to concentrate and think clearly.
We have listed only a couple applications of the exhaustive list that could be created for the tremendous potential that a proxeronine and xeronine supplement would have.  Consumers of Noni juice have already experienced the amazing boost that a proxeronine supplement can have on the immune system and many other areas of the body.  The only limit to the further potential of xeronine and proxeronine is our imagination.
This information is available in booklet form entitled Understanding the Miracle. It is the result of a series of interviews conducted by A.K. Olsen with Dr. Ralph Heinicke, from June of 1998 to August of 1998, and is available from Direct Source.
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