Epinephrine
Adrenergic catecholamine, beta 1 and 2 agonist causing increased levels of cAMP which causes bronchodilation, cardiac and CNS stimulation.  Large doses cause vasoconstriction while small doses can cause vasodilation via beta-2 mediated action on vascular receptors.
Indications:
Many in EMS settings.  Anaphylaxis, severe asthma/RAD, pulseless electrical activity (PEA), asystole, ventricular fibrillation/pulseless ventricular tachycardia, symptomatic bradycardia, newborn resuscitation,
Common Side Effects: 
Tremors, anxiety, dizziness, palpitations, dysrhythmias, anorexia, nausea, vomiting, dyspnea.
Potentially Lethal Side Effects:
Cerebral hemmorhage.
Contraindications:
Hypersensitivity to sympathomimetics, narrow angle glaucoma, nonanaphylactic shock during general anesthesia, labor, cardiac dilation, conornary insufficiency, cerebral arteriosclerosis, organic heart disease.
Adult dosing:
Allergic reaction/Anaphylaxis/Asthma/RAD
SQ/IM:  0.3mg of 1:1000 for moderate-severe condition q 10-20 min, prn

PEA/Asystole/VFib/PVT
IV Push:  1mg of 1:10,000 q 3-5 min
Pediatric dosing*:
Symptomatic Bradycardia
IV/IO bolus 0.01mg/kg of 1:10,000
ETT bolus 0.1mg/kg of 1:1,000


Allergic reaction/Anaphylaxis/Asthma/RAD
SQ/IM:  0.01mg/kg of 1:1,000 to Max 0.3mg q 10-20 min, as indicated.

PEA/Asystole/VFib/PVT
IV/IO bolus 0.01mg/kg of 1:10,000
ETT bolus 0.1mg/kg of 1:1,000
 
Infusion follows recovery of perfusing rhythm: 
   Begin at 0.1mcg/kg/min, adjust to effect, or Max 1mcg/kg/min

Notes:
-  Use with caution in patients with suspected myocardial ischemia.

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