Diabetic emergency of hypoglycemia, defined as blood glucose level of <60, with signs and/or symptoms or any degree of altered mentation.
Hyperglycemia, Delerium Tremens, cranial/spinal hemorrhage, CHF.
Potentially Lethal Side Effects:
Loss of consciousness, CHF, pulmonary edema
D50: Slow IV: <25g q 10-20 min, per indication
<1 mo: D10: Slow IV/IO: 2ml/kg*
1mo-Child: D25: Slow IV/IO: 2ml/kg*
Children >8-10 y/o receive adult dosing.
Assume stock supply of 50 ml D50, prefill.
Preparation of 5% solution:
Mix 5ml of 50% solution with 45ml NaCl, yeilding 2.5g/50cc (used as base for
Magnesium Sulfate in Torsades)
Preparation of 10% solution:
Mix 10ml of 50% solution with 40ml NaCl, yeilding 5g/50cc
Preparation of 25% solution:
Mix 25ml of a 50% solution with 25cc NaCl, yeilding 12.5g/50cc
Dextrose has a low pH, and is necrotic to extravascular tissue. Therefore, it should not be administered distal to vasculature (venous) that has been punctured, or otherwise traumatized. Administration should be stopped and relocated if any sign/symptom of extravasation occurs (i.e. pain/swelling at access site).