| Aspirin | |||||||||||
| Salicylate non-narcotic analgesic, NSAID, antipyretic, antiplatelet which blocks pain impulses in CNS. Inhibits prostaglandin synthesis. Antipyretic action results from vasodilation of peripheral vasculature. Decreases platelet aggregation by mechanism of near-total, rapid inhibition of thromboxane A2 production. | |||||||||||
| Indications: In the emergency setting, chest pain suggestive of acute coronary syndrome or acute myocardial infarction. |
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| Contraindications: Child <12 y/o, children with flu-like Sx, known hypersesnsitivity. Pregnancy D. Relative only: Asthma, peptic ulcer. |
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| Common Side Effects: Nausea, vomiting, rash Potentially Lethal Side Effects: Thrombocytopenia, agranulocytosis, leukopenia, neutropenia, hemolytic anemia, convulsions, coma, GI bleeding, hepatitis. |
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| Adult dosing: Chest pain indicative of ischemia PO/BUC: 324mg, chewed and dissolved in mouth. |
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| Pediatric dosing*: Not routinely administered to children in prehospital setting |
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| Notes: |
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