| Albuterol | |||||||||||||
| Adrenergic beta-2 agonist, sypathomimetic, bronchodilator by action on pulmonary B-2 receptors by increasing levels of cAMP, relaxing smooth muscle in effect. Produces bronchodilation. Stimulates cardiac, CNS, diuresis, gastric acid secretion. It is longer-acting than isoproterenol. Also causes intracellular shift of potassium. | |||||||||||||
| Indications: CHF/pulmonary edema, acute asthma, allergic reaction/anaphylaxis, general medical management of patients with wheezing/rales/ronchi/diminished or absent lung sounds secondary to inhalation burns/URTI/Bronchitis/pneumonia/Reactive Airway Disease (RAD), Presumed Hyperkalemic Cardiac Arrest, |
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| Common Side Effects: Tremors, anxiety, restlessness, Potentially Lethal Side Effects: Bronchospasm |
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| Contraindications: Hypersensitivity to sympathomimetics, tachydysrhythmias, severe cardiac disease, heart block. |
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| Adult dosing*: CHF, RAD, Allergic reaction/Anaphylaxis, General medical management, Burns Neb: 2.5mg (1 unit dose) continuous, titrated to clear lung sounds. Presumed hyperkalemic cardiac arrest ETT: 10mg (4 unit doses) directly instilled to tube, follow with 10ml flush of NaCl or Sterile water. |
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| Pediatric dosing*: RAD, Allergic reaction/Anaphylaxis, General medical management, Burns Neb: 2.5mg (1 unit dose) continuous, titrated to clear lung sounds. |
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| Notes: * Dosing and protocols vary among providers. Check local protocols for specifics. - Albuterol has toxic interaction with Theophylline. - Use with oxytoxics may induce severe hypotension - May cause ECG changes and hypokalemia when administered with diuretics. - The following drugs cause increased effect of Albuterol: MAOIs, TCAs, other adrenergics. - Beta blockers may inhibit the effect of Albuterol. ** Some protocols call for addition of Atrovent to nebulized Albuterol treatments. Check local protocols for specifics. |
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