HIV post exposure risk score

HIV post exposure risk score(B score), updated October 2005

Exposure score
Score = 1 Mucous membrane & non intact skin exposure: small volume e.g. few drops
Score = 2 Mucous membrane & non intact skin exposure: large volume e.g. major blood splash or Percutaneous injury: less severe e.g. solid needle, superficial injury
Score = 3 Percutaneous injury: more severe e.g. hollow needle, deep puncture, visible blood on device or needle used in patient�s vessel

Source score
Score = 1 Unknown status and has HIV risk factor
Score = 2 HIV positive class 1 : asymptomatic HIV infection or viral load < 1,500 copies/ml
Score = 3 HIV positive class 2 : symptomatic HIV infection, AIDS, acute seroconversion or high viral load

B score = Exposure score + Source score
Score < 3 low risk: do not need post-exposure prophylaxis
Score 3 - 4 moderate risk: need basic regimen for 4 weeks
Score > 4 high risk: need expanded regimen for 4 weeks

Basic regimenis Zidovudine(ZDV) 200mg po tid plus Lamivudine(3TC) 150 mg po bid or Lamivudine plus stavudine

Expanded regimen is basic regimen plus Efavirenz or Lopinavir/ritonavir(prefered)

Following situations do not need post-exposure prophylaxis
- Intact skin exposure
- Source status: Anti-HIV negative
- Source unknown status but no HIV risk factor

Hosted by www.Geocities.ws