J. C. Prolla - Cytopathology Case 09A 2006 Adenoid cystic carcinoma

Drs. Prolla and Diehl's Case of the month ~ September 2006

Adenoid cystic carcinoma: FNA Left parotid mass, 62-year old male

Adenoid cystic carcinoma 200x M-G-G staining, shows several spherical structures, small basaloid epithelial cells, surrounding hyaline material, basement membrane material.

Adenoid cystic carcinoma 500x M-G-G staining, detail view shows the spherical structures, small basaloid epithelial cells, surrounding faintly eosinophilic hyaline material

adenoid cystic carcinoma 200x M-G-G staining, low power view shows the perfectly spherical structures: small basaloid epithelial cells, surrounding the faintly eosinophilic hyaline material

Adenoid cystic carcinoma 500x M-G-G staining, high power view shows the perfectly spherical structures: small basaloid epithelial cells, surrounding the faintly eosinophilic hyaline material

Adenoid cystic carcinoma: cytologically, it has a characteristic cellular population: small basaloid epithelial cells (with high nuclear/cytoplasmic ratio) surrounding nearly spherical cystic areas, filled with basement membrane hyaline material. In the differential dignosis one should consider the so-called basal cel adenomas. In this latter tumor, the basement membrane material is much scarce.

Histology in our case showed the characteristic cribriform pattern, with the cystic spaces filled with hyaline homogeneous material.

Case September 2006 References List of cases Atlas

Hosted by www.Geocities.ws