HPV lesion ~ nuclear and cytoplasmic changes are consistent with LSIL. Koilocytes: note that in addition to perinuclear cavitation ( with well defined borders), nuclear abnormalities as seen here are required to make an interpretation of LSIL. "Parakeratosis" is a descriptive term used for abnormal keratinization of the cytoplasm. Very large cells with multinucleation are frequent in LSIL. |
References | List of cases | Atlas |