Prostatic FNA by transrectal approach. Smears with abundant cellularity; many disperse isolated malignant cells, some quite large, with nuclear hyperchromasia and large nucleoli. Many small and medium sized cell clusters, with scanty cytoplasm. Nuclei with irregular, coarse, and irregularly clumped chromatin.
The use of FNA in the evaluation of prostatic nodules has been largely abandoned by most urologists, that favor large bore trucut needles, and do transrectal or transperineal biopsies. I think the FNA transrectal approach is easier, more economical, and with much less trauma.