nThe cause of fibromyalgia is
unknown. However, there are several hypothesis about its cause:
nGenetics – reported 73% of close relatives have fibromyalgia or exhibited clinical evidence of abnormal muscles.
nMuscular – studies have shown reduced levels of ATP, phosphocreatine, and ragged red fibers.
nNon-restorative sleep – due to findings of abnormal EEG patterns (fast alpha wave superimposed on a slower delta
wave)
nNeuroendocrine – b/c of findings of lower free-cortisol levels, low CSF serotonin, and high CSF substance P levels.
nSource:
Koopman: Arthritis & Allied Conditions, 1623-1625.