QCPU's main campus is at along Quirino High-way, Barangay San Bartolome, Novaliches, Quezon City. It is a 4.42-hectare compound that also houses the Korea-Philippines Information Technology Center (KorPhil) whose advanced IT training facilities have also been made available to the university. The university also operates an Enterprise Development Center, from its main campus, designed to connect its Entrepreneurship course with the needs of small and medium-scale businesses in the city.