MALE SEX HORMONES

ANDROGENS

Produced in testes, adrenals, and ovaries

Regulated by LH

Promotes growth

Regulates reproductive organs

Spermatogenesis

Closes epiphyseal plate

ANDROGENS - ANABOLIC PROPERTIES

Increase muscle mass

THERAPEUTIC USE

Hypogonadism

Promote anabolism in chronic debilitating diseases

Treatment of Anemia

Treatment of estrogen induced cancers

Side Effects

Female masculazation - baldness, atrophy of sex organs

Decrease growth in children

Sodium and Water Retention

OTHER CONCERNS

Hepatic Cancer

Hypercalcemia

CONTRAINDICATIONS

Cancers stimulated by androgens

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