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Abstract |
Same
Hematological
treated
with some hypoglycemic plants
*Zoology
Department. Faculty of science ,Al -Azhar, University.
**Oral Medicine, Periodontology ,Oral Diagnosis and Radiology department, Faculty of Dental Medicine (girls section) Al- Azhar, University.
The present study was designed to evaluate the effect of some
antidiabetic plants on the hematological parameters in aloxan induced diabetes
in albino rats.
Eighty
adult albino rats (120-±20 gm b.wt) were randomly divided into eight groups ten
on each group, the first group conserved as control group. The remaining rats
were injected with alloxan to induce diabetes. The second group conserved as
diabetic group. The third group was diabetic rats treated with a mixture consists
of Nigella Sativa, Aloe Vera, Ferula
assa-foetida , Boswelli
Carteri, Commiphora
Myrrha. (0.1ml/100gm
b.wt),
Fourth group treated with 0.1ml/100gm
b.w of Nigella Sativa, Fifth group treated with 0.05ml/100gm b.w of
Aloe Vera,Sixth group treated with
0.1ml/100gm b.w of Ferula
assa-foetida, Seventh
group treated with 0.1ml/100gm b.w of
Boswelli
Carteri, Eighth group
treated with 0.1ml/100gm
b.w of Commiphora Myrrha.
Haematological parameters includes: red blood cell count (RBCs), hemoglobin
concentration (Hb), hematocrit value (Hct%), total and differential white blood
cell cont (WBCs) were done after 30 days of treatment and after 15 days of
recovery period.
The result of RBCs
count, Hb concentration and Hct value were
significantly decreased in diabetic,
Nigella Sativa and
Aloe Vera treated groups, throughout the
experiment, except Aloe Vera treated
group showed insignificant change after the recovery period.while insignificant
changes was recorded in the remnant groups during the experimental period.
WBCs count, lymphocyte and
neutrophil percentage were highly significant increased in diabetic and Ferula
assa-foetida treated rats after treatment and recovery periods. While
insignificant differences were observed in the other treated groups. Moreover,
no significant changes were recorded in eosinophils and monocytes in all groups
throughout the study period.
Diabetes mellitus in experimental animal can be
treated with some plants which have antidiabetic effect, the present
investigation was designed to illustrate any hazard effect of these plants on
some hematological parameter. Further investigations on each plant and their
mixture are needed to role out its effect on both diabetes and the vital
parameters.
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