M.Pharm Project Work at LM College of Pharmacy, Gujarat University (1993-1995)
Title: Formulation design and pharmacometric evaluation of sustained release alginate microspheres containing theophylline.
Summary: The microspheres of theophylline were prepared by ionotropic gelation to study the influence of formulation and process variables on t90. The pharmacokinetic parameters, for dogs, were determined using
non-linear regression analysis. The publications
and presentations
related to invitro-invivo correlation (IVIVC) are:
- Gohel, M.C., Jani, G.K., Amin, A.F., Patel, K.V. and Gupta, S.V. (1997) Application of classical experimental design for the development of theophylline microspheres.
J. Contrl. Rel. 45,
265-271.
- 46th Indian Pharmaceutical Congress, Punjab University, Chandigarh, India 28-30 December 1994. (POSTER PRESENTATION
– Gohel, M.C., Amin, A.F. and Gupta, S.*
Studies in preparation and characterization of calcium alginate microspheres using theophylline as a model drug.)
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