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OUTILS DE TRADUCTION Dans les actualites h DATE DESCRIPTION SOURCE April 28, 2005 Europe Drafts New Law to Prevent Bird Flu Epidemics BRUSSELS, Belgium, April 28, 2005 (ENS) - Europe will soon have a new law to control bird flu viruses that do not cause serious disease to keep them from mutating into viruses that do. The highly pathogenic virus forms have caused the most dramatic epidemics among birds and are most likely to harm human health. ENS April 28, 2005 We need luck to avoid flu pandemic This is not to frighten you, but to take a sober look at a health crisis that could soon be at our doorsteps. We have been getting fragments of it from inside-page newspaper stories and an occasional broadcast report. TED VAN DYK SEATTLE POST-INTELLIGENCER COLUMNIST April 28, 2005 Swiss get ready for human flu pandemic Swiss react to bird flu pandemic warning Switzerland arms itself against bird flu SWISSINFO April 2005 Preparing for the flu Willemien Groot Radio Netherlands April 25, 2005 Killer flu mysteries Among influenza researchers, the well-worn question is not 'if' but 'when' a flu pandemic will happen. With bird flu ongoing in Asia, scientists from around the world are racing to answer a host of unanswered questions about the influenza virus. Madeleine Amberger and Laura Durnford Autio Radio Netherlands April 26, 2005 Flu Prevention WITH IMPRESSIVE patience, the World Health Organization is carefully following the progress of H5N1 avian flu, the virus that has now killed more than 50 people in Asia. Scientists tracking the virus have recently observed that fewer people who contract the disease die immediately. They've also found that some who test positive for the virus show no symptoms. Paradoxically, these changes could mean the disease has become more dangerous: The virus may be mutating, acquiring characteristics that help it spread faster. Washington Post Avril 14, 2005 Alerte à la grippe asiatique Des échantillons d'un virus mortel ont été envoyés par erreur dans des laboratoires à travers le monde Des échantillons du virus de la grippe asiatique, qui fut à l'origine d'une pandémie en 1957-58, ont été envoyés par inadvertance à des milliers de laboratoires dans le monde, dont une vingtaine au Canada. L'Organisation mondiale de la santé (OMS) a appelé hier tous ces laboratoires à détruire immédiatement ces souches potentiellement mortelles et ayant le pouvoir de provoquer une épidémie mondiale. Un tel scénario demeure toutefois peu probable, ont affirmé hier les autorités sanitaires nationales et internationales. Pauline Gravel Le Devoir QUEBEC April 17, 2005 Bird flu epidemic fears fading THE first clue that something terrible was happening around the rice fields of the Red River delta came when Ngo Le Hung, a 31-year-old teacher, suddenly died, gasping for breath, a few days after his wedding. Michael Sheridan Thai Binh Vietnam The Sunday Times April 15, 2005 Bird-flu threat: Think globally, prepare locally These hens have been raised at Wilcox Farms near Moses Lake since they were a day old. When you enter Wilcox Farms' egg-production facility in Central Washington, you might think you've arrived at a sterile, classified defense laboratory. Warren King Seattle Times medical reporter April 16,2005 Bird flu outbreak leads to fears of pandemic The threat of a killer flu pandemic is greater than ever because of the spread of the bird flu virus in south-east Asia, the World Health Organisation said yesterday. Sebastien Berger in Hanoi Roger Highfield, Science Editor News Telegraph April 15, 2005 Bird flu seen as Ulster's top health threat Special teams set up to deal with possible pandemic Ulster health chiefs are treating the bird flu pandemic as the "number one public health threat of the moment," it emerged today. Special teams consisting of health care officials all over the province, have already been set up to deal with any eventual problem. Nigel Gould Belfast Telegraph April 14, 2005 Bacterial pneumonia killed 14-year-old boy Exposure is common, county officials said, but it is rare for a patient to die. The schools are safe, parents were told. The illness that killed a Florence Township seventh grader Friday is no longer a mystery. Jennifer Moroz Inquirer Staff Writer Broadcast: 14/04/2005 Virus has potential to ignite global emergency: WHO Australian Broadcasting Corporation TV PROGRAM TRANSCRIPT April 13, 2005 Nobel scientist warns on bird flu Avian flu - caught directly from birds, and which kills in seven cases out of 10 - could suddenly sweep through the human population, killing 70 million people according to World Health Organisation estimates, a Nobel laureate warned yesterday. Peter Doherty, of the University of Melbourne, who shared the 1996 Nobel prize for medicine, was speaking at an assembly of laureates in Lyon, France, 50 years to the day after the first announcement of an effective vaccine against the crippling disease poliomyelitis. World health teams hope to eliminate polio altogether by the end of 2005. But, Prof Doherty warned the Biovision conference, there were more immediate hazards. Tim Radford in Lyon The Guardian April 13, 2005 Journal calls for attempt to stop a flu pandemic; WHO studying feasibility "Ideally Western governments should come together and say: 'Here's the money or here's the drugs and let's send them to where they're needed,' " Dr. John Hoey, editor of the Canadian Medical Association Journal, said in an interview Monday. Helen Branswell Canadian Press Canada.com April 13, 2005 EU mulls bird flu pandemic fund STRASBOURG, France (Reuters) - The European Union should be able to dip into a 1 billion euro (680,000 million pound) disaster fundto buy emergency vaccines and anti-viral drugs if there were bird flu pandemic, the EU executive Commission says. SwissInfo April 13, 2005 Bird Flu Widespread in Mekong Delta -More Than 70% of Duck, Geese Test Positive for Bird Flu in Vietnam's Mekong Delta In the US, the 1918 Spanish Flu killed 500,000, the 1957 Asian Flu killed over 68,000, and the 1968 Hong Kong Flu killed over 33,000. Scientists agree conditions are ripe for another pandemic, and they're working feverishly to prevent this from happening. HANOI, Vietnam — More than 70 percent of random duck and geese samples have tested positive for bird flu in Vietnam's southern Mekong Delta, but many farmers have refused to slaughter their flocks, officials said Wednesday. ABC NEWS April 13, 2005 Marburg still peaking - WHO Uige - There is no end in sight to the outbreak of the Marburg virus in Angola, a top expert from the World Health Organisation said on Wednesday, citing "massive problems" in mobilising Angolans to fight the Ebola-like bug in this northern city. News24.com April 12, 2005 New Analysis Finds Worrisome Gaps In U.S. Planning for An Avian Flu Outbreak Says Trust for America's Health Trust for America's Health (TFAH) today released a review of U.S. pandemic flu plans that found many planning topics remain under- addressed and additional actions could be taken to improve preparations and reduce the risks posed by an outbreak. Some key areas of concern include vaccine and treatment shortfalls, gaps in containment strategies, limited plans for how to keep the public informed, and inadequate review of state plans for quality and feasibility. Laura Segal 202-223-9870 ext. 278 Michael Earls 202-223-9870 ext. 273 Trust for America's Health April 12, 2005 The curse of the Marburg There are fears that the Marburg haemorrhagic fever diagnosed in Angola could reach South African shores. As with most highly contagious diseases there is a danger of widespread panic as well as incorrect information being circulated. The Editor The Star April 11, 2005 SARS report raises serious questions about province's emergency bill TORONTO (CP) - Emergency powers devised in the wake of the SARS crisis need to be overhauled because they give Ontario government officials too much "unrestricted" power to override current laws and could face a legal challenge if used, says an interim report by Justice Archie Campbell released Monday. Gillian Livingston Canadian Press April 11, 2005 Bird flu: Quack alert Phnom Penh - Cambodia's latest bird flu death may have been caused by contact with ducks carrying the deadly H5N1 virus, a World Health Organisation official said on Monday as a public awareness campaign geared up. News 24 . COM April 11, 2005 Speedy Marburg Disease Diagnosis Vital - UN UN Stresses Speedy Diagnosis In Fighting Deadly Marburg Disease In Angola With the toll from the largest, deadliest and most intense outbreak of Marburg fever on record steadily climbing in Angola, the United Nations health agency is focusing on the need for exceptionally precise diagnostic steps to prevent the spread of the rare but highly lethal haemorrhagic disease further afield, or even to another country. Press Release: United Nations April 10, 2005 Hunting a killer virus As more Angolans die from an Ebola-type virus, Fred Bridgland in Johannesburg talks to one of the scientists who risk everything to seek the origins of this horrific and terrifying disease Sunday Herald April 10, 2005 WHO halts Angolan Marburg work, locals attack medical teams LUANDA: Volunteers working amid the Marburg-affected population in the Angolan district of Uige were attacked by local residents over fears that they (the volunteers) could be spreading the deadly infection. WHO said it has to halt the medical relief work as a result of violent attacks. Alan Cross Earth Times April 10, 2005 Experts Use SARS Lessons for Bird Flu Preparedness BANGKOK, As public health experts lay the groundwork to combat a possible pandemic triggered by the lethal bird flu virus in Asia, they have an equally lethal infection that struck two years ago - SARS -- to thank for the current state of readiness. Marwaan Macan-Markar IPS April 10, 2005 Medics attacked as deadly virus spreads THE World Health Organisation (WHO) has halted a campaign in western Angola against an outbreak of Marburg virus after residents attacked its teams in apparent fear they could be spreading the deadly infection. Zoe Einstein in Luanda Reuters April 10, 2005 Recent outbreak of bird flu could devastate N. Korea SEOUL, SOUTH KOREA -- In recent years, North Korea's Kim Jong Il ordered his army to build chicken farms to fight the country's chronic food shortage and to sell abroad for hard currency. Just this month, North Korean-raised chickens were due to be exported for the first time, to neighboring South Korea. Barbara Demick Los Angeles Times Avril 8, 2005 La République Démocratique de la Corée du Nord a officiellement demandé l'aide de la communauté internationale pour la lutte contre l'Influenza Aviaire (IA), ont déclaré aujourd'hui l'Organisation Mondiale de la Santé Animale (OIE) et l'Organisation des Nations Unies pour l'Alimentation et l'Agriculture (FAO). OIE April 8, 2005 Marburg red alert for SA Port Elizabeth - New fears were expressed on Thursday that the Marburg virus had reached South African soil when a child in Morningside Clinic in Johannesburg showed symptoms of the infection. Carien du Plessis NEWS 24 .com April 8, 2005 Bird flu outbreak a reality The bird flu outbreak that has recently killed 50 people in Asia and cost the region billions of dollars could spread to other parts of the world, reported the global animal health body OIE. "The potential for the disease to spread to other continents is real and the international scientific community cannot remain insensitive to the challenge of preventing this happening," OIE Director-General Bernard Vallat told a conference in Paris. TVnz.co.nz April 7, 2005 Marburg's behaviour bewilders scientists Rising death toll flags unexplained character of killer virus. The Marburg virus has infected mostly children in this outbreak. The current outbreak of the deadly Marburg virus in Angola is raising difficult questions about this enigmatic pathogen and its origins. Helen Pearson NATURE April 7, 2005 Preparing Against Pandemic Influenza, Speech by US Health Secretary, Mike Leavitt This is a speech by Mike Leavitt, US Health Secretary, at the The National Academy of Sciences. Thank you, Harvey, for that kind introduction (Harvey Fineberg, President of the Institute of Medicine). Medical News Today April 7, 2005 Influenza Intrigue Nature Magazine, in its February 24 issue, reported that Henry Niman, a biologist with Recombinomics, last November was examining flu virus gene sequences that were placed in GenBank, a public database in New Mexico run by the World Health Organization. Niman found a strain of human flu virus that was created in 1940 in a London lab by scientists who were experimenting with the virus that had caused the flu pandemic of 1918. The problem is that this mutated human flu virus was placed in GenBank by researchers at Chungnam National University Daejon, South Korea. It had been obtained from a pig! This flu gene sequence doesn’t exist in nature. It had to be artificially implanted into pigs. Bill Sardi LewRockwell.com April 7, 2005 WHO: Combined virus could be deadlier BANGKOK: Two strains of bird flu in Asia may combine to create a highly lethal and easily transmissible virus, a UN health official warned yesterday, amid widespread fears that the disease could cause the next human pandemic. Thestar Online April 6, 2005 Government Steps Up Fight Against Flu CDC Expands Quarantine Capabilities April 6, 2005 -- Federal health officials say they are stepping up efforts to protect the nation against influenza, amid concerns that bird flu could enter the U.S. from Asia and cause a pandemic. Todd Zwillich Reviewed By Brunilda Nazario WebMD Medical News April 6, 2005 Marburg haemorrhagic fever in Angola - update 7 As of 5 April, the Angolan Ministry of Health has reported 181 cases of Marburg haemorrhagic fever. Of these, 156 have died. Cases have now been reported from five provinces. Uige remains the epicentre of the outbreak. While children under the age of 5 years initially accounted for around 75% of cases, recent cases are including an increasing number of adults. One person is currently under investigation for Marburg haemorrhagic fever in the Democratic Republic of Congo. OMS April 6, 2005 North Korean bird flu outbreak not the feared strain But Juan Lubroth, head of infectious diseases at the FAO, told New Scientist that the evidence is indirect. “The North Koreans made a vaccine using virus from the sick chickens, and vaccinated chickens in the region around the outbreak,” he says. “Those chickens show a high level of antibodies to H7.” Debora MacKenzie NewScientist.com April 7, 2005 Bird flu jitters cause bank fears in Asia Investment banks are starting to issue warnings on the risks avian influenza poses to the economies and financial markets of East Asia, as health experts struggle to assess whether the disease has the potential to cause a pandemic at all. The New York Times April 7, 2005 A best defense against bird flu? But should the rest of us do the same? Until there's a vaccine against the virus (and clinical tests of a prototype have only just begun), Tamiflu will probably be our best defense. Why not, just in case, pester our doctors into prescribing a five-day packet of pills? . Deborah Franklin The New York Times April 6, 2005 WHO Expert: Bird Flu Strains Could Combine Two strains of bird flu in Asia may combine to create a highly lethal and easily transmissible virus, a U.N. health official warned Wednesday, amid widespread fears that the disease could cause the next human pandemic. ALISA TANG PDT BANGKOK, Thailand April 5, 2005 Banks estimate costly risk of avian flu New Feature Keith Bradsher The New York Times April 5, 2005 Angola: Marburg Hemorrhagic Fever Outbreak Minor Emergency Bulletin no. 05ME021 Angola is currently experiencing an outbreak of Marburg hemorrhagic fever. The first cases were reported in Uige province in October 2004. As of 2 April, the Angola Ministry of Health (MINSA) has reported 163 cases with 150 fatalities. Cases have been identified in Uige, Luanda, Cabinda, Malange, and Kuanza Norte provinces. Uige remains the epicentre of the outbreak. To date, all cases detected in other provinces are thought to have originated in Uige. (Source: WHO, Marburg hemorrhagic fever in Angola, Update 6). See table, page 2. Source: International Federation of Red Cross And Red April 4, 2005 The sequence of the HA gene of an H5N1 isolated from the crested eagles The sequence of the HA gene of an H5N1 isolated from the crested eagles smuggled into Belgium is available at GenBank.  There are 645 bp available for A/crested eagle/Belgium/01/2004.  The sequence is closely related to the HA from the isolate, A/Thailand/Kamphaengphet-Nontaburi/04(H5N1), from the mother of the index case in Thailand as well as isolates from tigers (A/tiger/Thailand/CU-T3/2004(H5N1), A/tiger/Thailand/SPB-1/2004(H5N1),  that died at the Sri Lanka tiger zoo last season.  Sequences from isoaltes chickens and patients in Thailand are also closely related. Although the birds came from Tibet, the sequence data would point toward infection in Thailand Dr Niman Recombinomics Commentary Vol. 11, No. 5 May 2005 Highly Pathogenic H5N1 Influenza Virus in Smuggled Thai Eagles, Belgium Steven Van Borm,* Isabelle Thomas,† Germaine Hanquet,† Bénédicte Lambrecht,* Marc Boschmans,* Gérald Dupont,† Mireille Decaestecker,* René Snacken,† and Thierry van den Berg* *Veterinary and Agrochemical Research Centre, Brussels, Belgium; and †Scientific Institute of Public Health, Brussels, Belgium We report the isolation and characterization of a highly pathogenic avian influenza A/H5N1 virus from Crested Hawk-Eagles smuggled into Europe by air travel. A screening performed in human and avian contacts indicated no dissemination occurred. Illegal movements of birds are a major threat for the introduction of highly pathogenic avian influenza. CDC April 5, 2005 Children bear brunt of Marburg virus Health officials in Angola say children have borne the brunt of a deadly outbreak of the Ebola-like virus, Marburg. Africa correspondent Zoe Daniel ABC NEWS April 4, 2005 Marburg disease outbreak in Angola now worst-ever recorded: UN health agency As the Marburg virus outbreak in Angola became the worst-ever recorded with 163 cases so far, 150 of them fatal, the United Nations health agency said today significant international aid will be needed to control the rare but highly lethal haemorrhagic disease with epidemic potential. UN NEWS CENTRE April 4, 2005 HHS funds development of cell-based flu vaccines – Sanofi Pasteur has won a $97 million federal contract to develop cell-culture technology for making influenza vaccines and to design a facility to use this technology to make a pandemic flu vaccine, federal officials have announced. CIDRAP News April 4, 2005 Set aside funds now for bird flu, WHO expert says WASHINGTON, April 4 (Reuters) - The world's governments should set aside 5 percent of their spending on influenza vaccines to help get ready for the next big flu epidemic, a World Health Organization expert proposed on Monday. Maggie Fox Health and Science Correspondent Reuters Avril 2, 2005 Order OKs Bird Flu Quarantine in U.S. WASHINGTON (AP) - President Bush signed an executive order Friday authorizing the government to impose a quarantine to deal with any outbreak of a particularly lethal variation of influenza now found in Southeast Asia. Avril 1, 2005 Executive Order: Amendment to E.O. 13295 Relating to Certain Influenza Viruses and Quarantinable Communicable Diseases By the authority vested in me as President by the Constitution and the laws of the United States of America, including section 361(b) of the Public Health Service Act (42 U.S.C. 264(b)), it is hereby ordered as follows: Section 1. Based upon the recommendation of the Secretary of Health and Human Services, in consultation with the Surgeon General, and for the purpose set forth in section 1 of Executive Order 13295 of April 4, 2003, section 1 of such order is amended by adding at the end thereof the following new subsection: "(c) Influenza caused by novel or reemergent influenza viruses that are causing, or have the potential to cause, a pandemic.". Sec. 2. This order is not intended to, and does not, create any right or benefit, substantive or procedural, enforceable at law or in equity by any party against the United States, its departments, agencies, entities, officers, employees or agents, or any other person. George W. Bush President USA Avril 1, 2005 Le virus de Marburg s'étend à une quatrième province d'Angola Une quatrième province d'Angola est touchée par l'épidémie de fièvre hémorragique de Marburg, dont le bilan s'alourdit d'heure en heure dans le pays, avec déjà au moins 130 morts sur 137 cas recensés, selon le dernier bilan officiel publié vendredi par le ministère de la Santé. TELEVISION Suisse Romande Avril 1, 2005 Fièvre de Marburg : 9 personnes isolées en Italie, 2 cas suspects en RDCongo Neuf personnes ayant été en contact avec un malade atteint de la fièvre hémorragique de Marburg ont été placées en isolement dans un hôpital italien, a annoncé vendredi 1er avril 2005 l'Organisation mondiale de la santé (OMS), qui a fait état de deux cas suspects en République démocratique du Congo (RDC). MediaTropical April 1, 2005 Sanofi pasteur Awarded $97 Million HHS Contract to Accelerate Cell-Culture Pandemic Influenza Vaccine Development Major U.S. public health initiative complements sanofi pasteur's leadership in global pandemic preparedness LYON, France and SWIFTWATER, Pa., April 1 /PRNewswire-FirstCall/ -- Sanofi pasteur, the vaccines business of the sanofi-aventis Group, has been awarded a $97 million contract from the U.S. Health and Human Services Department (HHS) to speed the production process for new cell culture influenza vaccines in the U.S. and the design of a U.S.-based cell-culture vaccine manufacturing facility. Sanofi pasteur, the global leader in influenza vaccines, has assembled dedicated teams at its Swiftwater, PA, and Marcy L'Etoile, France, sites to support this critical project. Pr Newswire April 1, 2005 WHO Says Angola's Marburg Outbreak Controllable VOA News April 1, 2005 HK Stadium may be used as clinic if bird flu hits Chester Yung The Standard China's Business Newspaper April 1, 2005 Interim Guidance about Avian Influenza A (H5N1) for U.S. Citizens Living Abroad - Update Center for Diesease Control (CDC), National Center for Infectious Diseases April 1, 2005 Government aren't telling people the truth about bird flu preparation NewsTarget,com April 1, 2005 North Korea culls hundreds of thousands of chickens to stop spread of bird flu NewsTargt.com April 1, 2005 Britain working to develop action plans in advance of flu pandemic News Target.com April 1, 2005 Flu Pandemic Coming, U.S. Not Prepared Immediate action is needed to prepare the United States for a deadly pandemic of influenza, the Infectious Diseases Society of America (IDSA) is telling policymakers. ScienceDaily Diana Olson, [email protected] Office: (703) 299-0201 Cell: (202) 320-8626 April 1, 2005 New Cases Of Bird Flu Underscore Dangers Of A Global Pandemic Dragan Stankovic World Socialist Web April 1, 2005 Marburg fears in Italy Geneva - Italian hospital staff have put nine patients in isolation after they had been suspected of having contact with the Marburg virus, an Ebola-like killer which has broken out in Angola, the United Nations health organisation said on Friday. News 24 .com