Name:                                                                                   GENETICS                                              Name:

 

Multiple Choice

1.  DNA

                a) is a complex molecule      b)  is not a molecule

                c) is a simple molecule                         d)  is not a gene

 

2.  DNA is an abbreviation for

                a) ribonucleic acid                                b) deoxyribonucleic acid

                b) denatured alcohol                           d) none of these

 

3.  DNA makes up the

                a) chromosome                     b) nucleus             c) gene                   d) nucleolus

 

4.  The DNA molecule consists of a series of ___ joined together

                a) compounds       b) bases c) sugars                d) nucleotides

 

5.  The base adenine is always joined with

                a) thymine             b) cytosine            c) guanine             d) phosphate

 

6.  DNA controls

                a) making of proteins                           c) manufacturing ATP

                b) making of vitamins                          d) no activities of the cell

 

7.  RNA uses a series of _______  in its work

                a) triplet bases                      b) quad bases       c) twin bases         d) six bases

 

8.  Human eggs and sperms have 23 chromosomes each, while all other body cells have

                a) 12 chromosomes              b) 46 chromosomes              c) 72 chromosomes              d) 23 chromosomes

 

9.  Which combination of genes is heterozygous?

                a) AA     b) aa       c) Aa      d) none of the above

 

10. Drosophilia is a

                a) fruit fly               b) house fly           c) damselfly           d) horse fly

 

11.  Humans are similar to oak trees in that the hereditary materials used by both organism are

                a) nucleic acids                     b) cells   c) oxygen and carbon dioxide            d) enzymes

 

12.  DNA is found in what part of the cell?

                a) nucleus              b) enzymes            c) membrane          d) ribosomes

 

 

13.  Mutations occur when

                a) the wrong nucleotide is attached on a DNA strand

                b) the nucleus fails to produce proteins

                c) the DNA passes through the cell membrane

                d) white blood cells attack invading microbes.

 

14.  Mendel crossed pea plants with green seeds (yy) with yellow seeds (YY).  The offspring were

                a) 100% green       b) 50% yellow       c) 100% yellow     d) 25% green

 

15.  If the F1 plants from problem 1 were crossed with each other, what percentage of the offspring would be green?

                a)50%     b) 0%      c) 100%  d) 25 %

 

16.  Organisms with the genotypes Bb and BB have the same phenotype because

                a) B is dominant over b                       b) genes separate independently

                c) genes assort independently                          d) all of these

 

17.  In pea plants, purple flowers are dominant over white flowers.  If two heterozygous purple flowered plants are crossed, the resulting ratio of phenotypes in the F1 generation is

                a) 1:1       b) 3:1      c) 1:2:1    d) none of these

 

18.  Four- o'clocks exhibit incomplete dominance for flower colour.  If two heterozygous pink (rw) plants are crossed, the probable ratio of genotypes in the offspring is

                a) 3 rw:1 ww          b) 1 rr: 2 rw: 1 ww c) 1 rr: 1 rw: 1 ww  d) 1 rr: 1 ww

 

19.  Meiosis is called reduction division because it results in

                a) haploid cells                     b) diploid cells

                c) fewer cells than before    d) none of the above

 

20.  If a heterozygous, short haired black rabbit (BbSs) is crossed with a long- haired brown rabbit (bbss), the percent of short haired brown rabbits in the F1 generation is

                a) 100%  b) 50%    c) 25 %   d) 0%

The next two questions are concerned with hemophilia.

21.  An 8 year old boy exhibits hemopheilia.  He most probably inherited this sex-linked disease from:

                a) his mother         b) his father                           c)  a gene mutation

                d) both of his parents

 

22.  If by some chance this boy did live past puberty and marreid a woman who carried the diseasse, what is the probability that their daughters would have the disease?

                A)100%                  b) 50%                    c) 25%                    d)0%

 

23.   A new inheritable trait that appears without any visible change in the chromosomes is most likely due to a:

                a) dominant gene                 b) recessive gene c) gene mutation                  d)sex-linked trait

 

The next three questions are based on the following about parental blood types and a child

                Parents 1: type A and type A

                Parents 2: type O and type O

                Parents 3: type AB and type O

                Parents 4: type B and type A

                child    : type O

24.  The only parents that could not be parents of child X are

                a) 1          b) 2         c) 3          d) 4

 

25.  If the child were blood type AB, which of the above could be its parents

                a) 1          b) 2         c) 3          d) 4

 

26.  If the child were bood type B, which of the abouve could be its parents?

                a) 1 and 2               b) 2 and 3               c) 1 and 3               d) 3 and 4

 

Use the following key to answer the next five questions

Key

A--- autosomes

B--- X chromosome

C--- Y chromosome

D--- X and Y chromosomes

 

27.  ______ These are referred to as sex chromosomes

28.  ______ Are in excess in Klinefelter's disease

 

29.  ______ We normally have 22 pair of them

 

30.  ______ Missing in Turner,s Syndrome

 

31.  ______ An extra one is the cause of down's syndrome

 

32.  The weakest chemical bonds are between

                a) nitrogen bases b) bases and sugars            c) sugars and phosphates 

                d) bases and phosphates

 

Fill in the blanks

33.  The study of heredity began with the work of ____________.

 

34.  Female sex chromosomes are represented by the letters ___________, while those of the male sex are _______. (human)

 

35.  When a pure tall pea plant is crossed with a pure dwarf plant, all the resulting pea plants are ______ in size.  This experiment shows that the characteristic for tallness was ____________ and the characteristic for dwarfness was_____________.

 

36.  In replicating, the sequence of _______________ in the DNA molecule must be duplicated exactly.

 

37.  On the rare occasions of proofreading error, a small random change in the genetic instructions is called a _______________.

 

 

38.  On the line beside each phrase in column I print the letter of the matching word from Column II

                column I                                                                                                                                 column II

_____ The stage in mitosis in which chromosomes migrate to opposite poles                        a) albino

_____ Threads along which chromosomes migrate during mitosis                                            b) anaphase

_____ The gene conbination expressing pure dwarf                                                                    c) interphase

_____ Great American geneticist                                                                                                      d) mutation

_____ An organism lacking pigmentation                                                                                      f) prophase

_____ A 1:2:1 combination of offspring indicates that boyh parents were                               g) Muller

_____ a gene which produces a fatal characteristic                                                                      h) tt

_____ the biologist who was first to show that gene mutations can be caused by                 i) mongolism

      radiation                                                                                                                                          j) pure tall

_____ Down's syndrome is the medical name for                                                                          k) sex linked

_____ a cross between a horse mare and a male donkey                                                             l) Watson

                                                                                                                                                                m) Mendel

                                                                                                                                                                n) hybrid

                                                                                                                                                                o) zebra

                                                                                                                                                                p) cross-linked

                                                                                                                                                                q) TT

                                                                                                                                                                r) mule

                                                                                                                                                                s) spindles

 

 

Short answer

 

1.  Briefly describe the stage that a cell goes through before it begins the actual process of mitosis

 

 

 

 

 

2.  What are three differences between mitosis and meiosis?

 

 

 

 

 

 

3.  How does mitosis differ in plant and animal cells?

 

 

4.  Distinguish between the following terms

                diploid and haploid

 

 

 

                homozygous and heterozygous

 

 

 

                transcription and translation

 

 

 

                centriole and kinetochore

 

 

 

                chromosome and chromatid

 

 

 

 

5.  Briefly explain one of the following Laws of heredity

    (Law of segregation, Law of independent assortment)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

6.  The following group of letters represents a strand of DNA.  Give the corresponding mRNA, tRNA and amino acid sequence which  is transcribed.

 

DNA   A C G T C G A C T C G A T G C

 

MRNA

 

TRNA

 

amino

acids

 

 

 

 

 

 

 

 

 

 

 

 

 

 

7.  Why can't a DNA molecule leave the nucleus?

 

 

8.  How do amino acids get to a ribosome?

 

 

9  Explain one mutation and give one example.

 

 

 

 

10.  DNA replication does not take place between Meiosis I and Meiosis II.  What would likely happen to the gametes if it did take place?

 

 

 

 

 

 

 

11.  What advantages, if any, does a sexually reproducing organism have over an asexually reproducing one?

 

 

 

 

 

12.  In  mice, the gene for coloured fur is dominant over the gene for white fur.  A hybrid male is crossed with a pure white female.

a) use symbols to represent the genotype of the parents

 

 

b) use a Punnett square to calculate the phenotypes and genotypes of the F1 generation.

 

 

 

 

 

 

 

 

 

 

 

 

13.  Is it possible for two brown eyed parents to have a blue-eyed offspring?  Use a Punnett square to prove your answer?

 

 

 

 

14.  In sheep, white hair (W) is dominant over black hair (w).  A test cross was make between a black sheep and a white sheep.  One half of the offspring were black and one half were white.  What is the genotype of the white

parent?  How do you know?

 

 

 

 

 

 

 

 

 

 

 

15.  In the diagram, label each of the stages of mitosis.  Also identify the nucleus, nucleolus, spindle, chromatids and cell plate.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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