FC UNITED'S march to the Moore and Co Solicitors League second division title was temporarily halted at Gigg Lane as Flixton ended their 18-match unbeaten run.
And the red rebels could have few complaints about their 2-1 defeat in front of a crowd of 1,924.
Graham Vaughan gave Flixton a deserved 36th minute lead when he curled in a shot from the edge of the box and there was further heartache for FC United as Lee Wilkinson made it 2-0 early in the second-half.
Skipper Dave Chadwick pulled one back for the hosts four minutes from time, but the visitors held on in a frantic finish.
2 Rob Nugent
3 Gareth Ormes
4 Chris Simms
5 David Chadwick(captain)
6 Billy McCartney
7 Josh Howard
8 William Aherne
9 Steve Torpey
10 Adie Orr
11 Rory Patterson
Subs:
12 Dave Swarbrick
14 Simon Carden
15 Steve Spencer
Attendance 1924
Scorers
Chadwick 86