SoyZymeTM is a proprietary phyto (plant derived) extract containing approximately 6% of the total weight as pure isoflavones, the majority of which is the isoflavone Genistein. Genistein is one of the most active isoflavones of soy. Soy and its derivative isoflavones are clinically shown to be agents that provide protection against various conditions including heart disease and help normalize female related health issues such as PMS, menopause, and osteoporosis. Genistein's role as a "weak estrogen" is being extensively studied for its possible ability to combat some forms of cancer, including breast and prostate.

SoyZyme was developed to help immunomodulate the body, remove immune complexes and truncated protein debris from circulation, control cellular proliferation, prevent bone mass loss, and enhance blood rheology. SoyZyme combines two powerful phytonutrients: Genistein and a blend of Proteases. The combination of these provide far ranging protective and therapeutic benefits to the body.

Component Benefits:

Genistein:
Genistin and Genistein are isoflavones mostly found in soybeans.� Genistin is the glycosidic form of the isoflavone and Genistein is the aglycone form. The aglycone form is the form most absorbed into the intestinal mucosa. When ingested in the form of genistin (the glycosidic form) the intestinal bacteria remove the glycosidic moiety and convert it to Genistein which is then absorbed. In the present formulation of highly concentrated pure Genistein, additional glycosidases were added to ensure the conversion of the genistin present into the absorbable aglycone form.

• provides estrogenic effect in some tissues (bones, heart, brain, lungs, prostate, genitourinay),
• provides anti-estrogenic effect on the breast
• the duality of Genistein effect on various tissues is due to a specific receptor
• abundant on other tissues but not on breast tissues;
• interference with stimulated tissue proliferation in breast and uterus;
• antioxidants properties;
• inhibition of tyrosine kinase and prevent signals for cell proliferation;
• inhibition of angiogenesis;
• helps lower cholesterol

Protease:
The formulation contains a mixture of highly active proteases with wide range of pH stability, activity, and ability to cleave several types of peptide bonds. In fact, the proteases have endopeptidase as well as exopeptidase (amino and carboxypeptidase) activities. When taken on an empty stomach, oral proteases pass readily into the blood� stream where they bind to alpha 2-macroglobulin. The binding to alpha 2-macroglobulin "hides" the exogenous protease from the immune system, yet allowing it to maintain its hydrolytic activity and act upon substrates small enough to come in contact with the protease/alpha 2-macroglobulin complex. In fact, contrary to some belief, alpha 2-macroglobulin is not a protease inhibitor per se. Some proteases when bound to alpha 2-macroglobulin maintain their catalytic activities, while other proteases do not. This duality in effect is due to the size of the protease and/or its substrates: large substrates may not be able to reach the active site of the trapped protease whereas smaller substrates may easily reach within the complex and be acted upon by the protease.

The proven benefits of oral proteases include:

• enhanced digestion of proteins in the GI tract;
• removal of circulating immune complexes before they cause auto immune disorder
• modulation of cytokines;
• enhanced blood rheology;
• fibrinolytic and thrombolytic activity without the bleeding side-effects of other thrombolytics;
• enhanced healing of wounds;
• scavenging of circulating oxidized proteins, thus minimizing free radicals cascading effect;

Amylase and Glucoamylase:
Ensures the conversion of the genistin present to the more absorbable genistein.

Calcium Citrate:
Buffers the Protease, making it more bio available.

� Non-Member Price: $29.95
Member Price: $19.95
+ $3.00 S&H for 1st bottle of supplement and $1.00
for each additional bottle in the same order.

Each 362 mg capsule of SoyZyme provides:

Soy Isoflavones 40%, 57 mg. (20 mg. Genistein)
Protease, 150,000 HUT
Amylase, 1,000 DU
Glucoamylase, 0.7 DU
Calcium Citrate, 40 mg. (9 mg. Calcium)

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