'Esto ene un modulo
Declare Function ShellExecute Lib "shell32.dll" Alias "ShellExecuteA" (ByVal hwnd As Long, ByVal lpOperation As String, ByVal lpFile As String, ByVal lpParameters As String, ByVal lpDirectory As String, ByVal nShowCmd As Long) As Long
Public Const SW_SHOW = 1

'Esto en cualquier boton de comando de un formulario
Dim FrmVentaActiva As Form
Set FrmVentaActiva = Me
ShellExecute FrmVentaActiva.hwnd, "open", "C:\Ruta\DATOS.MDB", "", "", SW_SHOW
DoCmd.Quit

Un poco rebuscada pero funciona.